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Cat.No. Product Name Information Product Use Citations Product Validations
S0285 Bay 41-4109 racemate BAY 41-4109 racemate (BAY41-4109 Racemic) is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM.
Nat Commun, 2021, 12(1):2114
S4199 Antazoline HCl Antazoline hydrochloride(Phenazoline hydrochloride) is a first-generation antihistamine with anticholinergic properties and is commonly used to relieve nasal congestion and in eye drops. Antazoline hydrochloride exhibits a significant inhibitory effect on HBV DNA in the Huh7 cells, with an EC50 of 2.349 μmol/L.
S0038 AB-423 AB-423, a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors, shows potent inhibition of HBV replication with EC50 of 0.08 μM - 0.27 μM and EC90 of 0.33 μM - 1.32 μM in cells. Phase 1.
E3309 Polygala Fallax Hemsl. Rhizome Extract Polygala Fallax Hemsl. Rhizome Extract is drawed from the rhizome of Polygala Fallax Hemsl., which has effects on immune function, such as anti-stress, anti-inflammatory, blood activating, lipid regulating, and in vitro inhibition of hepatitis B virus.
S0796 JNJ-632 JNJ-632 is a potent hepatitis B virus (HBV) capsid assembly modulator (CAM) with mean EC50 of 121 nM in HepG2.2.15 cells.
E0094 Morphothiadin Morphothiadin (GLS4) is a potent inhibitor on the replication of both wild-type and adefovir-resistant Hepatitis B virus (HBV) with an IC50 of 12 nM. This compound, a nucleoside analogs that target the virus polymerase, can block the HBV replication cycle and HBV-associated chronic liver diseases.
Viruses, 2024, 16(3)323
S6729 Besifovir Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.
S6453 Bicyclol Bicyclol (SY-801) is a drug that can improve liver function and inhibit HBV replication.
S8627 OSS_128167 OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. This compound has anti-viral effect in HBV transcription and replication.
Front Immunol, 2024, 15:1402834
Sci Rep, 2024, 14(1):30924
Antioxidants (Basel), 2023, 12(3)714
S1704 Emtricitabine (FTC) Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor, and its intracellular half-life is 39 h.
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
HIV Med, 2025, 26(2):285-294
Immunity, 2024, 57(12):2928-2944.e6