Insulin (human)

Catalog No.S6955 Synonyms: Insulin regular

For research use only.

Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.

Insulin (human) Chemical Structure

CAS No. 11061-68-0

Selleck's Insulin (human) has been cited by 1 Publication

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Biological Activity

Description Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 100 mg/mL
(17.21 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 5807.57
Formula

C257H383N65O77S6

CAS No. 11061-68-0
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05006040 Not yet recruiting Device: Hybrid Closed Loop System High Risk Acute Lymphoblastic Leukemia University of Colorado Denver|Children''s Hospital Colorado|DexCom Inc.|Tandem Diabetes Care Inc.|National Cancer Institute (NCI) December 1 2022 Early Phase 1
NCT03998293 Not yet recruiting Drug: Somatostatin Healthy Mayo Clinic|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) November 1 2022 Phase 4
NCT04589325 Not yet recruiting Drug: Ixekizumab|Drug: Placebo Type1 Diabetes Mellitus Vastra Gotaland Region|Eli Lilly and Company|Gothia Forum - Center for Clinical Trial|Statistiska Konsultgruppen|Karolinska University Laboratory September 2022 Phase 2
NCT04169243 Not yet recruiting Behavioral: New Nordic Diet|Other: Control Gestational Diabetes Mellitus Göteborg University|Swedish Council for Working Life and Social Research September 2022 Not Applicable
NCT04088981 Not yet recruiting Behavioral: Dietary intervention Diabetes Mellitus Type 2 Physicians Committee for Responsible Medicine|Yale University July 2022 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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