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Tranexamic Acid

Cat.No.S1875

Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
Tranexamic Acid Chemical Structure

Chemical Structure

Molecular Weight: 157.21

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Quality Control

Batch: Purity: >97%
97

Solubility

In vitro
Batch:

Water : 31 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 157.21 Formula

C8H15NO2

 Storage (From the date of receipt)
CAS No. 1197-18-8 Download SDF Storage of Stock Solutions

Synonyms Transamin SMILES C1CC(CCC1CN)C(=O)O

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2025-12-15)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04387305 NOT_YET_RECRUITING
Brain Injuries, Traumatic; Wounds and Injury; Hemorrhage; Trauma Injury
Daniel Nishijima, MD, MAS
 2026-10-01 PHASE3
NCT06718751 NOT_YET_RECRUITING
Chronic Subdural Hematoma
Baylor College of Medicine
 2025-10 PHASE2
NCT07116395 NOT_YET_RECRUITING
Patients Undergoing Operative Fixation of Long Bone Fractures Within the Community Medical Centers System
Arbi Nazarian, MD
 2027-01-01 PHASE4
NCT07494032 NOT_YET_RECRUITING
Knee Arthropathy
NYU Langone Health
 2026-05-01
NCT03582293 RECRUITING
Hematoma, Subdural, Chronic
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
 2018-06-19 PHASE3
NCT06270407 RECRUITING
Surgical Complication
St. Olavs Hospital
 2024-09-18 PHASE4

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