Paroxetine mesylate

For research use only.

Catalog No.S5239

1 publication

Paroxetine mesylate Chemical Structure

CAS No. 217797-14-3

Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.

Selleck's Paroxetine mesylate has been cited by 1 publication

Purity & Quality Control

Choose Selective Serotonin Transporter Inhibitors

Biological Activity

Description Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.

Protocol

References

Solubility (25°C)

In vitro DMSO 85 mg/mL (199.77 mM)
Ethanol '-1 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 425.47
Formula

C19H20FNO3.CH4O3S

CAS No. 217797-14-3
Storage powder
in solvent
Synonyms N/A
Smiles CS(=O)(=O)O.C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4

In vivo Formulation Calculator (Clear solution)

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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01829919 Completed Drug: Brisdelle (paroxetine mesylate) Postmenopausal Symptoms Noven Therapeutics July 2011 Phase 1
NCT01361308 Completed Drug: Brisdelle (paroxetine mesylate)|Drug: Placebo capsules Postmenopausal Symptoms Noven Therapeutics May 2011 Phase 3
NCT01101841 Completed Drug: Brisdelle (paroxetine mesylate)|Drug: Placebo capsules Hot Flashes Noven Therapeutics March 2010 Phase 3
NCT00786188 Completed Drug: Brisdelle (paroxetine mesylate)|Drug: Sugar pill Hot Flashes Noven Therapeutics November 2008 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID