CAS No. 120138-50-3
Batch:
Purity:98.11
Chemical Structure
Check the
Quinupristin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 120138-50-3 | |
|---|---|---|
| Molecular Formula |
C53H67N9O10S |
|
| Molecular Weight (MW) | 1022.22 | |
| SMILES | CCC1NC(=O)C(NC(=O)C2=C(O)C=CC=N2)C(C)OC(=O)C(NC(=O)C3CC(=O)C(CSC4CN5CCC4CC5)CN3C(=O)C(CC6=CC=C(C=C6)N(C)C)N(C)C(=O)C7CCCN7C1=O)C8=CC=CC=C8 |
Quinupristin is a semisynthetic streptogramin B antibiotic that targets the 50S subunit of the bacterial ribosome. Upon binding within the ribosomal exit tunnel, it blocks peptide bond synthesis and prevents the extension of nascent polypeptide chains. This action promotes the premature detachment of incomplete protein chains, inhibiting bacterial protein synthesis and disrupting bacterial cell growth. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 100 mg/mL |
| DMSO |
50 mg/mL
(48.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.