KB-R7943 mesylate

Catalog No.S4643

For research use only.

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCX(rev)) with IC50 of 5.7 μM. KB-R7943 mesylate promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux.

KB-R7943 mesylate Chemical Structure

CAS No. 182004-65-5

Purity & Quality Control

Choose Selective NCX Inhibitors

Biological Activity

Description KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCX(rev)) with IC50 of 5.7 μM. KB-R7943 mesylate promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux.
Targets
NCX(rev) [1]
(Cell-free assay)
5.7 μM

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 86 mg/mL
(201.16 mM)
Water Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 427.5
Formula

C17H21N3O6S2

CAS No. 182004-65-5
Storage 3 years -20°C powder
2 years -80°C in solvent

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