Akti-1/2

Catalog No.S7776 Synonyms: Akt Inhibitor VIII

Akti-1/2 Chemical Structure

Molecular Weight(MW): 551.64

Akti-1/2 is a highly selective Akt1/Akt2 inhibitor with IC50 of 58 nM/210 nM, respectively, about 36-fold selectivity for Akt1 over Akt3.

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Cited by 3 Publications

2 Customer Reviews

  • AKTi-1/2 inhibits human HCC cells in vitro. Human HCC HepG2 cells (A–F), Huh-7 cells (G), primary human HCC cells (“Pri HCC”, G) or the primary liver cells (“Pri liver cells”, G) were treated with/out applied concentrations of AKTi-1/2 for indicated time; Cell survival (A, B and G), proliferation (C and D) and apoptosis (E and F) were tested by the listed assays. Data were shown as the mean (n = 5) with the standard deviation (SD). Experiments in this figure were repeated three times, with similar results were obtained. *P < 0.05 vs. “C” (untreated control) group.

    Biochem Biophys Res Commun, 2016, 480(3):334-340. Akti-1/2 purchased from Selleck.

    Autophagy inhibitors sensitize AKTi-1/2-induced cytotoxicity against HCC cells. HepG2 cells were treated with/out AKTi-1/2 (5/10 μM) for indicated time; Listed proteins were tested by Western blot assay (A); The percentage of LC3B-II GFP puncta positive cells ("autophagic cells") was calculated (B). HepG2 cells, pretreated with 3-methyladenine (“3 MA”, 10 mM), ammonium chloride (“NH4Cl”, 1 mM) or bafilomycin A1 (“BafA1”, 1 μM) for 1 h, were treated with AKTi-1/2 (10 μM) for applied time; Cell survival (CCK-8 assay, C) were tested. The IC50 was also determined (D).

    Biochem Biophys Res Commun, 2016, 480(3):334-340.. Akti-1/2 purchased from Selleck.

Purity & Quality Control

Choose Selective Akt Inhibitors

Biological Activity

Description Akti-1/2 is a highly selective Akt1/Akt2 inhibitor with IC50 of 58 nM/210 nM, respectively, about 36-fold selectivity for Akt1 over Akt3.
Targets
Akt1 [1]
(Cell-free assay)
Akt2 [1]
(Cell-free assay)
Akt3 [1]
(Cell-free assay)
58 nM 210 nM 2119 nM
In vitro

In a cell-based IPKA (C33A) assay, Akti-1/2 inhibits Akt1 and Akt2 with IC50 of 305 nM and 2086 nM, respectively. In HT29, MCF7, and A2780 cells, Akti-1/2 induces cell apoptosis by dramatically increasing caspase-3 activity. [1] In liver cells, Akti-1/2 blocks insulin regulation of PEPCK, G6Pase expression, and FOXO1 activity. [2] Akti-1/2 also strongly potentiates PAR-1-mediated platelet aggregation by blocking PKB. [3] In HCC827, NCI-H522, NCI-1651, and PC-9 cells, Akti-1/2 inhibits cell growth with IC50 of 4.7 μM, 7.25 μM, and 9.5 μM, when in combination with gefitinib, Akti-1/2 causes enhanced inhibition of cell growth and apoptosis. [4]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
MDA-MB-468 cells M1zHZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MWmxNEDPxE1? M3yz[WN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj20Olgh[2WubIOgbY4heHKnc3XuZ4Uhd2ZiMUCgeW0h[2iub4LvdZVqdmViYomgV3JDKGG|c3H5MEBIUTVyPUKuOlYh|ryP MlLvNVg3QTF6OUS=
MDA-MB-231 cells M3zwOmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1;mVFExKM7:TR?= M3\KVWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN|Eh[2WubIOgbY4heHKnc3XuZ4Uhd2ZiMUCgeW0h[2iub4LvdZVqdmViYomgV3JDKGG|c3H5MEBIUTVyPUSuOVUh|ryP M3LSNFE5PjlzOEm0
MCF7 cells NWewTlNJS3m2b4TvfIlkcXS7IHHzd4F6 MYOxNEDPxE1? M1TEZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMhcW5icILld4Vv[2Vib3[gNVAhfU1iY3jsc5JweXWrbnWgZpkhW1KEIHHzd4F6NCCJSUWwQVAvPDFizszN NGDvT|AyQDZ7MUi5OC=>
184B5 cells M{XaU2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmK4NlAh|ryP NUPrb|lQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hOTh2QkWgZ4VtdHNiYYSgNlAhfU1iY3jsc5JweXWrbnWgZpkhW1KEIHHzd4F6NCCJSUWwQVI2Njd4IN88US=> MWexPFY6OTh7NB?=
NCI-H1563 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEPwZnBKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVU3OyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNUSyOFYh|ryP NHT4bIpUSU6JRWK=
NCI-H1618 cel M3ezS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnSyTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2NVgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOS57OUiyJO69VQ>? NX61bZA6W0GQR1XS
NCI-H1623 cell NU[5XFRQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XUfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlI{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTVwMEW5OkDPxE1? MUfTRW5ITVJ?
NCI-H1648 cell NH\VRpdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXLJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPzV3MTFOwG0> NEHGdYtUSU6JRWK=
NCI-H1650 cell Mk\5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2XJVmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTFwNUGzOEDPxE1? NHXNc4pUSU6JRWK=
NCI-H1651 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIPX[WpKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY2OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF4LkSzN|gh|ryP NWHBNnRYW0GQR1XS
NCI-H1703 cell NWXobXY5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIPY[nRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVcxOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF3LkW3O{DPxE1? M2jweXNCVkeHUh?=
NCI-H1734 cell M1fuV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkTNTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG3N|Qh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC55N{i4JO69VQ>? M37nenNCVkeHUh?=
NCI-H1755 cell NHG3W3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4[2eWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixO|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5yNUWzNUDPxE1? M1XPTXNCVkeHUh?=
NCI-H1770 cell NHi3NldIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUjkfnU6UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE4PzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|ND6xO|k{KM7:TR?= Mkj6V2FPT0WU
NCI-H1792 cell MnPoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1i4R2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixO|kzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjlwOEO3PUDPxE1? MVHTRW5ITVJ?
NCI-H1963 cell MlvnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUm2N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE6Njd2OUSg{txO M1fZfXNCVkeHUh?=
NCI-H1993 cell MnzxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnH6TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG5PVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi54MUWg{txO NUPxdGo2W0GQR1XS
NCI-H2009 cell NV7rWnNPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGTUfIhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlAxQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwM{mwNVkh|ryP MorVV2FPT0WU
NCI-H2030 cell NHqwUVRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1nGU2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFMxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS57NES4N{DPxE1? M3r4WHNCVkeHUh?=
NCI-H2122 cell NYjLc2xtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn\2TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC5zM{i1JO69VQ>? NUjXZ5NuW0GQR1XS
NCI-H2126 cell M{jKO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjN|N{Gg{txO MVHTRW5ITVJ?
NCI-H2170 cell NF7SdYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX\6e29VUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zOD6xNFI5KM7:TR?= NELEdlZUSU6JRWK=
NCI-H2196 cell NHP1WnhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGHkcGZKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE6PiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2LkiwNFMh|ryP M2KxOnNCVkeHUh?=
NCI-H2228 cell MoHyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Moi1TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKyNlgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ6NkC0JO69VQ>? NWj1NYJNW0GQR1XS
NCI-H2342 cell MoT1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVTJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkO0NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQTN5N{mg{txO M1jF[HNCVkeHUh?=
NCI-H2347 cell NVTOfVNKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVXYeZMyUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFI{PDdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zNj6xOVgyKM7:TR?= NELk[3VUSU6JRWK=
NCI-H2405 cell MkCxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkSwOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjR{MUKg{txO MV7TRW5ITVJ?
NCI-H2452 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mk\GTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEK0OVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPi54NUm0JO69VQ>? MlLKV2FPT0WU
NCI-H292 cell M1LlU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\RXWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyPVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjB2OEO3JO69VQ>? MYXTRW5ITVJ?
NCI-H345 cell NUHpS21NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYTVZYFRUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFM1PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF4LkK3NFYh|ryP M2PSdXNCVkeHUh?=
NCI-H358 cell NGPFO2xIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIXmRXdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IN|U5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTlwN{KzN{DPxE1? MXHTRW5ITVJ?
NCI-H460 cell M1i3XGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNE[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE43Ojl7MzFOwG0> MkLuV2FPT0WU
NCI-H520 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFGzSlNKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOVIxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5zM{OwN{DPxE1? NF3NdXFUSU6JRWK=
NCI-H522 cell M3myS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkPiTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjB6N{Sg{txO MWHTRW5ITVJ?
NCI-H526 cell NYnYfXlJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4PmU2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56OEez{txO M3Hme3NCVkeHUh?=
NCI-H596 NFXLS2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{LEe2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1PVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy53N{C4JO69VQ>? NVXMeGF2W0GQR1XS
NCI-H630 cell MlfCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3XsNmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi2N|Ah[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02NjVzMEW1JO69VQ>? MoSyV2FPT0WU
NCI-H64 cell MkLSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH;TZ|lKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOlQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi53NEOxJO69VQ>? Mm\EV2FPT0WU
NCI-H650 cell M3fqbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFvlPWRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOlUxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py53OUi3O{DPxE1? NVLQfYhLW0GQR1XS
NCI-H661 cell NGjMUJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFTZXllKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOlYyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS52MkOyOkDPxE1? NEXTXI5USU6JRWK=
NCI-H747 cell M1iyU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{S3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43Ojd7OTFOwG0> M1\zTnNCVkeHUh?=
NCI-H838 cell NXPQRoZtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1jY[mlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi4N|gh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OS52MUG4JO69VQ>? MlOwV2FPT0WU
NCI-N87 cell M33wcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3TRO2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLV64O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI6NjNyNEKg{txO NGnIdZpUSU6JRWK=
NH-12 cell NWjOeHJmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEjRTmRKdmirYnn0bY9vKG:oIHj1cYFvKE6KLUGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43ODh4NDFOwG0> NULVNoZwW0GQR1XS
NKM-1 cell NGLWS4hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYfWZ|l6UW6qaXLpeIlwdiCxZjDoeY1idiCQS12tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPzV7MkOg{txO M{\neXNCVkeHUh?=
NMC-G1 cell NVX6NZp5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1nMZmlvcGmkaYTpc44hd2ZiaIXtZY4hVk2FLVexJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFIvPjZ7MzFOwG0> NVrFS28{W0GQR1XS
NOS-1 cell MmTVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6zOlk2OyEQvF2= MVvTRW5ITVJ?
NUGC-3 cell NUX4cFl3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NY\HUldQUW6qaXLpeIlwdiCxZjDoeY1idiCQVVfDMVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPi53OUC2JO69VQ>? NHrnUVVUSU6JRWK=
NY cell NU\ke2U2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWfsWVRkUW6qaXLpeIlwdiCxZjDoeY1idiCQWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOxMlE5PjRizszN MVzTRW5ITVJ?
OAW-42 cell NFG1fmVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF[3RZdKdmirYnn0bY9vKG:oIHj1cYFvKE:DVz20NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOzF3NkWg{txO NEPvNYFUSU6JRWK=
OCI-AML2 cell NFzzU4hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{[xTWlvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oy5{NUOxJO69VQ>? MUTTRW5ITVJ?
OCUB-M cell NEHs[5FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVrFcGQ{UW6qaXLpeIlwdiCxZjDoeY1idiCRQ2XCMW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04Njd{MUWyJO69VQ>? MYDTRW5ITVJ?
OE19 cell NIDSWYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{TvVmlvcGmkaYTpc44hd2ZiaIXtZY4hV0VzOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuO|Y3QDRizszN NEPDOVJUSU6JRWK=
OE33 cell MkftS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGfpO5BKdmirYnn0bY9vKG:oIHj1cYFvKE:HM{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlg5QTJ4IN88US=> MWDTRW5ITVJ?
OMC-1 cell NVizPIZpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWXJcohq[mm2aX;uJI9nKGi3bXHuJG9OSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT6yOVA6QCEQvF2= M1\wTHNCVkeHUh?=
OS-RC-2 cell M33POGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoezTY5pcWKrdHnvckBw\iCqdX3hckBQWy2UQz2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OjNyNzFOwG0> MlPvV2FPT0WU
OVCAR-3 cell NEn4[mJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlg1PDF3IN88US=> NITCcIdUSU6JRWK=
OVCAR-4 cell NY\KWnFxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NG\zfGlKdmirYnn0bY9vKG:oIHj1cYFvKE:YQ1HSMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC52Nk[g{txO M{L0eXNCVkeHUh?=
P12-ICHIKAWA cell M2jOV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGD3[INKdmirYnn0bY9vKG:oIHj1cYFvKFBzMj3JR2hKU0GZQTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0Mlc3QDNizszN MYjTRW5ITVJ?
P30-OHK cell MnLmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVn3dml[UW6qaXLpeIlwdiCxZjDoeY1idiCSM{CtU2hMKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC53M{[g{txO MXnTRW5ITVJ?
PA-1 cell NV7rWmRLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHPNT|VKdmirYnn0bY9vKG:oIHj1cYFvKFCDLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlA4PjF3IN88US=> NIL5PGZUSU6JRWK=
PANC-03-27 cell M1L6R2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYntcZh5UW6qaXLpeIlwdiCxZjDoeY1idiCSQV7DMVA{NTJ5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD63NVA5OiEQvF2= MYrTRW5ITVJ?
PANC-10-05 cell NH;DO4hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWrJcohq[mm2aX;uJI9nKGi3bXHuJHBCVkNvMUCtNFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC57OUW5JO69VQ>? NXvqSGdmW0GQR1XS
PC-3 cell MlrwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWPUUFVYUW6qaXLpeIlwdiCxZjDoeY1idiCSQz2zJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVAvPTF|NTFOwG0> NXTwXJE5W0GQR1XS
PF-382 cell NGP2OWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEjpNldKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjZ6Mkig{txO M33ndHNCVkeHUh?=
RCC10RGB cell NGO2SlRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfFRVl{UW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwNkW2O{DPxE1? MkXzV2FPT0WU
RD cell M4[xc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnLRTY5pcWKrdHnvckBw\iCqdX3hckBTTCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJyLk[wN|Yh|ryP MoLnV2FPT0WU
REH cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1y0bWlvcGmkaYTpc44hd2ZiaIXtZY4hWkWKIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOFg5OyEQvF2= NXvuXpViW0GQR1XS
RERF-LC-MS cell MkjQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlK1TY5pcWKrdHnvckBw\iCqdX3hckBTTVKILVzDMW1UKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjZwMUO0O{DPxE1? NWr0dZhCW0GQR1XS
RKO cell Mo\zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJHJMVyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF7LkS0N|kh|ryP MWjTRW5ITVJ?
RO82-W-1 cell NWfzemFxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEfpTXRKdmirYnn0bY9vKG:oIHj1cYFvKFKROEKtW{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwMke4N{DPxE1? MlfpV2FPT0WU
RPMI-2650 cell MYrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVLUeox3UW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVI3PTBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke3PVQ4KM7:TR?= M{DafHNCVkeHUh?=
RPMI-8402 cell M3fvfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{HaeWlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST24OFAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTZwM{SzJO69VQ>? M{n6U3NCVkeHUh?=
RS4-11 cell M2W1SWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUDZcZJNUW6qaXLpeIlwdiCxZjDoeY1idiCUU{StNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjZ6NkS1JO69VQ>? NHrzSXBUSU6JRWK=
RT-112 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm\QTY5pcWKrdHnvckBw\iCqdX3hckBTXC1zMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22MlcyQTV{IN88US=> MnLzV2FPT0WU
RVH-421 cell NUPYdGllT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWPNfWU1UW6qaXLpeIlwdiCxZjDoeY1idiCUVlitOFIyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwM{[wOkDPxE1? NIrHSXRUSU6JRWK=
RXF393 cell NV\ldoFiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3XjdmlvcGmkaYTpc44hd2ZiaIXtZY4hWliIM{mzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPTh4MzFOwG0> M4n1eHNCVkeHUh?=
SBC-5 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX7Jcohq[mm2aX;uJI9nKGi3bXHuJHNDSy13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkCuPFMzPSEQvF2= NFftNJFUSU6JRWK=
SCC-25 cell MmG3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{\KfGlvcGmkaYTpc44hd2ZiaIXtZY4hW0OFLUK1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVUvQDF5OTFOwG0> MmSzV2FPT0WU
SCC-4 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1TINmlvcGmkaYTpc44hd2ZiaIXtZY4hW0OFLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlU6Ojh|IN88US=> MorTV2FPT0WU
SCC-9 cell MoLLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlvsTY5pcWKrdHnvckBw\iCqdX3hckBUS0NvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuNFg2OzZizszN MY\TRW5ITVJ?
SF126 cell M2XheWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWfwO|J[UW6qaXLpeIlwdiCxZjDoeY1idiCVRkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjZ5NE[g{txO NU\KXoJ1W0GQR1XS
SF268 cell MnTtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVLVZlN3UW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2NjF|OEeg{txO MVXTRW5ITVJ?
SF295 cell NYq2R4dDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjl3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOlE5OyEQvF2= NXvwZ3lbW0GQR1XS
SIG-M5 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnfvTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk43PjB2IN88US=> Mn7uV2FPT0WU
SJSA-1 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M33YUmlvcGmkaYTpc44hd2ZiaIXtZY4hW0qVQT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvQTB5MjFOwG0> NVfpRmJUW0GQR1XS
SK-CO-1 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNUORLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE43Ozl2IN88US=> MmKzV2FPT0WU
SK-LMS-1 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1;WcmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05Njd4NEWyJO69VQ>? M1vKb3NCVkeHUh?=
SK-LU-1 cell NXrjVmhyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYLveppiUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3MWU0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwMESzJO69VQ>? NX\wWWJOW0GQR1XS
SK-MEL-24 cell NE\wUlNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXnJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2HTD2yOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjF4N{Wg{txO MX7TRW5ITVJ?
SK-MEL-3 cell NWHIS3E3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MljMTY5pcWKrdHnvckBw\iCqdX3hckBUUy2PRVytN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIyNjR4OU[g{txO NFjMeIdUSU6JRWK=
SK-MES-1 cell MlP5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NICwVZNKdmirYnn0bY9vKG:oIHj1cYFvKFONLV3FV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5zMEC5OkDPxE1? NVzLbZBtW0GQR1XS
human SN12C cell M13LOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFW0fmxKdmirYnn0bY9vKG:oIHj1cYFvKFOQMULDJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOTl4NzFOwG0> NHzqOZlUSU6JRWK=
SNB75 cell NVPOcFk3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJHNPSjd3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz64Nlk4KM7:TR?= M37hW3NCVkeHUh?=
SNU-387 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH\mfmZKdmirYnn0bY9vKG:oIHj1cYFvKFOQVT2zPFch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjF7NUS0JO69VQ>? M1H3dnNCVkeHUh?=
SNU-423 cell M3XVXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV3Jcohq[mm2aX;uJI9nKGi3bXHuJHNPXS12MkOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlk1QTN|IN88US=> M2DaPHNCVkeHUh?=
SNU-C1 cell NI[0eVVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYC3c5E6UW6qaXLpeIlwdiCxZjDoeY1idiCVTmWtR|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjByOUS4JO69VQ>? M4rBXHNCVkeHUh?=
SNU-C2B cell M3PGVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIflPWVKdmirYnn0bY9vKG:oIHj1cYFvKFOQVT3DNmIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{NkezJO69VQ>? NIXPd3JUSU6JRWK=
SR cell MmHYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mnj2TY5pcWKrdHnvckBw\iCqdX3hckBUWiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF|LkC3OFYh|ryP M2TrOXNCVkeHUh?=
SU-DHL-1 cell NYn3c2VHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4DkbmlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjhzNUSzJO69VQ>? NEPLU4xUSU6JRWK=
SW1710 cell NULPc21rT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmrXTY5pcWKrdHnvckBw\iCqdX3hckBUXzF5MUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlM5QDl{IN88US=> M{XYOnNCVkeHUh?=
SW780 cell M3jF[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnPlTY5pcWKrdHnvckBw\iCqdX3hckBUXzd6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuPFk{PThizszN NY\SSZhTW0GQR1XS
SW872 cell M4nJUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVXJcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUSuNVQ{PSEQvF2= MkHuV2FPT0WU
SW954 cell MnK4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX;US3BIUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvQDV5OEOg{txO MlnuV2FPT0WU
T47D cell M{n4dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWPqcGh{UW6qaXLpeIlwdiCxZjDoeY1idiCWNEfEJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE42OTZ{IN88US=> M{S2PHNCVkeHUh?=
22RV1 cell M4LOcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXHKcZpqUW6qaXLpeIlwdiCxZjDoeY1idiB{MmLWNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPjF2MkSg{txO NHHqOVdUSU6JRWK=
23132-87 cell NWLnbJVuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUXJcohq[mm2aX;uJI9nKGi3bXHuJFI{OTN{LUi3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE44PTl|ODFOwG0> M4TsOXNCVkeHUh?=
639-V cell M332T2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYPlR3doUW6qaXLpeIlwdiCxZjDoeY1idiB4M{mtWkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvQDd5MzFOwG0> NH;OZ5hUSU6JRWK=
697 cell MkPUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXTRPJJIUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlE4PzR4IN88US=> NX\ZZ|F{W0GQR1XS
769-P cell NV7MbIRiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoLmTY5pcWKrdHnvckBw\iCqdX3hckA4PjlvUDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVA1QDNizszN NIrBPZJUSU6JRWK=
8-MG-BA cell NHXWUXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmnNTY5pcWKrdHnvckBw\iCqdX3hckA5NU2JLVLBJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE43OzRyMTFOwG0> NY[wTW4xW0GQR1XS
A4-Fuk cell M1rLNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFn5cpdKdmirYnn0bY9vKG:oIHj1cYFvKEF2LV\1b{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDV6MzFOwG0> NHPsNnpUSU6JRWK=
A427 cell M33wfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXnJcohq[mm2aX;uJI9nKGi3bXHuJGE1OjdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkC3Olk{KM7:TR?= MVrTRW5ITVJ?
A498 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUPJcohq[mm2aX;uJI9nKGi3bXHuJGE1QThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkC4NVM1KM7:TR?= MYTTRW5ITVJ?
AN3-CA cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXPJcohq[mm2aX;uJI9nKGi3bXHuJGFPOy2FQTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlU3OTFizszN MVnTRW5ITVJ?
AU565 cell M4fveWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFrhUIJKdmirYnn0bY9vKG:oIHj1cYFvKEGXNU[1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zOzlzNzFOwG0> M332N3NCVkeHUh?=
BB30-HNC cell M3jDZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXnlV|M1UW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwOE[0OFkh|ryP NXzvb4VlW0GQR1XS
BxPC-3 cell NFHLOHBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYXJcohq[mm2aX;uJI9nKGi3bXHuJGJ5WENvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNlI1PDJizszN MnKyV2FPT0WU
C-33-A cell MmSwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2jzbGlvcGmkaYTpc44hd2ZiaIXtZY4hSy1|Mz3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPDd6MzFOwG0> NV\LSI1PW0GQR1XS
C2BBe1 cell NH\tTFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mny3TY5pcWKrdHnvckBw\iCqdX3hckBEOkKEZUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43Pjd7IN88US=> MkPkV2FPT0WU
C3A cell M3TaS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmS5TY5pcWKrdHnvckBw\iCqdX3hckBEO0FiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkSyNVkzKM7:TR?= NVPQTpVlW0GQR1XS
CAL-33 cell M4DDbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFLLbYlKdmirYnn0bY9vKG:oIHj1cYFvKEODTD2zN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPDNzMkWg{txO MUDTRW5ITVJ?
CAL-51 cell Mon1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYXJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC13MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuOlI5PDFizqzt MVnTRW5ITVJ?
CAL-54 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm\HTY5pcWKrdHnvckBw\iCqdX3hckBESUxvNUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlg5PjJ3IN88US=> M1rUUXNCVkeHUh?=
CAL-85-1 cell NGC1TVVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3:4TWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUi1MVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02Njl3M{C5JO69VQ>? NYLaVWdOW0GQR1XS
TE-10 cell NYqzdpU1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmDCTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUmuNFQzOjVizszN MX3TRW5ITVJ?
TE-15 cell M2PKNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIPiT5FKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUG1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok41QTN7MzFOwG0> NGOxVoNUSU6JRWK=
TE-5 cell NVnsXY5IT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mmm3TY5pcWKrdHnvckBw\iCqdX3hckBVTS13IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND64NlQ2OiEQvF2= M1;IcXNCVkeHUh?=
TE-8 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn:xTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkSuOVI1OyEQvF2= MmHQV2FPT0WU
TT cell NVjyUYhjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYnJcohq[mm2aX;uJI9nKGi3bXHuJHRVKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS5|MkeyOEDPxE1? MkLUV2FPT0WU
U-118-MG cell M3j3VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXvCR45lUW6qaXLpeIlwdiCxZjDoeY1idiCXLUGxPE1OTyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTlwOUCyOVgh|ryP MYfTRW5ITVJ?
U-698-M cell Mo\3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mly1TY5pcWKrdHnvckBw\iCqdX3hckBWNTZ7OD3NJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvODBzNTFOwG0> MlHsV2FPT0WU
U251 cell NEGwdIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7TWW5KdmirYnn0bY9vKG:oIHj1cYFvKFV{NUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPU4zODRizszN M1jwR3NCVkeHUh?=
UACC-62 cell MmHtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1T1TGlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI4NjB3NEWg{txO MVTTRW5ITVJ?
UACC-893 cell NXH5dZRQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWPJcohq[mm2aX;uJI9nKGi3bXHuJHVCS0NvOEmzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU4zQTN|OTFOwG0> MWPTRW5ITVJ?
VMRC-RCZ cell NXrEV3BQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGrEd4tKdmirYnn0bY9vKG:oIHj1cYFvKF[PUlOtVmNbKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55MEm1OUDPxE1? M131OnNCVkeHUh?=
YKG-1 cell MkDkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4HlXWlvcGmkaYTpc44hd2ZiaIXtZY4hYUuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAyQDB4IN88US=> NUDoO|VMW0GQR1XS
CCF-STTG1 cell NIS1[HVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGTVWnRKdmirYnn0bY9vKG:oIHj1cYFvKEOFRj3TWHRIOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZwOEG1NFEh|ryP MWXTRW5ITVJ?
CCRF-CEM cell MmfkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2DzemlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njl|NUSxJO69VQ>? NYjvOnFWW0GQR1XS
CESS cell NHjKOW9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYfvS2RlUW6qaXLpeIlwdiCxZjDoeY1idiCFRWPTJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk44ODB6OTFOwG0> NUXZZXJKW0GQR1XS
CHP-212 cell NXzIdYJnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYDJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1{MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlU2QDZ5IN88US=> NY\EO41EW0GQR1XS
COLO-205 cell NX3iWWYzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vMkC1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU46QTdyNjFOwG0> NGfud3ZUSU6JRWK=
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CTB-1 cell NWSxdYNOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWfzeZhDUW6qaXLpeIlwdiCxZjDoeY1idiCFVFKtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPTl5NUGg{txO NEnLWGlUSU6JRWK=
Ca-Ski cell NHn0XJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGLjOIRKdmirYnn0bY9vKG:oIHj1cYFvKEOjLWPrbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvOzRzMTFOwG0> M{HDOnNCVkeHUh?=
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DSH1 cell NY\iWHA4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJGRUUDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm4O|IzKM7:TR?= NYryXVRQW0GQR1XS
DV-90 cell NVXJT3pNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYjzbXJxUW6qaXLpeIlwdiCxZjDoeY1idiCGVj25NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvODNzMkKg{txO MVTTRW5ITVJ?
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EB2 cell NIXwUm5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGXIboRKdmirYnn0bY9vKG:oIHj1cYFvKEWEMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuO|U1PjhizszN M{XwTnNCVkeHUh?=
ECC12 cell NITXNFdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVHJcohq[mm2aX;uJI9nKGi3bXHuJGVESzF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD64PFU3QSEQvF2= NFfpWXNUSU6JRWK=
EFM-19 cell M{jhbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mlz5TY5pcWKrdHnvckBw\iCqdX3hckBGTk1vMUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PDB6IN88US=> MoDQV2FPT0WU
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ES7 cell Mm\US5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWC0doFSUW6qaXLpeIlwdiCxZjDoeY1idiCHU{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlM1PTFzIN88US=> M37iOHNCVkeHUh?=
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EW-3 cell MkPWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2nQdmlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOlQ1OTRizszN NWnUcI5EW0GQR1XS
HCC70 cell NWnxT3E6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkTGTY5pcWKrdHnvckBw\iCqdX3hckBJS0N5MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuO|UxPzhizszN MmrsV2FPT0WU
HGC-27 cell NGPsWpJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGG2dGNKdmirYnn0bY9vKG:oIHj1cYFvKEiJQz2yO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTVyM{Og{txO NHTwTHFUSU6JRWK=
IGROV-1 cell NUDqO4g6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEG4VYtKdmirYnn0bY9vKG:oIHj1cYFvKEmJUl;WMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjd{M{K4JO6ddQ>? MY\TRW5ITVJ?
MDA-MB-361 cell MoLHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIHi[o1KdmirYnn0bY9vKG:oIHj1cYFvKE2GQT3NRk0{PjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkS4PVk2KM7:TR?= NHfoTVBUSU6JRWK=
MDA-MB-415 cell NXy0XWZlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXzCS4lVUW6qaXLpeIlwdiCxZjDoeY1idiCPRFGtUWIuPDF3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63N|Q1QSEQvF2= NXLi[lRbW0GQR1XS
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ME-180 cell MkfMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml;mTY5pcWKrdHnvckBw\iCqdX3hckBOTS1zOECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlE2ODFzIN8ccS=> MnfLV2FPT0WU
NCI-H526 cells M{n3V2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1XhcGlvcGmkaYTpc44hd2ZiQXv0MY1m\GmjdHXkJIFvfGmjcH;weI91cWNiYXP0bZZqfHliaX6gbJVu[W5iTlPJMWg2OjZiY3XscJMh[XO|ZYPz[YQh[XNiZHnzdpVxfGmxbjDv[kBxem:2ZXnuMWFx[WZvMTDjc41xdGW6IHH0JFUxKHWPIHHmeIVzKDJ2IHjyd{BjgSCZZYP0[ZJvKGKub4SgZY5idHm|aYO= M3jyXlE4PjB|NUSw

... Click to View More Cell Line Experimental Data

In vivo In mice, Akti-1/2 (50 mg/kg, i.p.) inhibits basal and IGF-stimulated Akt1 and Akt2 phosphorylation in lung. [1]

Protocol

Kinase Assay:[2]
+ Expand

Kinase screen:

Briefly, all assays (25.5 μl at 21°C for 30 min) are performed using a Biomek 2000 Laboratory Automation Workstation in a 96-well format. Reactions contains 5–20 mU purified kinase along with substrate peptide or protein and are initiated by the addition of 10 mM MgAcetate and 5, 20, or 50 μM ATP ([γ-33P]-ATP, 800 cpm/pmol).
Cell Research:[4 ]
+ Expand
  • Cell lines: HCC827, NCI-H522, NCI-1651, and PC-9 cells
  • Concentrations: ~10 μM
  • Incubation Time: 96 h
  • Method: The cell growth inhibitory effect of AKTi-1/2 is studied using the 96 h sulforhodamine B assay (SRB). Drug concentrations that inhibited 50% of cell growth (IC50) are calculated for each compound in GraphPad Prism 6.0 using non-linear regression analysis and sigmoidal dose–response (variable slope) equation.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 22 mg/mL (39.88 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 551.64
Formula

C34H29N7O

CAS No. 612847-09-3
Storage powder
in solvent
Synonyms Akt Inhibitor VIII

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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