Home Microbiology Antibiotics chemical Capreomycin Sulfate

research use only

Capreomycin Sulfate Antibiotics chemical

Cat.No.S4234

Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.
Capreomycin Sulfate Antibiotics chemical Chemical Structure

Chemical Structure

Molecular Weight: 750.78

Jump to

Quality Control

  • Antibiotic Titer ≥700IU/mg
  • Cited in Nature Medicine for its top-tier quality
  • COA
  • Datasheet
  • SDS

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 750.78 Formula

C25H44N14O7.H2SO4

 Storage (From the date of receipt)
CAS No. 1405-37-4 Download SDF Storage of Stock Solutions

Synonyms N/A Smiles C1CN=C(NC1C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)NC(=CNC(=O)N)C(=O)N2)CNC(=O)C(CCCN)N)CO)N)N.OS(=O)(=O)O

Mechanism of Action

In vitro
Capreomycin anchors Cu(2+) ion with an amino function of the α,β-diaminopropionic acid residue at pH around 5.
References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04239326 Completed
Tuberculosis Multidrug-Resistant
Foundation for Innovative New Diagnostics Switzerland
 April 16 2021 --
NCT02496572 Unknown status
Multidrug Resistant Tuberculosis
Medecins Sans Frontieres Netherlands|Ministry of Health Republic of Uzbekistan|Imperial College London
 September 2013 --
NCT02169141 Completed
Tuberculosis
University Medical Center Groningen|Republican Scientific and Practical Centre for Pulmonology and TB|National Institute for Public Health and the Environment (RIVM)
 November 2012 --

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.