Protoporphyrin IX

Catalog No.S5145 Synonyms: PPIX

For research use only.

Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.

Protoporphyrin IX Chemical Structure

CAS No. 553-12-8

Selleck's Protoporphyrin IX has been cited by 3 Publications

Purity & Quality Control

Related Other Products

Biological Activity

Description Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 562.66
Formula

C34H34N4O4

CAS No. 553-12-8
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C=C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05308472 Not yet recruiting Drug: DISC-1459|Drug: Placebo Erythropoietic Protoporphyria Disc Medicine Inc June 2022 Phase 2
NCT05370508 Not yet recruiting Combination Product: SONALA-001 (ALA) and Exablate device Recurrent GBM SonALAsense Inc. June 2022 Phase 2
NCT05020912 Recruiting Drug: ALA|Procedure: PDT Basal Cell Carcinoma Case Comprehensive Cancer Center November 9 2021 Phase 2
NCT05101798 Recruiting Drug: 5-Aminolevulinic acid Hydrochloride Neoplasm|Skull Base Neoplasm Icahn School of Medicine at Mount Sinai|NX Development Corp September 14 2021 Phase 2

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Protoporphyrin IX | Protoporphyrin IX supplier | purchase Protoporphyrin IX | Protoporphyrin IX cost | Protoporphyrin IX manufacturer | order Protoporphyrin IX | Protoporphyrin IX distributor