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Vitexin-2-O-rhaMnoside

Cat.No.S5460

Vitexin-2-O-rhamnoside (2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside) is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge. var major N. E. Br. It has many biological and pharmacological activities, such as antioxidation and treating heart disease.
Vitexin-2-O-rhaMnoside Chemical Structure

Chemical Structure

Molecular Weight: 578.52

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Quality Control

Batch: S546001 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 99.77%
99.77

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (172.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Chemical Information, Storage & Stability

Molecular Weight 578.52 Formula

C27H30O14

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 64820-99-1 -- Storage of Stock Solutions

Synonyms 2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside Smiles CC1C(C(C(C(O1)OC2C(C(C(OC2C3=C(C=C(C4=C3OC(=CC4=O)C5=CC=C(C=C5)O)O)O)CO)O)O)O)O)O

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01199250 Not yet recruiting
Lynch Syndrome|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer
Gynecologic Oncology Group|National Cancer Institute (NCI)|GOG Foundation
 January 2100 --
NCT04598516 Withdrawn
Acute Kidney Injury (Nontraumatic)|Contrast-induced Nephropathy|Renal Insufficiency
Maastricht University Medical Center
 November 1 2097 --
NCT05454306 Suspended
Clavicle Fracture
University of Minnesota
 January 9 2028 Not Applicable
NCT04795856 Not yet recruiting
Mitral Valve Regurgitation
University of Alabama at Birmingham
 June 18 2027 Early Phase 1
NCT06359262 Not yet recruiting
Mental Health Wellness 1
Karolinska Institutet
 January 1 2027 Not Applicable

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