CAS No. 352-97-6
Batch:
Purity:98.5
Chemical Structure
Check the
Guanidinoacetic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(diaminomethylideneamino)acetic acid | |
|---|---|---|
| CAS Number | 352-97-6 | |
| Molecular Formula |
C3H7N3O2 |
|
| Molecular Weight (MW) | 117.11 | |
| InChIKey | BPMFZUMJYQTVII-UHFFFAOYSA-N |
Guanidinoacetic acid is a natural endogenous metabolite and the immediate biosynthetic precursor of creatine. It is synthesized from L-arginine and glycine by L-arginine:glycine amidinotransferase and subsequently methylated by guanidinoacetate N-methyltransferase to form creatine. Through replenishing intracellular creatine stores and supporting high-energy phosphate transfer in the phosphocreatine system, guanidinoacetic acid plays an essential role in cellular energy homeostasis and cellular bioenergetics.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 4-Methylpyridine | 5 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.