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Galectin

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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S0471 Olitigaltin (TD139) Olitigaltin (TD-139, GB0-139) is a potent and selective inhibitor of galectin-3 with Kd of 0.036 µM over galectin-1 and galectin-7 with Kd of 2.2 µM and 32 µM, respectively. TD-139 is used potentially for the treatment of idiopathic pulmonary fibrosis (IPF).
bioRxiv, March 14, 2025, 2025.03.12.642905
Frontiers in Allergy, February 28, 2022, 840454
Nat Commun, 2025, 16(1):2419
S6949 OTX008 OTX008 (Calixarene 0118, PTX008), a calixarene derivative, is a selective inhibitor of galectin-1 (Gal1) with anti-tumoural activity.
Cancer Res, November 15, 2024, 3894-3908
Molecules, July 26, 2022, 4785
Biochem Pharmacol, 2024, 229:116474
S8834 GB1107 GB1107 is a potent, selective, inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3.
Mater Today Bio, 2025, 32:101801
BMC Musculoskelet Disord, 2024, 25(1):249