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Insulin (human) Polypeptide

Name: Insulin (human)
Brand: Selleck Chemicals
SKU: S6955
Availability: InStock
Rating: 5 (12 reviews)

Cat.No.S6955

Insulin (human) (Insulin regular) is a polypeptide hormone that regulates the level of glucose. Insulin is commonly used to treat hyperglycemia in patients with diabetes. Potency: 29 units/mg.

Insulin (human) IGF-1R modulator Chemical Structure

Quality Control

Batch: Purity: 99.99%

99.99

Related Targets	EGFR VEGFR FGFR PDGFR c-Met Src MEK CSF-1R FLT3 HER2
Other IGF-1R Inhibitors	Linsitinib (OSI-906) BMS-536924 NVP-AEW541 BMS-754807 Picropodophyllin (AXL1717) AG-1024 GSK1904529A NVP-ADW742 NT157 PQ 401

Solubility

In vitro
Batch:

0.01M HCl : 13 mg/mL

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.500mg/ml (0.43mM)	Taking the 1 mL working solution as an example, add 50 μL of 50 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	0.400mg/ml (0.07mM)	Taking the 1 mL working solution as an example, add 50 μL of 8 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	5807.57	Formula	C₂₅₇H₃₈₃N₆₅O₇₇S₆	Storage (From the date of receipt)	3 years -20°C powder
CAS No.	11061-68-0	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Read more about storage stability stock solution CAS number

Mechanism of Action

In vitro	Insulin (human), an inducer of AKT phosphorylation, reduces the levels of LC3-II, VP1 by the AKT-AMPKMAPK-MTOR pathway in SVV-infected cells.
References	[1] https://pubmed.ncbi.nlm.nih.gov/26537234/ [2] https://pubmed.ncbi.nlm.nih.gov/34757844/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-01-06)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07321028	ENROLLING_BY_INVITATION	Cellular Injury and Post-Cryogenic Recovery; Cryogenic Cellular Stress; Cold-Induced Cellular Injury; Thermal Injury Response; Post-Thaw Viability Impairment; Osmotic Stress Injury; Biomechanical Injury Modeling (In-Vitro); Blunt Force Injuries to the Extremities (Cellular Injury Model); Tissue Damage and Recovery Pathways; Hypothermic Tissue Stress; Cellular Regeneration and Repair	Truway Health, Inc.	2025-12-10	EARLY_PHASE1
NCT04062890	WITHDRAWN	Hyperinsulinism; Insulin Resistance; Insulin Sensitivity; Glucose Intolerance; Hypertension	University of Arizona	2030-04-15	PHASE2
NCT00117936	NOT_YET_RECRUITING	Coronary Disease; Coronary Heart Disease; Myocardial Ischemia; Coronary Arteriosclerosis	Venturis Therapeutics, Inc.	2027-09-01	PHASE2
NCT07593859	RECRUITING	Healthy Adult Participants	Northeastern University	2026-02-01
NCT07403604	RECRUITING	Hyperinsulinemia; Insulin Resistance; Non-Alcoholic Fatty Liver Disease; Prediabetic State; Obesity	Columbia University	2026-07-01	PHASE1
NCT07659028	NOT_YET_RECRUITING	Prediabetes; Obesity & Overweight; Inflamation; Oxidative Stress	National and Kapodistrian University of Athens	2026-07-01

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