OTX008

Catalog No.S6949 Synonyms: Calixarene 0118, PTX-008

For research use only.

OTX008 (Calixarene 0118, PTX008), a calixarene derivative, is a selective inhibitor of galectin-1 (Gal1) with anti-tumoural activity.

OTX008 Chemical Structure

CAS No. 286936-40-1

Purity & Quality Control

Choose Selective Galectin Inhibitors

Biological Activity

Description OTX008 (Calixarene 0118, PTX008), a calixarene derivative, is a selective inhibitor of galectin-1 (Gal1) with anti-tumoural activity.
Targets
galectin-1 [1]
()

Protocol (from reference)

Solubility (25°C)

In vitro

Ethanol 50 mg/mL
(53.35 mM)
DMSO 3 mg/mL
(3.2 mM)
Water Insoluble

Chemical Information

Molecular Weight 937.18
Formula

C52H72N8O8

CAS No. 286936-40-1
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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