BChE

Other Neuronal Signaling Related Inhibitors

VEGFR EGFR c-Met PDGFR CSF-1R IGF-1R c-Kit ALK Tie-2 HER2 c-RET

Cat.No.	Product Name	Information
S0924	Pteryxin	Pteryxin ((+)-Pteryxin), a dihydropyranocoumarin derivative found in Apiaceae family, is a potent inhibitor of butyrylcholinesterase (BChE) with IC50 of 12.96 μg/ml. This compound inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages with IC50 of 20 µM. It is potential for Alzheimer's disease (AD) treatment.
S5665	Drofenine Hydrochloride	Drofenine hydrochloride is a potent competitive inhibitor of BChE. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers.
S3245	Nodakenetin	Nodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). This compound alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. It exhibits anti-tumor activity.
S3835	Loganin	Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. This compound is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
E2237	Vasicine (hydrochloride)	Vasicine hydrochloride (Peganine hydrochloride), a salt of vasicine (VAS), is a potential natural cholinesterase inhibitor. This alkaloid, isolated from Adhatoda vasica, inhibits both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).
S5511	Ethyl (triphenylphosphoranylidene) acetate	Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
E0784	MAO-B-IN-2	MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.