Taurine

Catalog No.S2008

For research use only.

Taurine is an organic acid widely distributed in animal tissues.

Taurine Chemical Structure

CAS No. 107-35-7

Purity & Quality Control

Related Other Products

Biological Activity

Description Taurine is an organic acid widely distributed in animal tissues.
In vitro

Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms. [1] In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. [2] In addition, Taurine is an essential nutrient for the cat. [3] Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function. [4]

Protocol (from reference)

Solubility (25°C)

In vitro

Water 20 mg/mL
(159.8 mM)
DMSO Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 125.15
Formula

C2H7NO3S

CAS No. 107-35-7
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(CS(=O)(=O)O)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04735172 Not yet recruiting Other: specific MRI Acquisition (NMR spectroscopy) at 7T Parkinson''s Disease University Hospital Clermont-Ferrand September 2021 Not Applicable
NCT04949607 Not yet recruiting Dietary Supplement: Inulin fructooligosaccharide Brain Injury Chronic|Brain Injuries Traumatic Centre for Neuro Skills|University of Texas July 1 2021 Not Applicable
NCT04291352 Not yet recruiting Dietary Supplement: Taurine|Other: Placebo Thalassemia Major University Health Network Toronto June 1 2020 Not Applicable
NCT04047043 Completed Diagnostic Test: serum taurine Taurine Ain Shams University August 1 2019 --

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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