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Technical Data
| Formula | C29H36O15 |
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| Molecular Weight | 624.59 | CAS No. | 11013-97-1 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (160.1 mM) | |
| Water | 100 mg/mL (160.1 mM) | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin. | ||
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| Targets |
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| In vitro | Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin and methyl hesperidin reduce TNF-alpha-induced VCAM-1 expression through inhibiting the phosphorylation of Akt and PKC. [1] Methyl hesperidin can bind to buman serum albumin (BSA) with binding constants between 18 and 34 mM/L. [2] Long-term carcinogenicity study demonstrates that methyl hesperidin shows no carcinogenicity for B6C3F1 mice in the 96-wk feeding regimen. [3] |
Protocol (from reference)
References
RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.