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ABC Transporter

Other Apoptosis Related Inhibitors

Caspase Bcl-2 p53 Ferroptosis PD-1/PD-L1 Survivin TNF-alpha MDM2/MDMX KRas IAP
Cat.No. Product Name Information Product Use Citations Product Validations
S2492 Novobiocin Sodium (Cathomycin, Albamycin) Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria.
Redox Biol, 2025, 85:103672
J Transl Med, 2025, 23(1):1079
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
Verified customer review of Novobiocin Sodium (Cathomycin, Albamycin)
S1082 Vismodegib (GDC-0449) Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Nat Commun, 2025, 16(1):5137
Nat Commun, 2025, 16(1):1092
Nat Commun, 2025, 16(1):1267
Verified customer review of Vismodegib (GDC-0449)
E7980 Fumitremorgin C Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
S1424 Prazosin HCl Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.
J Physiol Sci, 2025, 75(2):100016
J Immunother Cancer, 2024, 12(11)e009805
BMC Pharmacol Toxicol, 2020, 21(1):61
S1715 Glipizide Glipizide (CP-28720,K 4024) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
J Exp Clin Cancer Res, 2025, 44(1):294
Cell Chem Biol, 2023, S2451-9456(23)00335-5
Front Pharmacol, 2022, 13:1046269
S2119 Probucol Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
J Immunother Cancer, 2024, 12(11)e009805
Int Immunopharmacol, 2023, 116:109820
S7043 Ko143 KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2/BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM.
DSpace, 2023, 10.33540/2012
Front Oncol, 2021, 11:620907
S4166 Chlorpropamide Chlorpropamide inhibits Na(+),K(+)-ATPase and stimulates a high affinity cyclic AMP-phosphodiesterase of isolated liver plasma membrane. Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus.
Nat Commun, 2017, 8(1):573
E5770 DIDS sodium salt
E7972 Isosilybin A Isosilybin A is a flavonolignan isolated from silymarin that exhibits anti-prostate cancer (PCA) efficacy with an IC50 of 32 μM in DU145 cells. It induces growth inhibition, G1 arrest, and apoptosis in PCA cells by targeting the Akt-NF-κB-AR axis, highlighting its potential as a therapeutic agent in clinical prostate cancer (PCA) management.