Myricetin

Catalog No.S2326 Synonyms: Cannabiscetin

Myricetin Chemical Structure

Molecular Weight(MW): 318.24

Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.

Size Price Stock Quantity  
In DMSO USD 70 In stock
USD 50 In stock
USD 70 In stock
USD 120 In stock
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Biological Activity

Description Myricetin, a natural flavonoid with antioxidant and anti tumor properties, is a novel inhibitor of MEK1 activity and transformation of JB6 P+ mouse epidermal cells. It also inhibits PI3Kγ with Kd of 0.17 μM.
Targets
MEK1 [4] PI3Kγ [5]
0.17 μM(Kd)
In vitro

Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. [1] Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer. [2] [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HT-29 cells NGLLSVhHfW6ldHnvckBie3OjeR?= M2TLTWRme2Wwc3n0bZpifGmxbjDv[kBIWFJ|NTDy[YNmeHSxcjDpckBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyCrbnjpZol1cW:wIH;mJJpieHKrbnHzeE1qdmS3Y3XkJIR6dmGvaXOgcYF{eyC{ZXTpd5RzcWK3dHnvckBi\nSncjCxNEBucW6|LDDJR|UxRTJwMUKg{txO MkfjNlQ6ODB2NEe=
HeLa cells MmnNSpVv[3Srb36gZZN{[Xl? NWjKWFd1UW6qaXLpeIlwdiCxZjDNVnAyKHS{YX7z[oVkfGWmIHnuJIh2dWGwIFjlUIEh[2WubIOgZZN{\XO|ZXSgZZMhcW6qaXLpeIlwdiCxZjDbN2heVFSFNDD0doFve3CxcoSgZpkhemGyaXSg[oltfHKjdHnvckBie3OjeTygT4k:Oi52IN88US=> NEW0SnMyQTd{NUW3PC=>
HCT116 cells MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGrIenc1QCCq MWLHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDIR3QyOTZiY3XscJMhd3[ncnX4dJJme3OrbnegVGk{U2GucHjhJGgyODR5UjDteZRidnRiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NF01NjFizszN M2rre|IzOjF{N{Kx
human 22Rv1 cells MXvQdo9tcW[ncnH0bY9vKGG|c3H5 NWrIS3VpOTR2IHi= NXvFS|M5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjCyNnJ3OSClZXzsd{BqdmO3YnH0[YQhfXBidH:gNVQ1KGi{czDifUBEd3WudHXyJJBienSrY3zlJINwfW62IHHu[EB{cXqnIHHuZYx6gmW{LDDJR|UxRTF|LkGg{txO M3\nOFIzPzh7OEGy
human SKBR3 cells NYDSV5RXTnWwY4Tpc44h[XO|YYm= MkLKNlQhcA>? MXzEbZNxdGGlZX3lcpQhd2ZiR12tZ5k{SiCocn;tJGh{eDlyIHnuJIh2dWGwIGPLRnI{KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDmcJVwemW|Y3XuZ4UheG:uYYLpfoF1cW:wIHHzd4F6NCCLQ{WwQVE{NjVizszN NHPFOYozPDV2OEKwOy=>
human U2OS cells NGTQUYZHfW6ldHnvckBie3OjeR?= NVnUV3R1PSCq NX;4fpA2SWexbnnzeEBi[3Srdnn0fUBifCCJUGKzOUBz\WOncITvdkBqdiCqdX3hckBWOk:VIHPlcIx{KGOxZYjwdoV{e2mwZzDHZYw1NV[SMU[tWGVXKGG|c3Xzd4VlKGG|IHLleIEh[XK{ZYP0bY4hfHKjboPsc4NifGmxbjDh[pRmeiB3IHjyd{BjgSCkZYThJIxi[3SjbXHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCHQ{WwQVE1NjdizszN MmPONlQ6ODB2NEe=
human H9 cells M3rvbmZ2dmO2aX;uJIF{e2G7 MmjTN{Bl[Xm| MmPFRY51cX[rcnHsJIFkfGm4aYT5JIFo[Wmwc4SgTGlXOSB|QjDpcoZm[3SnZDDpckBpfW2jbjDIPUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oII\pdoFtKHKncHzpZ4F1cW:wIHHmeIVzKDNiZHH5d{BjgSCyMkSgZY51cWenbjDjZZB1fXKnIHHzd4F6NCCHQ{WwQVM2KM7:TR?= NXXReFVFQDF3OEG2OC=>
NCI-60 human tumor cell line NU\QSZFnS3m2b4TvfIlkcXS7IHHzd4F6 MW\JckB3cXS{bzDjfZRwfG:6aXOgdI91\W6leTDh[4FqdnO2IF7DTU03OCCqdX3hckB1fW2xcjDj[YxtKGyrbnWsJGdKPTB;M{[g{txO NFv3Z3M6PjN{M{[2
human HL60 cells MmjqVJJwdGmoZYLheIlwdiCjc4PhfS=> M3q2flMxKM7:TR?= MnvpOFghcA>? NEj2[VhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgZZQhOzBidV2gZYZ1\XJiNEigbJJ{KGK7IF3UV{Bie3OjeR?= NXroWm9rOTh{NUi0OFA>
mouse L929 cells MX7GeY5kfGmxbjDhd5NigQ>? MVGyJIg> NUnQd4JzUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDUUmYu[WyyaHGtbY5lfWOnZDDjfZRwfG:6aXPpeJkhd2ZibX;1d4UhVDl{OTDj[YxteyCjc4Pld5Nm\CCjczDzeZJ3cX[jbHn0fUB1emWjdHXkJJdqfGhiZIL1[{Bi\nSncjCyJIhzeyCxZjDUUmZidHCqYTD0doVifG2nboS= NYmwO|d6QTJ6N{SxOS=>

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 63 mg/mL (197.96 mM)
Ethanol 9 mg/mL warmed (28.28 mM)
Water Insoluble
In vivo Add solvents individually and in order:
4% DMSO+30% PEG 300+ddH2O
5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 318.24
Formula

C15H10O8

CAS No. 529-44-2
Storage powder
Synonyms Cannabiscetin

Bio Calculators

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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MEK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID