Taurine

Taurine is an organic acid widely distributed in animal tissues.

Taurine Chemical Structure

Taurine Chemical Structure

CAS: 107-35-7

Purity & Quality Control

Batch: Purity: 100%
100

Taurine Related Products

Biological Activity

Description Taurine is an organic acid widely distributed in animal tissues.
In vitro
In vitro Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms. [1] In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. [2] In addition, Taurine is an essential nutrient for the cat. [3] Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function. [4]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05953064 Active not recruiting
Hypertriglyceridemia
University Hospital Gentofte Copenhagen
January 1 2023 Not Applicable
NCT04735172 Recruiting
Parkinson''s Disease
University Hospital Clermont-Ferrand
April 7 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight 125.15 Formula

C2H7NO3S

CAS No. 107-35-7 SDF Download Taurine SDF
Smiles C(CS(=O)(=O)O)N
Storage (From the date of receipt)

In vitro
Batch:

Water : 20 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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