SMN antagonist | SMN inhibitor | SMN agonist

Other DNA Damage/DNA Repair Related Inhibitors

HDAC PARP WRN Sirtuin Topoisomerase Telomerase DNA/RNA Synthesis MTH1 DNA alkylator High-mobility Group

Isoform-selective Products

SMN2

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S6642	Branaplam (LMI070)	Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.	EMBO Mol Med, 2023, 15(11):e17810 EMBO Molecular Medicine, 2023, e17810 Commun Biol, 2021, 4(1):1374
S6925	Risdiplam	Risdiplam is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!	Science, 2023, eadg6518 Science, 2023, 380(6642):eadg6518

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S6642

Branaplam (LMI070)

Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.

EMBO Mol Med, 2023, 15(11):e17810

EMBO Molecular Medicine, 2023, e17810

Commun Biol, 2021, 4(1):1374

S6925

Risdiplam

Risdiplam is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!

Science, 2023, eadg6518

Science, 2023, 380(6642):eadg6518