GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 M1nUU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmL5TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG1PFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC56NEe3JO69VQ>? NF;HV2dUSU6JRWK=
NCI-H1694 MkfuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[5OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njh5NEmg{txO M4LtRnNCVkeHUh?=
NCI-H1963 M4jWeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3\BSmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixPVY{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5{N{izPUDPxE1? MlPSV2FPT0WU
NCI-H2081 MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4iwS2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwNkC0OEDPxE1? NFTyelRUSU6JRWK=
NCI-H209 NXLZdJk3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV3Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvPjJ5MjFOwG0> NXrkdYNoW0GQR1XS
NCI-H2107 NYHMRodJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHz1cpRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlExPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ3Lk[1OlEh|ryP NWHDbmV4W0GQR1XS
NCI-H2126 M3\HdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NViwOFFyUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkWwOFI3KM7:TR?= NVHxWlNZW0GQR1XS
NCI-H2171 NWG2O|FQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWXYc4VEUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm1PVM4KM7:TR?= Mn3IV2FPT0WU
NCI-H2227 NFK2WXJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkKyO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvQDh4MU[g{txO M4OyfHNCVkeHUh?=
NCI-H524 NFXoOFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{DuUmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NlQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56N{[zJO69VQ>? MmLkV2FPT0WU
NCI-H526 NEDMWIlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHzEe|lKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUSzNUDPxE1? MVnTRW5ITVJ?
NCI-H720 M4nZbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mni1TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEeyNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDVzNkGg{txO NVnkeJBIW0GQR1XS
NMC-G1 MoC0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkX6TY5pcWKrdHnvckBw\iCqdX3hckBPVUNvR{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOU4xPTd6IN88US=> NFXWRXpUSU6JRWK=
NOS-1 cell NYj2WXloT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGjwT5BKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU45OjJ7NDFOwG0> NHfQOGRUSU6JRWK=
OCI-AML2 cell Mmj6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1\rd2lvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC57NEm2JO69VQ>? NVu4[opvW0GQR1XS
OCUB-M cell NEHBTG1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M33TUWlvcGmkaYTpc44hd2ZiaIXtZY4hV0OXQj3NJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOjBzIN88US=> MXjTRW5ITVJ?
ONS-76 cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2T2TGlvcGmkaYTpc44hd2ZiaIXtZY4hV06VLUe2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTF7MTFOwG0> NVvqelU2W0GQR1XS
OS-RC-2 cell NWjkOoFxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGTDZXNKdmirYnn0bY9vKG:oIHj1cYFvKE:VLWLDMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi5zOUWg{txO MX\TRW5ITVJ?
OVCAR-4 cell NHrkdFlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH25d2tKdmirYnn0bY9vKG:oIHj1cYFvKE:YQ1HSMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdzOEC4JO69VQ>? M4PJNXNCVkeHUh?=
P30-OHK cell NUKxOZU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{fFWGlvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjJ6N{eg{txO M17pSnNCVkeHUh?=
P30-OHK cell M2jC[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIjVOXZKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvODR7NUSg{txO M1HjeXNCVkeHUh?=
PSN1 cell NXHHUpJ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2TNZ2lvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNlIyOjZizszN M2\X[nNCVkeHUh?=
QIMR-WIL cell NUm2XIU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn6wTY5pcWKrdHnvckBw\iCqdX3hckBSUU2ULWfJUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPDlyMESg{txO MVHTRW5ITVJ?
RCC10RGB cell NVzLS|V3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJHJESzFyUlfCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvQTB|NjFOwG0> M4GwbnNCVkeHUh?=
RKO cell M4XmOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn21TY5pcWKrdHnvckBw\iCqdX3hckBTU09iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OlYzKM7:TR?= NHv0W4JUSU6JRWK=
RL95-2 cell NGHySphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXnJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlY4KM7:TR?= NH3KW3dUSU6JRWK=
RPMI-6666 cell NEjYVW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmrrTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLU[2OlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC53MkO2JO69VQ>? MmW2V2FPT0WU
RPMI-8402 cell M1LkN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVzkXZF{UW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg1ODJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkW4OVYh|ryP MWXTRW5ITVJ?
RXF393 cell NE\XOZdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXLQdplqUW6qaXLpeIlwdiCxZjDoeY1idiCUWF[zPVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN7MzFOwG0> NIjTcWtUSU6JRWK=
Ramos-2G6-4C10 cell M2fFc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4K5NWlvcGmkaYTpc44hd2ZiaIXtZY4hWmGvb4OtNmc3NTSFMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlM2PyEQvF2= MVrTRW5ITVJ?
SCLC-21H cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUXxU4JxUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1zDMVIyUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwNkGxOFkh|ryP NXPj[4RvW0GQR1XS
SF126 cell NF[0dW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NITXVm5KdmirYnn0bY9vKG:oIHj1cYFvKFOIMUK2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvQDN{Md88US=> NUDtVpNEW0GQR1XS
SF268 cell NFfpVGhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIDqdWJKdmirYnn0bY9vKG:oIHj1cYFvKFOIMk[4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok4zOzF6MzFOwG0> NU\QWI04W0GQR1XS
SF539 cell NEXwS3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUXJcohq[mm2aX;uJI9nKGi3bXHuJHNHPTN7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yPFY3OSEQvF2= NVfPRWhmW0GQR1XS
SH-4 cell MofRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUjJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= NV\K[Y5{W0GQR1XS
SIG-M5 cell NF;GcoFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7Kd|RKdmirYnn0bY9vKG:oIHj1cYFvKFOLRz3NOUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjd{NUmg{txO NV[zXWFYW0GQR1XS
SJSA-1 cell NV\ue2RDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUfjT3F2UW6qaXLpeIlwdiCxZjDoeY1idiCVSmPBMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB2NUK2JO69VQ>? NYq2WlNoW0GQR1XS
SK-LMS-1 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH3NcWtKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzNV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwNUm2OUDPxE1? NEXBOFJUSU6JRWK=
SK-MM-2 cell MnSxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MorFTY5pcWKrdHnvckBw\iCqdX3hckBUUy2PTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFIvOzRyNTFOwG0> M{TBUnNCVkeHUh?=
SK-N-DZ cell NFvQb29Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vRGqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlQ5OzF2IN88US=> NULXfWU{W0GQR1XS
SK-NEP-1 cell MofKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUfJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPTR3NjFOwG0> NHHtWZNUSU6JRWK=
SK-PN-DW cell NVj4[GVOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3W1fGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPC57N{O2JO69VQ>? MnjEV2FPT0WU
SNB75 cell MkLxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmfpTY5pcWKrdHnvckBw\iCqdX3hckBUVkJ5NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuNFc4OzdizszN MnH2V2FPT0WU
SR cell NWHYfGhLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4\abmlvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwNFE{PyEQvF2= MX\TRW5ITVJ?
SU-DHL-1 cell MlOwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEjnTIRKdmirYnn0bY9vKG:oIHj1cYFvKFOXLVTIUE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwN{OzOkDPxE1? NYTjS5pPW0GQR1XS
SW684 cell NEfhXGxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{DucWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d4OESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU4xOTFizszN MU\TRW5ITVJ?
SW872 cell NGPJd5RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2\XRmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg5PjV4IN88US=> MYHTRW5ITVJ?
SW962 cell NHeycndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml;4TY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlc2OjFizszN M3HXenNCVkeHUh?=
697 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEj1RYdKdmirYnn0bY9vKG:oIHj1cYFvKDZ7NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlk6OSEQvF2= MYDTRW5ITVJ?
8-MG-BA cell M3;XOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3;hS2lvcGmkaYTpc44hd2ZiaIXtZY4hQC2PRz3CRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjB5OUOg{txO MlHwV2FPT0WU
A101D cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJGEyODGGIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64O|A{PCEQvF2= MmPLV2FPT0WU
ACN cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEPrXYtKdmirYnn0bY9vKG:oIHj1cYFvKEGFTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKxMlQ{QDdizszN M4\UUXNCVkeHUh?=
AM-38 cell MlHnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWTQSZFnUW6qaXLpeIlwdiCxZjDoeY1idiCDTT2zPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOjZ|Mkeg{txO Ml70V2FPT0WU
ATN-1 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVjBW|VkUW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd3NUWg{txO NH7GbVNUSU6JRWK=
BB30-HNC cell M3fDcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXToR3dGUW6qaXLpeIlwdiCxZjDoeY1idiCEQkOwMWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{LkK1N|Ih|ryP NG\nN5pUSU6JRWK=
BB49-HNC cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUnJcohq[mm2aX;uJI9nKGi3bXHuJGJDPDlvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODd6OTFOwG0> NUXPd2RIW0GQR1XS
human BC-1 cell M3PRNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVuyOlQ2UW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46PzFyNzFOwG0> M3n3fnNCVkeHUh?=
BE-13 cell MnHMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFHXeIVKdmirYnn0bY9vKG:oIHj1cYFvKEKHLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDB6Md88US=> M4TONnNCVkeHUh?=
BL-70 cell MmLwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PBS2lvcGmkaYTpc44hd2ZiaIXtZY4hSkxvN{CgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlQxPzB|IN88US=> MUTTRW5ITVJ?
BV-173 cell NW\iZ5FGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mnq5TY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE45QDV7IN88US=> NX\pR5ZkW0GQR1XS
Becker cell NHuybmJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlzWTY5pcWKrdHnvckBw\iCqdX3hckBD\WOtZYKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46PTR3IN88US=> M1W1XnNCVkeHUh?=
CAL-148 cell Mm[zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33Ob2lvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO NWmxPYJSW0GQR1XS
TE-10 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWm1[VN4UW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh2MkOg{txO M1ezVnNCVkeHUh?=
TE-12 cell MlvrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M32xSWlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk41OTF2IN88US=> M{XpO3NCVkeHUh?=
TE-8 cell M2joSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MljjTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOlA5QSEQvF2= MYrTRW5ITVJ?
TE-9 cell M{K3bmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV24UY1tUW6qaXLpeIlwdiCxZjDoeY1idiCWRT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPjN6MTFOwG0> NWTEUGl4W0GQR1XS
TGW cell NYCyVWE{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2TzPWlvcGmkaYTpc44hd2ZiaIXtZY4hXEeZIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuN|U4PyEQvF2= NEfsWXhUSU6JRWK=
UACC-257 cell NVviNFRvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3u1OGlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdyNkK1JO69VQ>? MnjBV2FPT0WU
WSU-NHL cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkPoTY5pcWKrdHnvckBw\iCqdX3hckBYW1VvTljMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlcvOTlyNzFOwG0> MmHpV2FPT0WU
no-10 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXW3NFhlUW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjZ6NE[g{txO MorIV2FPT0WU
no-11 cell NGezNFdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuNFI3OyEQvF2= MUXTRW5ITVJ?
CAS-1 cell NIDw[phIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4r1SmlvcGmkaYTpc44hd2ZiaIXtZY4hS0GVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg1PyEQvF2= MlrLV2FPT0WU
CCRF-CEM cell NGqwS4tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYjPepRbUW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwNkWzPVIh|ryP NEK1XXhUSU6JRWK=
CMK cell M{DZdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LMZmlvcGmkaYTpc44hd2ZiaIXtZY4hS02NIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wNVMzOyEQvF2= NEW4WIdUSU6JRWK=
COLO-829 cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnLhTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLUiyPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOjR{Mk[g{txO MnvKV2FPT0WU
COR-L279 cell M33remdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnvETY5pcWKrdHnvckBw\iCqdX3hckBEV1JvTEK3PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvODd|ODFOwG0> MWXTRW5ITVJ?
CP66-MEL cell M1f6RWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NG\nTXBKdmirYnn0bY9vKG:oIHj1cYFvKEOSNk[tUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzZwNUS5O{DPxE1? NWPpU255W0GQR1XS
CRO-AP2 cell M4nWU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGHB[mZKdmirYnn0bY9vKG:oIHj1cYFvKEOUTz3BVFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjN4MEi4JO69VQ>? M{LNNXNCVkeHUh?=
CTV-1 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGCxZlFKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvQTF2NTFOwG0> NH[5WWhUSU6JRWK=
Calu-6 cell NGriWJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYTzc3VTUW6qaXLpeIlwdiCxZjDoeY1idiCFYXz1MVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Py53OE[g{txO MWPTRW5ITVJ?
D-247MG cell M1TIPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYDJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjR5TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlYzQDF2IN88US=> NED1TnNUSU6JRWK=
D-263MG cell M{TNVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFHCfmRKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB6NUC5JO69VQ>? M2fmWHNCVkeHUh?=
D-336MG cell M{X1cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlK5TY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Ojh3NDFOwG0> Mo[2V2FPT0WU
D-392MG cell M{j6[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml3oTY5pcWKrdHnvckBw\iCqdX3hckBFNTN7Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41OzB|OTFOwG0> MXPTRW5ITVJ?
D-502MG cell M4H2b2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUXPblJSUW6qaXLpeIlwdiCxZjDoeY1idiCGLUWwNm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC53M{S5NkDPxE1? M120enNCVkeHUh?=
D-542MG cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkTwTY5pcWKrdHnvckBw\iCqdX3hckBFNTV2Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOzF3MjFOwG0> MYTTRW5ITVJ?
DB cell NFX1XIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmPYTY5pcWKrdHnvckBw\iCqdX3hckBFSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR5LkG0NVch|ryP NGDReY9USU6JRWK=
DEL cell M2r0[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmHHTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= NHniRYxUSU6JRWK=
DMS-114 cell NIW4NGdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnrhTY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUG0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvQDR4ODFOwG0> NF\nfYRUSU6JRWK=
DMS-153 cell NGGzXXNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkX6TY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUWzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFIvQTl{MzFOwG0> M1y5XXNCVkeHUh?=
DOHH-2 cell M2nlOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlTJTY5pcWKrdHnvckBw\iCqdX3hckBFV0iKLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlIzPzZ2IN88US=> MoezV2FPT0WU
DSH1 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUTyWGh{UW6qaXLpeIlwdiCxZjDoeY1idiCGU1ixJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE41OzZ{MzFOwG0> MkDnV2FPT0WU
Daudi cell NVT3VFhGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFi0fHNKdmirYnn0bY9vKG:oIHj1cYFvKESjdXTpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4xQThyMjFOwG0> NH7MWlBUSU6JRWK=
EC-GI-10 cell NU[5WVVkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVPJcohq[mm2aX;uJI9nKGi3bXHuJGVENUeLLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFQvOjV6OTFOwG0> M2rXV3NCVkeHUh?=
ECC4 cell M4nISWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnzDTY5pcWKrdHnvckBw\iCqdX3hckBGS0N2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{KuNVg6PiEQvF2= NXWwXpBWW0GQR1XS
EM-2 cell NULKVJVuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFrPWWxKdmirYnn0bY9vKG:oIHj1cYFvKEWPLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlQ2PTl2IN88US=> NF\DVnlUSU6JRWK=
ES1 cell M2j5[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEDib4lKdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN NFrwfIxUSU6JRWK=
ES3 cell NGPq[5RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{XxNmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuOFczQSEQvF2= MnzZV2FPT0WU
ES4 cell NX;STnZST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH2wZY1KdmirYnn0bY9vKG:oIHj1cYFvKEWVNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO1MlE6PSEQvF2= MWfTRW5ITVJ?
ES6 cell MmnKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIji[JJKdmirYnn0bY9vKG:oIHj1cYFvKEWVNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlQ4OzNizszN MWLTRW5ITVJ?
ES7 cell MlrzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3\GNGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT6yN|EzPCEQvF2= M1;2enNCVkeHUh?=
ES8 cell NFT0VnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF;ofFVKdmirYnn0bY9vKG:oIHj1cYFvKEWVODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFE6OjRizszN MlG3V2FPT0WU
EW-18 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmG0TY5pcWKrdHnvckBw\iCqdX3hckBGXy1zODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlY4PTlizszN M3[1VXNCVkeHUh?=
EW-22 cell NUTGZnNOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\HN4tLUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2yNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4Njd7NEeg{txO MlLKV2FPT0WU
GCIY cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3;qemlvcGmkaYTpc44hd2ZiaIXtZY4hT0OLWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUmuPFA{QDlizszN NW\NV5ZUW0GQR1XS
GDM-1 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYDJcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= NH;YSHRUSU6JRWK=
GI-1 cell NVLNdWM{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{H2bWlvcGmkaYTpc44hd2ZiaIXtZY4hT0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA2OjNizszN MYjTRW5ITVJ?
GI-ME-N cell NFrleZZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGdKNU2HLV6gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1QTVzIN88US=> MXnTRW5ITVJ?
GR-ST cell M2faPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXOxUmRSUW6qaXLpeIlwdiCxZjDoeY1idiCJUj3TWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njd7MEKg{txO M3PxU3NCVkeHUh?=
GT3TKB cell MlP6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mni5TY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlYxOzh7IN88US=> M3fNN3NCVkeHUh?=
HAL-01 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFzvOHNKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPjl5MUKg{txO NVHIO5VjW0GQR1XS
HCC1599 cell NH3yNVZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHPkU4ZKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py54MEGxJO69VQ>? Mn;wV2FPT0WU
HCC2218 cell Moq1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1z4dWlvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkKxPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjN6M{Sg{txO NWfJW3Z{W0GQR1XS
HD-MY-Z cell MkTLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYLWSZV4UW6qaXLpeIlwdiCxZjDoeY1idiCKRD3NXU1bKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwMkG0OkDPxE1? MnjyV2FPT0WU
HL-60 cell NE\KbHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIDYN4ZKdmirYnn0bY9vKG:oIHj1cYFvKEiOLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOjFzNDFOwG0> NGnPVGdUSU6JRWK=
HOP-62 cell NXTRV4xVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmLpTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PTJ5IN88US=> MnPSV2FPT0WU
HT cell NVHRdVQ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYnQTGcxUW6qaXLpeIlwdiCxZjDoeY1idiCKVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuOFQ{OjFizszN MYjTRW5ITVJ?
HT-144 cell NGPNSWRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXSyfXY3UW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjlyNki2JO69VQ>? NIPWOW5USU6JRWK=
HUTU-80 cell M3v0fWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MknQTY5pcWKrdHnvckBw\iCqdX3hckBJXVSXLUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{44QDl6NjFOwG0> MnSzV2FPT0WU
IST-MEL1 cell M1;qbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1HSSmlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi57MEi2JO69VQ>? MWTTRW5ITVJ?
IST-SL1 cell NHPidHBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWDJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlE4ODd7IN88US=> NWrKN3lIW0GQR1XS
IST-SL2 cell NF3pO4RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlG1TY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> MUjTRW5ITVJ?
K052 cell Mk\GS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIr6[ZVKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> NFHJZolUSU6JRWK=
K5 cell NXHpRW1mT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlPuTY5pcWKrdHnvckBw\iCqdX3hckBMPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN|LkW5NVUh|ryP NGTOXolUSU6JRWK=
KALS-1 cell NEnCeW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1jR[GlvcGmkaYTpc44hd2ZiaIXtZY4hU0GOUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvOzl4OTFOwG0> NU\0[5dtW0GQR1XS
KARPAS-422 cell MmLiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1v1bmlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP NIXCXJpUSU6JRWK=
KARPAS-45 cell NX;FSpBkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFrHVnFKdmirYnn0bY9vKG:oIHj1cYFvKEuDUmDBV{01PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwMUGyOFch|ryP NHXm[IJUSU6JRWK=
KE-37 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWPvWHJzUW6qaXLpeIlwdiCxZjDoeY1idiCNRT2zO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvQDN3IN88US=> Mlf4V2FPT0WU
KG-1 cell NXjh[4xpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFXweHpKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PzV5IN88US=> MUXTRW5ITVJ?
KGN cell NFjRW5BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUnpVmZpUW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PzR{IN88US=> MljzV2FPT0WU
KM12 cell M{nmNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlLjTY5pcWKrdHnvckBw\iCqdX3hckBMVTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61Nlk3PCEQvF2= MlnZV2FPT0WU
KMOE-2 cell M{H5bWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkewTY5pcWKrdHnvckBw\iCqdX3hckBMVU:HLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE41PTR7IN88US=> M2\1PXNCVkeHUh?=
KNS-42 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mom5TY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlgyQTF3IN88US=> MXnTRW5ITVJ?
KNS-81-FD cell Mle1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYT5SI4zUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtPFEuTkRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nz60NlYh|ryP M1jmc3NCVkeHUh?=
KS-1 cell NVXVUIk3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{jINmlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA1PiEQvF2= MmDEV2FPT0WU
KU812 cell NGK1bZVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGtWQDF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuOFg1KM7:TR?= M1eyeXNCVkeHUh?=
L-540 cell M1TFcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIm3S3VKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR2NTFOwG0> Mmn4V2FPT0WU
LAMA-84 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn72TY5pcWKrdHnvckBw\iCqdX3hckBNSU2DLUi0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPjd2MjFOwG0> NHTCcpJUSU6JRWK=
LB1047-RCC cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGxDOTB2Nz3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQC5|OEizJO69VQ>? MlnFV2FPT0WU
LB2241-RCC cell M1HUWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkDSTY5pcWKrdHnvckBw\iCqdX3hckBNSjJ{NEGtVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTBwNUWzOkDPxE1? MmHuV2FPT0WU
LB2518-MEL cell NGTwW2tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4K5[mlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwN{G0PVbPxE1? MVHTRW5ITVJ?
LB831-BLC cell M3LnR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2C2S2lvcGmkaYTpc44hd2ZiaIXtZY4hVEJ6M{GtRmxEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTFwMUeyOkDPxE1? NVfPZXZIW0GQR1XS
LB996-RCC cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NETxR2hKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lke0N|Eh|ryP NGGwfY1USU6JRWK=
LC4-1 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYTwd|RuUW6qaXLpeIlwdiCxZjDoeY1idiCOQ{StNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMzNjh|NEGg{txO M{S3UnNCVkeHUh?=
LOUCY cell NHKxTY5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mnz2TY5pcWKrdHnvckBw\iCqdX3hckBNV1WFWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVUzPzZizszN NUW3TXQyW0GQR1XS
LOXIMVI cell NGXjSYJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmP1TY5pcWKrdHnvckBw\iCqdX3hckBNV1iLTW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvOjF{MjFOwG0> M17CWHNCVkeHUh?=
LS-123 cell M4LzV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlS3TY5pcWKrdHnvckBw\iCqdX3hckBNWy1zMkOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU4zOjV6IN88US=> Ml3UV2FPT0WU
LU-134-A cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3LVWmlvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO0MWEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjF2ME[4JO69VQ>? Mo\JV2FPT0WU
LU-139 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4POe2lvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOjF6IN88US=> M2D4WXNCVkeHUh?=
LXF-289 cell M{LpdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1[4bGlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjR|NUJOwG0> NV30dWZVW0GQR1XS
MC116 cell MnLoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGXl[ZVKdmirYnn0bY9vKG:oIHj1cYFvKE2FMUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFUvODh2MTFOwG0> NFPJNY1USU6JRWK=
MDA-MB-134-VI cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFG4NVlKdmirYnn0bY9vKG:oIHj1cYFvKE2GQT3NRk0yOzRvVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU4zPDh4IN88US=> M{Pjd3NCVkeHUh?=
MFH-ino cell M{G4Smdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjpemZHUW6qaXLpeIlwdiCxZjDoeY1idiCPRlitbY5wKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54NEO4N{DPxE1? NXS2VpdwW0GQR1XS
MHH-NB-11 cell NYTCU3oyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODZ4OTFOwG0> M2\mNHNCVkeHUh?=
ML-2 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGjZe4ZKdmirYnn0bY9vKG:oIHj1cYFvKE2OLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlQxOzB2IN88US=> MneyV2FPT0WU
MOLT-13 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn\GTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE41OzZ3MzFOwG0> NHXTfFNUSU6JRWK=
MOLT-16 cell NF;RNWlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYLYdYhsUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5zMUG2N{DPxE1? NUjUOVFLW0GQR1XS
MOLT-4 cell NWW4d5U6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI\EW3pKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjRzMkSg{txO NUH6[4hEW0GQR1XS
MPP-89 cell NUHuN2Q3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWjZc3d4UW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ3OUKyJO69VQ>? M33i[3NCVkeHUh?=
MRK-nu-1 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVK3e3hrUW6qaXLpeIlwdiCxZjDoeY1idiCPUlutcpUuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNUe1O|Ih|ryP MkfVV2FPT0WU
MSTO-211H cell NHzOSW1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUnDbIxTUW6qaXLpeIlwdiCxZjDoeY1idiCPU2TPMVIyOUhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj64Olkh|ryP MlLFV2FPT0WU
MV-4-11 cell MmnUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlnHTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yOzlzNTFOwG0> MVTTRW5ITVJ?
NALM-6 cell Mn:wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoewTY5pcWKrdHnvckBw\iCqdX3hckBPSUyPLU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlU3OTB7IN88US=> Mkn5V2FPT0WU
NB1 cell NGTPUVhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFnvSYdKdmirYnn0bY9vKG:oIHj1cYFvKE6EMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPFQ{PjlizszN M4L0OnNCVkeHUh?=
NB10 cell NWXpfXhzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1nLc2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVM6OTVizszN MnfiV2FPT0WU
NB12 cell MnTkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3LRSmlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG2MlU3PTZizszN NUTwRnh5W0GQR1XS
NB13 cell M4LmcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIXhPXpKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlMyOjd6IN88US=> M3jaRnNCVkeHUh?=
NB17 cell M1jmXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHH0WVRKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlU5ODVzIN88US=> NXy4fINOW0GQR1XS
NB6 cell M1H2S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUDJcohq[mm2aX;uJI9nKGi3bXHuJG5DPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNUmxNVQh|ryP MXTTRW5ITVJ?
NCCIT cell M13KO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2fMd2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOFSWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU45PDV|IN88US=> M4PMTnNCVkeHUh?=
NCI-H1155 cell M4izcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUG1OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjN2MEig{txO M1vwRnNCVkeHUh?=
NCI-H1304 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVzx[FJbUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{ODRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT64PVgzKM7:TR?= NFm2V3lUSU6JRWK=
NCI-H1355 cell M3nLdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXfJNJlUUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{PTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Lkm0NVEh|ryP NULQfWljW0GQR1XS
NCI-H1395 cell NIrHdFFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoiyTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56N{m1JO69VQ>? M2XYXXNCVkeHUh?=
NCI-H1417 cell NEWx[2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSxO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjd3MkKg{txO MlrOV2FPT0WU
NCI-H1436 cell NH7RTW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnXwTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG0N|Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njh2MUCxJO69VQ>? MUDTRW5ITVJ?
NTERA-S-cl-D1 cell NEnXU5FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVfJcohq[mm2aX;uJI9nKGi3bXHuJG5VTVKDLWOtZ4wuTDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj64PVM2KM7:TR?= MlLCV2FPT0WU
JiyoyeP-2003 cell M1L6TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXixTWE6UW6qaXLpeIlwdiCxZjDoeY1idiCMaYnvfYVRNTJyMEOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43Ojh2IN88US=> M2Xp[XNCVkeHUh?=

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In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
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  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID