Taurine is evaluated across numerous clinical trials spanning Phase 1 through Phase 4 as well as non-phased protocols. These studies investigate metabolic, neurological, and physiological conditions—such as hypertriglyceridemia, Parkinson's disease, diabetes, obesity, succinic semialdehyde dehydrogenase deficiency, and sports nutritional phenomena. Sponsored by university hospitals and research institutions like the National Institute of Neurological Disorders and Stroke, the overall research landscape includes completed, recruiting, active non-recruiting, and terminated trials.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07263607 | NOT_YET_RECRUITING | Multiple Sclerosis (MS) Relapsing Remitting |
Sichuan Academy of Medical Sciences |
2026-01-01 | PHASE2 |
| NCT07771166 | NOT_YET_RECRUITING | Cardiometabolic Conditions |
University Hospital, Gentofte, Copenhagen |
2027-06 | |
| NCT07656051 | NOT_YET_RECRUITING | Type 2 Diabetes |
University of Portsmouth |
2026-06-01 | |
| NCT07682402 | NOT_YET_RECRUITING | Long COVID; Post COVID-19 Condition; PASC Post Acute Sequelae of COVID 19 |
University of Alberta |
2026-09-30 | PHASE1; PHASE2 |
| NCT06721949 | RECRUITING | Long COVID |
University of Alberta |
2025-11-18 | PHASE2; PHASE3 |
| NCT07711899 | NOT_YET_RECRUITING | Obesity (BMI>30); Metabolically Healthy Obesity; Metabolically Unhealty Obese |
University of Sao Paulo |
2026-10-01 | |
| NCT07029178 | RECRUITING | Radiation Induced Oral Mucositis; Radiodermatitis |
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University |
2025-11-24 | PHASE2 |
| NCT06847555 | RECRUITING | To Evaluate the Safety of Taurine in Preventing Acute Radiation Skin Injury Induced by Adjuvant Radiotherapy in Breast Cancer Patients |
Shandong Cancer Hospital and Institute |
2025-05-25 | PHASE1; PHASE2 |
| NCT06128252 | RECRUITING | Gastric Cancer |
Tang-Du Hospital |
2024-09-01 | |
| NCT07567742 | NOT_YET_RECRUITING | Oral Mucositis (Ulcerative) Due to Radiation; Nasopharyngeal Carcinoma (NPC) |
Sun Yat-sen University |
2026-05-06 | PHASE2 |
| NCT07144033 | NOT_YET_RECRUITING | Pain, Acute; Pain, Chronic; Chronic Post Operative Pain |
Chinese University of Hong Kong |
2026-01-01 | |
| NCT07654946 | RECRUITING | Local Muscular Endurance and Fatigue; NIRS Skeletal Muscle Mitochondrial Capacity; Acute Taurine Supplementation |
Louisiana State University and A&M College |
2026-07-15 | |
| NCT07730255 | ACTIVE_NOT_RECRUITING | Obesity (BMI>30) |
University of Sao Paulo |
2026-05-01 | |
| NCT07710547 | ACTIVE_NOT_RECRUITING | Athletic Performance; Cognitive Fatigue; Exercise Recovery; Football-Specific Performance; Perceptual-cognitive Performance |
Vizja University in Warsaw |
2026-08-06 | |
| NCT07696052 | ACTIVE_NOT_RECRUITING | Mental Fatigue; Cognitive Performance; Athletic Performance; Soccer Performance; Decision Making |
Vizja University in Warsaw |
2026-08-06 | |
| NCT06579508 | ACTIVE_NOT_RECRUITING | Obesity |
University of Sao Paulo |
2025-03-01 | |
| NCT07604519 | COMPLETED | Sports Performance; Cognitive Performance During Physical Activity; Fatigue; Recovery; Football Players |
Vizja University in Warsaw |
2026-06-14 | |
| NCT07487623 | RECRUITING | Liver Disease Chronic; HEPATITIS C VIRUS CHRONIC INFECTION |
University of Guadalajara |
2025-10-11 | |
| NCT07212803 | RECRUITING | Healthy Volunteers; Safety After Oral Intake |
University of the Pacific |
2025-11-01 | PHASE4 |
| NCT07466654 | COMPLETED | Anaerobic Performance Neuromuscular Performance Cognitive Performance |
Ankara University |
2025-10-15 | |
| NCT06613542 | COMPLETED | Taurine; Aging, Biological; Physical Activity; Metabolic Health; Anti-Aging; Longevity; Dietary Supplement; DNA Methylation; Sport |
Technical University of Munich |
2024-09-25 | |
| NCT04874012 | RECRUITING | Diabetes Mellitus, Type 2 |
Hospital de Clinicas de Porto Alegre |
2021-06-12 | PHASE2 |
| NCT07771309 | COMPLETED | Omega-3 Fatty Acids; Absorption of Omega-3; Pharmacokinetics |
University of Copenhagen |
2025-04-15 | |
| NCT06123455 | UNKNOWN | Gastric Cancer |
Tang-Du Hospital |
2023-08-01 | PHASE2 |
| NCT07580248 | COMPLETED | Physical Performance; Cognitive Performance |
Krzysztof Mizera |
2025-03-25 | |
| NCT06884566 | COMPLETED | Taurine |
University of Central Lancashire Cyprus |
2025-01-07 | |
| NCT06824571 | COMPLETED | Exercise Performance in Extreme Environments |
Xiaodong Cheng |
2024-12-01 | |
| NCT06639711 | ACTIVE_NOT_RECRUITING | Cataract |
University Of Anbar |
2023-07-10 | PHASE1; PHASE2 |
| NCT06899620 | COMPLETED | Drinking Behavior |
Wecare Probiotics Co., Ltd. |
2024-07-01 | |
| NCT04291352 | UNKNOWN | Thalassemia Major |
University Health Network, Toronto |
2020-06-01 | |
| NCT05980520 | COMPLETED | Autism Spectrum Disorder |
Guizhou Provincial People's Hospital |
2023-08-18 | |
| NCT06635369 | COMPLETED | Peridontal Disease; Aging |
Istanbul Medipol University Hospital |
2023-12-21 | |
| NCT05733364 | COMPLETED | Healthy |
Société des Produits Nestlé (SPN) |
2023-03-08 | |
| NCT05415176 | UNKNOWN | Browning of Subcutaneous White Adipose Tissue Post Intervention; Metabolic and Inflammatory Variables Post Intervention |
University of Sao Paulo |
2023-02-27 | |
| NCT05953064 | Active not recruiting | Hypertriglyceridemia |
University Hospital Gentofte Copenhagen |
2023-01-01 | Not Applicable |
| NCT05437952 | UNKNOWN | Sarcopenic Obesity |
University of Sao Paulo |
2022-07 | |
| NCT04015557 | SUSPENDED | CBS Deficiency |
Hospital de Clinicas de Porto Alegre |
2022-02-11 | PHASE1; PHASE2 |
| NCT04735172 | Recruiting | Parkinson''s Disease |
University Hospital Clermont-Ferrand |
2022-04-07 | Not Applicable |
| NCT03550885 | COMPLETED | Colorectal Cancer |
University of Illinois at Chicago |
2018-08-01 | |
| NCT04772508 | COMPLETED | Periodontitis |
Maharishi Markendeswar University (Deemed to be University) |
2020-12-01 | |
| NCT05149716 | COMPLETED | Oxidative Stress |
University of Sao Paulo |
2020-01-13 | |
| NCT03907267 | COMPLETED | Peripartum Cardiomyopathy |
Ain Shams University |
2015-01-01 | PHASE2; PHASE3 |
| NCT03410537 | UNKNOWN | Taurine; Diabetes; Lower Extremity Artery Disease |
Third Military Medical University |
2017-01 | |
| NCT03410173 | UNKNOWN | Taurine; Cognitive Decline; Diabetes Mellitus |
Third Military Medical University |
2017-01 | |
| NCT04193761 | COMPLETED | Taurine in HCC |
Ain Shams University |
2017-03-17 | |
| NCT04192539 | COMPLETED | Taurine in Cancer Colon |
Ain Shams University |
2017-01-18 | |
| NCT05342272 | COMPLETED | Xerostomia |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
2017-09-22 | PHASE3 |
| NCT01192828 | COMPLETED | Homocystinuria |
University of Colorado, Denver |
2010-01 | PHASE1; PHASE2 |
| NCT04279600 | COMPLETED | Obesity |
University of Sao Paulo |
2017-05-01 | |
| NCT03480295 | COMPLETED | Glaucoma |
Fondazione G.B. Bietti, IRCCS |
2016-12-19 | |
| NCT04646512 | COMPLETED | Obesity |
University of Sao Paulo |
2016-02-01 | |
| NCT01381354 | COMPLETED | Multiple Sclerosis |
University of Iowa |
2010-10 | PHASE1 |
| NCT03655041 | COMPLETED | Sports Nutritional Physiological Phenomena |
University of Sao Paulo |
2013-02-01 | |
| NCT02344719 | COMPLETED | Cirrhosis; Portal Hypertension |
Medical University of Vienna |
2010-10 | PHASE4 |
| NCT01816698 | COMPLETED | Prehypertension |
Zhiming Zhu |
2012-12 | PHASE3 |
| NCT02418130 | COMPLETED | Fatigue |
Daewoong Pharmaceutical Co. LTD. |
2014-10 | PHASE4 |
| NCT02535143 | COMPLETED | Hand Skill, Relative |
Riyadh Colleges of Dentistry and Pharmacy |
2014-09 | PHASE4 |
| NCT03155919 | COMPLETED | Athletic Proteinuria |
University of Sao Paulo |
2014-02 | |
| NCT01226537 | UNKNOWN | it is a Group of Metabolic Diseases in; Which a Person Has High Blood Sugar, Either; Because the Body Does Not Produce Enough Insulin,; or Because Cells do Not Respond to the Insulin That; is Produced. |
Hamad Medical Corporation |
2012-11 | PHASE1; PHASE2 |
| NCT01421979 | COMPLETED | Cardiovascular Risk |
University of Hohenheim |
2011-04 | |
| NCT01599169 | COMPLETED | Efficacy and Tolerance of B-Back® on the Burnout Syndrome |
Université Victor Segalen Bordeaux 2 |
2012-05 | |
| NCT00497978 | COMPLETED | Insulin Resistance; Elderly Patient; Oxidative Stress |
Medical Center Alkmaar |
2008-03 | |
| NCT00217165 | COMPLETED | Bipolar Disorder; Mania; Bipolar Depression |
Mclean Hospital |
2005-04 | PHASE2 |
| NCT00420823 | COMPLETED | Psychotic Disorders |
Melbourne Health |
2007-01 | PHASE2; PHASE3 |
| NCT00391001 | TERMINATED | Bipolar Disorder |
Cambridge Health Alliance |
2006-02 | PHASE1 |
| NCT00135044 | UNKNOWN | Cholestasis |
London North West Healthcare NHS Trust |
2005-06 |
(data from https://clinicaltrials.gov, updated on 2025-12-04)
Check the
Taurine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.