CAS No. 4023-65-8
Batch:
Purity:99.57
Chemical Structure
Check the
trans-Aconitic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 4023-65-8 | |
|---|---|---|
| Molecular Formula |
C6H6O6 |
|
| Molecular Weight (MW) | 174.11 | |
| SMILES | OC(=O)C\C(=C/C(O)=O)C(O)=O |
trans-Aconitic acid is a naturally occurring plant constituent and metabolic organic acid that acts as an inhibitor of aconitase within the tricarboxylic acid (TCA) cycle. By interfering with aconitase activity and metabolic intermediate conversion, it modulates cellular energy metabolism and organic acid transport. Furthermore, as an active constituent of Echinodorus grandiflorus, trans-aconitic acid contributes to anti-inflammatory signaling and suppresses inflammatory responses associated with rheumatoid arthritis model systems.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
35 mg/mL
(201.02 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 35 mg/mL |
| Ethanol | 35 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- trans-Aconitic acid Clinical Trials
- trans-Aconitic acid Solubility in DMSO
- trans-Aconitic acid Stock Solution
- trans-Aconitic acid Storage
- trans-Aconitic acid Stability
- trans-Aconitic acid Molecular Weight
- trans-Aconitic acid SMILES
- trans-Aconitic acid Chemical Structure (2D and 3D)
- trans-Aconitic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.