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FAAH Inhibitors (4)


Cat.No. Product Name Information Product Use Citation Customer Product Validation
S2631 URB597 URB597 is a potent, orally bioavailable FAAH inhibitor with IC50 of 4.6 nM, with no activity on other cannabinoid-related targets. Phase 1.
S2666 PF-3845 PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
S2377 Biochanin A Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 μM.
S2828 JNJ-1661010 JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.

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Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S2631 URB597 <1 mg/mL 68 mg/mL 5 mg/mL
S2666 PF-3845 <1 mg/mL 91 mg/mL 91 mg/mL
S2377 Biochanin A <1 mg/mL 57 mg/mL 9 mg/mL
S2828 JNJ-1661010 <1 mg/mL 36 mg/mL <1 mg/mL
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