Protoporphyrin IX (PPIX)

Name: Protoporphyrin IX (PPIX)
Brand: Selleck Chemicals
SKU: S5145
Rating: 5 (4 reviews)

Catalog No.S5145 Purity: 99.02%

Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.

Protoporphyrin IX (PPIX) Chemical Structure

CAS: 553-12-8

Selleck's Protoporphyrin IX (PPIX) has been cited by 4 publications

Purity & Quality Control

Batch: Purity: 99.02%

99.02

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Biological Activity

Description	Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05883748	Not yet recruiting	Erythropoietic Protoporphyria	Disc Medicine Inc	September 2023	Phase 2\|Phase 3
NCT05308472	Active not recruiting	Erythropoietic Protoporphyria	Disc Medicine Inc	October 31 2022	Phase 2

Chemical Information & Solubility

Molecular Weight	562.66	Formula	C₃₄H₃₄N₄O₄
CAS No.	553-12-8	SDF	Download Protoporphyrin IX (PPIX) SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (177.72 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble

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In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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