Quinupristin

Quinupristin, a streptogramin antibiotic, blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits.

Quinupristin Chemical Structure

Quinupristin Chemical Structure

CAS: 120138-50-3

Purity & Quality Control

Batch: E081801 Ethanol] 100 mg/mL] false] DMSO] 50 mg/mL] false] Water] Insoluble] false Purity: 98.11%
98.11

Quinupristin Related Products

Biological Activity

Description Quinupristin, a streptogramin antibiotic, blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits.

Chemical Information & Solubility

Molecular Weight 1022.22 Formula

C53H67N9O10S

CAS No. 120138-50-3 SDF --
Smiles CCC1NC(=O)C(NC(=O)C2=C(O)C=CC=N2)C(C)OC(=O)C(NC(=O)C3CC(=O)C(CSC4CN5CCC4CC5)CN3C(=O)C(CC6=CC=C(C=C6)N(C)C)N(C)C(=O)C7CCCN7C1=O)C8=CC=CC=C8
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Ethanol : 100 mg/mL

DMSO : 50 mg/mL ( (48.91 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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