Isosulfan Blue | Dyes chemical | Highly Cited | In Stock

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Batch: E000701 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]5 mg/mL]false Purity: 99.95%

Cited in Nature Medicine for its top-tier quality
COA
SDS/MSDS
Datasheet

99.95

Related Targets	PROTAC Others Antineoplastic and Immunosuppressive Antibiotics ADC Cytotoxin Selection Antibiotics for Transfected Cell Antibiotics for Mammalian Cell Culture ADC Linker Molecular Glues Hydrotropic Agents Antibiotics for Plant Cell Culture
Other Dyes Inhibitors	Fluorofurimazine (FFz) CFSE (CFDA-SE) Propidium Iodide DFO Thiazolyl Blue Hoechst 33342 D-Luciferin Crystal Violet D-Luciferin sodium salt Dihydroethidium

Solubility

In vitro
Batch:

DMSO : 100 mg/mL (176.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 100 mg/mL

Ethanol : 5 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	566.66	Formula	C₂₇H₃₁N₂NaO₆S₂	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	68238-36-8	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	Lymphazurin dye			SMILES	[Na+].CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(C=C2)=[N+](CC)CC)C3=C(C=CC(=C3)[S]([O-])(=O)=O)[S]([O-])(=O)=O

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

References	[1] https://ascopubs.org/doi/abs/10.1200/JCO.2018.36.15_suppl.e12617

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-04-21)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT03927027	ACTIVE_NOT_RECRUITING	Breast Cancer Stage I; Breast Cancer Stage II; Breast Cancer Stage III	Alliance for Clinical Trials in Oncology	2019-07-29	PHASE3
NCT07269860	COMPLETED	Breast Cancer	University of Arizona	2025-07-09
NCT05663112	COMPLETED	Sentinel Lymph Node; Breast Cancer	Manisa Celal Bayar University	2021-12-06
NCT05859971	COMPLETED	Breast Cancer	University of Wisconsin, Madison	2023-04-13	EARLY_PHASE1
NCT01818739	COMPLETED	Endometrial Cancer	Ohio State University Comprehensive Cancer Center	2013-03
NCT01939028	TERMINATED	Stage I Endometrial Carcinoma; Stage II Endometrial Carcinoma; Stage III Endometrial Carcinoma; Stage IV Endometrial Carcinoma	Case Comprehensive Cancer Center	2013-07

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Isosulfan Blue Dyes chemical

Chemical Structure

Molecular Weight: 566.66