CAS No. 65101-87-3

Batch: Purity:99.84
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Nanchangmycin Chemical Structure
Chemical Structure
Check the Nanchangmycin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 65101-87-3
Molecular Formula

C48H80O13
Molecular Weight (MW) 889.1
SMILES CC1CC(C(OC1C2CC(C3(O2)C(C(CC(O3)C4(CCC5(O4)CC(C(C(O5)C(C)C=C(C)C(=O)C(C)CC(C)C(=O)[O-])C)O)C)OC6CCC(C(O6)C)OC)C)C)(CO)O)C.[Na+]

Ordering Information

Biological Activity

Nanchangmycin is a natural polyether antibiotic and ionophore that exhibits broad-spectrum insecticidal, nematicidal, and antiviral activities. It acts by disrupting intracellular cation homeostasis and blocking clathrin-mediated endocytosis in target cells. Downstream, nanchangmycin inhibits the entry and replication of multiple arboviruses, including Zika virus and dengue virus, while also demonstrating potent lethality against nematodes and agricultural insect pests. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 173 mg/mL (194.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 173 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.