SMN2 Selective Modulators

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S6925 Risdiplam (RG7916) Risdiplam (Evrysdi, RG7916, RO7034067) is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully! Selective
S6642 Branaplam (LMI070) Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM. Selective SMN2, EC50: 0.02 μM