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Florfenicol Bacterial chemical

Cat.No.S4201

Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
Florfenicol Bacterial chemical Chemical Structure

Chemical Structure

Molecular Weight: 358.21

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Quality Control

Batch: S420101 DMSO]72 mg/mL]false]Ethanol]8 mg/mL]false]Water]Insoluble]false Purity: 99.04%
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99.04

Solubility

In vitro
Batch:

DMSO : 72 mg/mL (200.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 8 mg/mL

Water : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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%
% Tween 80
% ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 358.21 Formula

C12H14Cl2FNO4S

 Storage (From the date of receipt)
CAS No. 73231-34-2 Download SDF Storage of Stock Solutions

Synonyms SCH-25298,(-)-Florfenicol Smiles CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O

Mechanism of Action

In vitro

Florfenicol is found to stimulate algal growth at concentrations of 0.5, 1.0 and 2.0 mg/L, and this compound significantly inhibits algal growth at >2.0 mg/L.
In vivo

Florfenicol administers at doses of 15 and 20 mg FFC kg(-1) bw per days for 10 days significantly reduces mortality associated with francisellosis in Nile tilapia.
References

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