Catalog No.S4603 Synonyms: 3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid
Molecular Weight(MW): 170.12
Gallic acid, known as powerful antioxidants, is an organic acid found in a variety of foods and herbs.
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|Description||Gallic acid, known as powerful antioxidants, is an organic acid found in a variety of foods and herbs.|
Gallic acid does not protect against H(2)O(2)-induced PC12 cell death. It reduced the viability of PC12 cells in a dose-dependent manner. Gallic acid also induces cleavage of poly (ADP-ribose) polymerase, which is strongly related to apoptosis in neurons. Gallic acid induces the phosphorylation of c-Jun N-terminal protein kinase (JNK) and the downregulation of Bcl-2 in PC12 cells. Gallic acid leads to a progressive reduction in the viability of vector-transfected PC12 cells, which is delayed in PC12 cells that overexpressed Bcl-2.
|In vivo||Gallic acid effectively protects rat erythrocytes. The antioxidant effect of the compound at the tested dosage in vivo was more prevalent than its prooxidative effects. Gallic acid has ameliorative effect on lipid peroxidation in vivo.|
|In vitro||DMSO||34 mg/mL (199.85 mM)|
|Ethanol||34 mg/mL (199.85 mM)|
|Water||7 mg/mL (41.14 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Synonyms||3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid|
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT02891538||Recruiting||Colon Cancer||The University of Texas Health Science Center at San Antonio||January 31 2017||Early Phase 1|
|NCT03194620||Completed||Healthy||University of California Davis|Mars Inc.||August 2016||Not Applicable|
|NCT03199430||Completed||EGCG Influence on Catecholamine Metabolism||Swansea University||September 2015||Phase 4|
|NCT02558933||Unknown status||Fetal Alcohol Syndrome (FAS)||Parc de Salut Mar|Fundación Mutua Madrileña||June 2015||Phase 2|Phase 3|
|NCT02015312||Completed||Light Chain (AL) Amyloidosis|Cardiac Involvement||Florian Michel|German Federal Ministry of Education and Research|University Hospital Heidelberg||April 2013||Phase 2|
|NCT01744587||Recruiting||NPC||National Health Research Institutes Taiwan|Mackay Memorial Hospital|Taichung Veterans General Hospital|National Cheng-Kung University Hospital|Chang Gung Memorial Hospital|China Medical University Hospital|National Taiwan University Hospital||April 2013||Phase 2|Phase 3|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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