SMN antagonist | SMN inhibitor | SMN agonist

Other DNA Damage/DNA Repair Related Inhibitors

HDAC PARP WRN Sirtuin Topoisomerase Telomerase DNA/RNA Synthesis MTH1 DNA alkylator High-mobility Group

Isoform-selective Products

SMN2

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S6642	Branaplam (LMI070)	Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.	EMBO Mol Med, 2023, 15(11):e17810 Commun Biol, 2021, 4(1):1374
S6925	Risdiplam	Risdiplam is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!	Science, 2023, 380(6642):eadg6518

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S6642

Branaplam (LMI070)

Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.

EMBO Mol Med, 2023, 15(11):e17810

Commun Biol, 2021, 4(1):1374

S6925

Risdiplam

Risdiplam is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!

Science, 2023, 380(6642):eadg6518