Tazobactam

Synonyms: Tazobactam acid, Tazobactamum

Tazobactam (Tazobactam acid, Tazobactamum) is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.

Tazobactam Chemical Structure

Tazobactam Chemical Structure

CAS: 89786-04-9

Purity & Quality Control

Batch: Purity: 99.97%
99.97

Tazobactam Related Products

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Biological Activity

Description Tazobactam (Tazobactam acid, Tazobactamum) is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06035055 Not yet recruiting
Bronchiectasis|Cystic Fibrosis|Pseudomonas Aeruginosa|Burkholderia Cepacia Infection
Sunshine Coast Hospital and Health Service|The Prince Charles Hospital|Mater
October 2023 Phase 4
NCT05464680 Recruiting
ARDS|SARS-CoV 2 Pneumonia
Assistance Publique Hopitaux De Marseille
November 24 2022 Not Applicable
NCT04276480 Recruiting
Enterobacteriaceae Infections
University Hospital Bordeaux
February 16 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight 300.29 Formula

C10H12N4O5S

CAS No. 89786-04-9 SDF Download Tazobactam SDF
Smiles CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 60 mg/mL ( (199.8 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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