Home Apoptosis Survivin

Survivin

Survivin Products

  • All (5)
  • Survivin Inhibitors (4)
  • New Survivin Products
Catalog No. Product Name Information Product Use Citations Product Validations
S1130 Sepantronium Bromide (YM155) Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.
Cell Rep Med, 2025, S2666-3791(25)00102-8
Biochim Biophys Acta Mol Basis Dis, 2025, 1871(3):167693
Cell Commun Signal, 2024, 22(1):440
F0264New Survivin Rabbit mAb
Int J Mol Sci, 2022, 23(20)12071
E1713 FL118 FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
S5600 Flavokawain A Flavokawain A, extracted from kava, is an apoptotic inducers and anticarcinogenic agent. Flavokawain A can down-regulation of antiapoptotic proteins, such as XIAP, survivin, and Bcl-xL, thereby changing the balance between apoptotic and antiapoptotic molecules and then induce cell death in tumor cells.
E0108 LQZ-7I LQZ-7I is a novel selectively inhibitor of survivin dimerization with IC50s of 4.8 µM and 3.1 µM in prostate cancer cell lines PC-3 and C4-2, respectively. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
S1130 Sepantronium Bromide (YM155) Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.
Cell Rep Med, 2025, S2666-3791(25)00102-8
Biochim Biophys Acta Mol Basis Dis, 2025, 1871(3):167693
Cell Commun Signal, 2024, 22(1):440
E1713 FL118 FL118(10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
S5600 Flavokawain A Flavokawain A, extracted from kava, is an apoptotic inducers and anticarcinogenic agent. Flavokawain A can down-regulation of antiapoptotic proteins, such as XIAP, survivin, and Bcl-xL, thereby changing the balance between apoptotic and antiapoptotic molecules and then induce cell death in tumor cells.
E0108 LQZ-7I LQZ-7I is a novel selectively inhibitor of survivin dimerization with IC50s of 4.8 µM and 3.1 µM in prostate cancer cell lines PC-3 and C4-2, respectively. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
F0264New Survivin Rabbit mAb
Int J Mol Sci, 2022, 23(20)12071

Choose Selective Survivin Inhibitors

SurvivinSignaling Pathway

Survivin信号通路图
Tags: Survivin inhibitor|Survivin agonist|Survivin activator|Survivin inducer|Survivin antagonist|Survivin signaling pathway|Survivin assay kit