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MOCAc-PLGL(Dpa)AR Dyes chemical

Name: MOCAc-PLGL(Dpa)AR
Brand: Selleck Chemicals
SKU: E6756
Availability: InStock
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Cat.No.E6756

MOCAc-PLGL(Dpa)AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂) is a FRET-based fluorescent peptide substrate for MMPs including MMP-7 (matrilysin), MMP-2, and MMP-9, where the MOCAc fluorophore is quenched by Dpa until cleavage at the Gly-Leu bond produces >10-fold fluorescence increase for activity assays.

Chemical Structure

Molecular Weight: 1093.15

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SDS/MSDS
Datasheet

Related Targets	PROTAC Others Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Dyes Inhibitors	Fluorofurimazine (FFz) CFSE (CFDA-SE) Propidium Iodide DFO Thiazolyl Blue Hoechst 33342 D-Luciferin Crystal Violet D-Luciferin sodium salt Dihydroethidium

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Chemical Information, Storage & Stability

Molecular Weight	1093.15	Formula	C₄₉H₆₈N₁₄O₁₅	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	140430-53-1	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/12801907/ [2] https://pubmed.ncbi.nlm.nih.gov/15113693/ [3] https://pubmed.ncbi.nlm.nih.gov/15322372/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2025-12-08)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07017010	RECRUITING	Reading Difficulties	Ohio State University	2025-09-12
NCT06714357	RECRUITING	Colorectal Cancer Metastatic	National Cancer Institute, Naples	2025-03-12	PHASE2
NCT07572500	WITHDRAWN	Hypoxia; OSA; Obesity	Stanford University	2025-11
NCT07023068	ENROLLING_BY_INVITATION	Lung Cancers	Peking Union Medical College Hospital	2024-09-28	EARLY_PHASE1
NCT05757765	NOT_YET_RECRUITING	Sarcopenia	Zuyderland Medisch Centrum	2023-02-27
NCT03689114	COMPLETED	Epilepsies, Partial	Mario Negri Institute for Pharmacological Research	2021-05-10	PHASE4

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