CAS No. 140430-53-1
Chemical Structure
Check the
MOCAc-PLGL(Dpa)AR
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | (2S)-N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(2,4-dinitroanilino)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]-1-[2-(7-methoxy-2-oxochromen-4-yl)acetyl]pyrrolidine-2-carboxamide | |
|---|---|---|
| CAS Number | 140430-53-1 | |
| Molecular Formula |
C49H68N14O15 |
|
| Molecular Weight (MW) | 1093.15 | |
| InChIKey | RQASLOJQHHELIQ-QJSKOQLASA-N |
Biological Activity
MOCAc-PLGL(Dpa)AR is a fluorogenic FRET peptide substrate for matrix metalloproteinases (MMPs), including MMP-2, MMP-7, and MMP-9. Cleavage of the Gly-Leu peptide bond by MMPs separates the (7-methoxycoumarin-4-yl)acetyl fluorophore from the 2,4-dinitrophenyl quencher group. This enzymatic processing produces a strong fluorescence signal increase, enabling real-time fluorometric assays to monitor matrix metalloproteinase cleavage kinetics and catalytic activity. [1]
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Note: Technical data last updated: Sep 1, 2026.