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RAD51

RAD51 Products

All (6)
RAD51 Inhibitors (4)
RAD51 Activator (1)
New RAD51 Products

Catalog No.	Product Name	Information	Product Use Citations	Product Validations
S2871	T0070907	T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.	Front Pharmacol, 2025, 16:1559446 Sci Rep, 2025, 15(1):17232 Immunity, 2024, 57(10):2344-2361.e7
S1244	Amuvatinib (MP-470)	Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.	Cancer Res, 2025, 10.1158/0008-5472.CAN-24-2220 bioRxiv, 2024, 2023.11.21.568071 Microbiol Spectr, 2023, e0510522.
S8077	RI-1	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.	MedComm (2020), 2024, 5(8):e690 Cell Death Discov, 2024, 10(1):434 Int J Mol Sci, 2023, 24(3)2498
S8234	RS-1	RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.	J Biomed Sci, 2024, 31(1):68 Int J Biol Sci, 2021, 17(4):1026-1040 Chembiochem, 2021, 22(20):2957-2965
F1110	Rad51 Rabbit mAb	Rad51
S9941^New	Emzadirib	Emzadirib an inhibitor of RAD51 exhibits a reduction in RAD51 foci. Emzadirib displays significant anti-tumor activity with tumor growth inhibition in in vivo and in vitro models.
S2871	T0070907	T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.	Front Pharmacol, 2025, 16:1559446 Sci Rep, 2025, 15(1):17232 Immunity, 2024, 57(10):2344-2361.e7
S1244	Amuvatinib (MP-470)	Amuvatinib (MP-470, HPK 56) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Amuvatinib suppresses c-MET and c-RET. Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity. Phase 2.	Cancer Res, 2025, 10.1158/0008-5472.CAN-24-2220 bioRxiv, 2024, 2023.11.21.568071 Microbiol Spectr, 2023, e0510522.
S8077	RI-1	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.	MedComm (2020), 2024, 5(8):e690 Cell Death Discov, 2024, 10(1):434 Int J Mol Sci, 2023, 24(3)2498
S9941^New	Emzadirib	Emzadirib an inhibitor of RAD51 exhibits a reduction in RAD51 foci. Emzadirib displays significant anti-tumor activity with tumor growth inhibition in in vivo and in vitro models.
S8234	RS-1	RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.	J Biomed Sci, 2024, 31(1):68 Int J Biol Sci, 2021, 17(4):1026-1040 Chembiochem, 2021, 22(20):2957-2965
S9941^New	Emzadirib	Emzadirib an inhibitor of RAD51 exhibits a reduction in RAD51 foci. Emzadirib displays significant anti-tumor activity with tumor growth inhibition in in vivo and in vitro models.

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Tags: RAD51 inhibitor | RAD51 activator | RAD51 modulator