Insulin (human)

Synonyms: Insulin regular

Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.

Insulin (human) Chemical Structure

Insulin (human) Chemical Structure

CAS: 11061-68-0

Selleck's Insulin (human) has been cited by 5 publications

Purity & Quality Control

Batch: Purity: 99.99%
99.99

Insulin (human) Related Products

Signaling Pathway

Choose Selective IGF-1R Inhibitors

Biological Activity

Description Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.
In vitro
In vitro

Insulin, an inducer of AKT phosphorylation, reduces the levels of LC3-II, VP1 by the AKT-AMPKMAPK-MTOR pathway in SVV-infected cells.[2]

Cell Research Cell lines BHK-21 cells and PK-15 cells
Concentrations 200 ng/ml
Incubation Time 1 h
Method

BHK-21 cells and PK-15 cells are grown to 80% confluence in well plates and pretreated with insulin (200 ng/ml) for 1 h. The pretreated cells are then infected with SVV for 1 h. The cells are then washed with phosphate-buffered saline (PBS) and incubated with new medium containing the same chemical reagents. Cell viability in the presence of chemical reagents is tested.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04523363 Not yet recruiting
Prediabetes; Complicating Pregnancy
Gianna Wilkie|University of Massachusetts Worcester
January 1 2025 Phase 4
NCT05083546 Not yet recruiting
Obesity|Aging
University of California San Francisco
December 1 2024 Phase 1|Phase 2

Chemical Information & Solubility

Molecular Weight 5807.57 Formula

C257H383N65O77S6

CAS No. 11061-68-0 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

0.01M HCl : 13 mg/mL

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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