Home Immunology & Inflammation AKR1C

AKR1C

Other Immunology & Inflammation Related Inhibitors

CXCR AhR STING COX IL Receptor gp120/CD4 NOD NADPH-oxidase ROS Nrf2

Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
E8282New RJG-2051 RJG-2051 is a selective covalent SuTEx inhibitor of AKR1C3 with an IC50 of 13 nM that targets a noncatalytic tyrosine residue (Y24), effectively blocking its enzymatic activity and disrupting androgen, estrogen, and prostaglandin metabolism.
S0764 AKR1C1-IN-1 AKR1C1-IN-1 is a potent and selective inhibitor of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 4 nM, 87 nM, 4.2 μM and 18.2 μM for AKR1C1, AKR1C2, AKR1C3 and AKR1C4, respectively.
S3930 Liquiritin Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
S0468New AKR1C3-IN-1 AKR1C3-IN-1 is a highly potent inhibitor of aldo-keto reductaseAKR1C3 with an IC50 of 13 nM. It can be used in research targeting both breast and prostate cancer.