trans-Aconitic acid

Catalog No.S3090 Synonyms: TAA

For research use only.

trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

trans-Aconitic acid Chemical Structure

CAS No. 4023-65-8

Purity & Quality Control

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Biological Activity

Description

trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 35 mg/mL
(201.02 mM)
Water 35 mg/mL
(201.02 mM)
Ethanol '''35 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 174.11
Formula

C6H6O6

CAS No. 4023-65-8
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

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% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04925570 Not yet recruiting Device: W-SUDs|Other: Education Only Alcohol Use Disorder (AUD)|Substance Use Disorders Woebot Labs Inc.|Stanford University September 29 2021 Phase 2
NCT04707911 Not yet recruiting Behavioral: Social Media Intervention Vaping University of California San Francisco|Tobacco Related Disease Research Program|HopeLab Foundation August 15 2021 Not Applicable
NCT04974645 Not yet recruiting Device: W-SUDs|Other: Education Only Alcohol Use Disorder (AUD)|Substance Use Disorders Woebot Labs Inc.|Stanford University August 31 2021 Phase 2
NCT04335890 Recruiting Biological: Vaccination with IKKb matured Dendritic Cells Melanoma Uveal Metastatic Hasumi International Research Foundation June 24 2020 Phase 1

(data from https://clinicaltrials.gov, updated on 2021-09-06)

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