trans-Aconitic acid

Synonyms: TAA

trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

trans-Aconitic acid Chemical Structure

trans-Aconitic acid Chemical Structure

CAS: 4023-65-8

Purity & Quality Control

Batch: S309001 DMSO] 35 mg/mL] false] Water] 35 mg/mL] false] Ethanol] 35 mg/mL] false Purity: 99.57%
99.57

trans-Aconitic acid Related Products

Biological Activity

Description

trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05134740 Recruiting
Hodgkins Lymphoma|Non Hodgkins Lymphoma
Baylor College of Medicine|Center for Cell and Gene Therapy Baylor College of Medicine
January 2024 Phase 1
NCT05812027 Recruiting
Head and Neck Cancer|Cervical Cancer|Non Small Cell Lung Cancer|Melanoma|Ovarian Cancer|HPV16 Related Cancers
TScan Therapeutics Inc.
June 26 2023 --
NCT05844618 Recruiting
Atopic Dermatitis
Innovaderm Research Inc.
May 9 2023 Phase 4
NCT05705193 Recruiting
Post-Acute COVID-19 Syndrome
UConn Health
April 7 2023 Not Applicable
NCT05743920 Not yet recruiting
Depression Anxiety|Stress
Chinese University of Hong Kong
February 2023 Not Applicable

Chemical Information & Solubility

Molecular Weight 174.11 Formula

C6H6O6

CAS No. 4023-65-8 SDF --
Smiles OC(=O)C\C(=C/C(O)=O)C(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 35 mg/mL ( (201.02 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 35 mg/mL

Ethanol : 35 mg/mL


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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