GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 MlrFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1fnS2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOVgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOES3O{DPxE1? MWfTRW5ITVJ?
NCI-H1694 NIXFUW9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MULJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[5OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njh5NEmg{txO MYLTRW5ITVJ?
NCI-H1963 MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlHmTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG5OlMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ5OEO5JO69VQ>? MV3TRW5ITVJ?
NCI-H2081 MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4Hrc2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwNkC0OEDPxE1? MYHTRW5ITVJ?
NCI-H209 MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvVTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjZ{N{Kg{txO MVXTRW5ITVJ?
NCI-H2107 NHrFbFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGwO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI2NjZ3NkGg{txO MmDYV2FPT0WU
NCI-H2126 NEPibY9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2rlXmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi53MESyOkDPxE1? MlL0V2FPT0WU
NCI-H2171 NGfLfYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXXJUHU1UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm1PVM4KM7:TR?= MoXQV2FPT0WU
NCI-H2227 NY\HOZdYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1jvU2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNlI4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py56OE[xOkDPxE1? M{DH[3NCVkeHUh?=
NCI-H524 NUfqc5dUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1zsR2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NlQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56N{[zJO69VQ>? Mo\1V2FPT0WU
NCI-H526 MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnXPTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV2M{Gg{txO NGK1dlFUSU6JRWK=
NCI-H720 MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{KwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk41PTF4MTFOwG0> M1SwO3NCVkeHUh?=
NMC-G1 M1TvNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUCxfJVWUW6qaXLpeIlwdiCxZjDoeY1idiCQTVOtS|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS5yNUe4JO69VQ>? M4\MdHNCVkeHUh?=
NOS-1 cell NXf6NYw4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGrXOYlKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU45OjJ7NDFOwG0> M1vJW3NCVkeHUh?=
OCI-AML2 cell M3qzNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnzyTY5pcWKrdHnvckBw\iCqdX3hckBQS0lvQV3MNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjl2OU[g{txO NWP5ZlBZW0GQR1XS
OCUB-M cell NYf4dnpsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWXJcohq[mm2aX;uJI9nKGi3bXHuJG9EXUJvTTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG3MlIxOSEQvF2= M1XwUnNCVkeHUh?=
ONS-76 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlrBTY5pcWKrdHnvckBw\iCqdX3hckBQVlNvN{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46OTlzIN88US=> M1fweXNCVkeHUh?=
OS-RC-2 cell M3T4bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFPCbnpKdmirYnn0bY9vKG:oIHj1cYFvKE:VLWLDMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Pi5zOUWg{txO Mn;UV2FPT0WU
OVCAR-4 cell Ml3KS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NImzSY9KdmirYnn0bY9vKG:oIHj1cYFvKE:YQ1HSMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdzOEC4JO69VQ>? MVfTRW5ITVJ?
P30-OHK cell NHrLOI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{XEUmlvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjJ6N{eg{txO NFHQcWRUSU6JRWK=
P30-OHK cell MlLSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2jjc2lvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4xPDl3NDFOwG0> Mlq2V2FPT0WU
PSN1 cell MnPQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVHJcohq[mm2aX;uJI9nKGi3bXHuJHBUVjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkKyNVI3KM7:TR?= M1nOdHNCVkeHUh?=
QIMR-WIL cell NWHnc5dST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXfGNY5LUW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEmwNFQh|ryP MV7TRW5ITVJ?
RCC10RGB cell NH3xSJNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV7hNYR4UW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF6LkmwN|Yh|ryP MlPiV2FPT0WU
RKO cell Mn;YS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3TBdmlvcGmkaYTpc44hd2ZiaIXtZY4hWkuRIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUCuOVY3OiEQvF2= Mk\RV2FPT0WU
RL95-2 cell NE\KPGRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4Pv[2lvcGmkaYTpc44hd2ZiaIXtZY4hWkx7NT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVAvPjdizszN MoXVV2FPT0WU
RPMI-6666 cell NVTicmJST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnzVTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLU[2OlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC53MkO2JO69VQ>? NEC3PHlUSU6JRWK=
RPMI-8402 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVvrXYc5UW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg1ODJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkW4OVYh|ryP M1HL[nNCVkeHUh?=
RXF393 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWToXnY2UW6qaXLpeIlwdiCxZjDoeY1idiCUWF[zPVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN7MzFOwG0> NUD3bXc{W0GQR1XS
Ramos-2G6-4C10 cell MoLTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYS1bVA3UW6qaXLpeIlwdiCxZjDoeY1idiCUYX3vd{0zTzZvNFOxNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzV5IN88US=> Ml7qV2FPT0WU
SCLC-21H cell NIq2coVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHfZe5RKdmirYnn0bY9vKG:oIHj1cYFvKFOFTFOtNlFJKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py54MUG0PUDPxE1? NHjSXVVUSU6JRWK=
SF126 cell MknZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXjJcohq[mm2aX;uJI9nKGi3bXHuJHNHOTJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuPFMzOc7:TR?= NWfwNWJtW0GQR1XS
SF268 cell M3zzdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnPyTY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNlMyQDNizszN M3n1T3NCVkeHUh?=
SF539 cell M2jOcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWLJcohq[mm2aX;uJI9nKGi3bXHuJHNHPTN7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yPFY3OSEQvF2= MUTTRW5ITVJ?
SH-4 cell NULCd2VjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXrJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= NFLwenBUSU6JRWK=
SIG-M5 cell MmrZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1fNU2lvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvPzJ3OTFOwG0> M{fHbnNCVkeHUh?=
SJSA-1 cell MoLyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGrHcnVKdmirYnn0bY9vKG:oIHj1cYFvKFOMU1GtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvODR3Mk[g{txO M321d3NCVkeHUh?=
SK-LMS-1 cell NH\QfotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4jPe2lvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi53OU[1JO69VQ>? M3fTVnNCVkeHUh?=
SK-MM-2 cell M2\j[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYnJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2PLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk4{PDB3IN88US=> NIPaR5JUSU6JRWK=
SK-N-DZ cell M2TiUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vRGqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlQ5OzF2IN88US=> NEXhZZRUSU6JRWK=
SK-NEP-1 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWrJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPTR3NjFOwG0> NXX2[HptW0GQR1XS
SK-PN-DW cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWjyUIt4UW6qaXLpeIlwdiCxZjDoeY1idiCVSz3QUk1FXyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lkm3N|Yh|ryP MV;TRW5ITVJ?
SNB75 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIfJR2lKdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE4xPzd|NzFOwG0> MY\TRW5ITVJ?
SR cell MofzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWTJcohq[mm2aX;uJI9nKGi3bXHuJHNTKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMECxN|ch|ryP M3OxfXNCVkeHUh?=
SU-DHL-1 cell Mk\TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXLpSVdbUW6qaXLpeIlwdiCxZjDoeY1idiCVVT3ETGwuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{LkezN|Yh|ryP NYfNRpJ6W0GQR1XS
SW684 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlyyTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= M4PmN3NCVkeHUh?=
SW872 cell NGPCbphIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmDRTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFg3PTZizszN NX;JOW15W0GQR1XS
SW962 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWDJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTZ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuO|UzOSEQvF2= M2ixV3NCVkeHUh?=
697 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2O3OWlvcGmkaYTpc44hd2ZiaIXtZY4hPjl5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yPVkyKM7:TR?= NYDUVlZbW0GQR1XS
8-MG-BA cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXTJcohq[mm2aX;uJI9nKGi3bXHuJFguVUdvQlGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4xPzl|IN88US=> MlrXV2FPT0WU
A101D cell NVrzcpF2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFPkcZdKdmirYnn0bY9vKG:oIHj1cYFvKEFzMEHEJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45PzB|NDFOwG0> NY\YZ4dHW0GQR1XS
ACN cell NV;XSopkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlraTY5pcWKrdHnvckBw\iCqdX3hckBCS05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{MT60N|g4KM7:TR?= MWnTRW5ITVJ?
AM-38 cell NWPScFhOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYjJcohq[mm2aX;uJI9nKGi3bXHuJGFONTN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz6yOlMzPyEQvF2= MlXDV2FPT0WU
ATN-1 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1PTNmlvcGmkaYTpc44hd2ZiaIXtZY4hSVSQLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOE44PTV3IN88US=> M3;EU3NCVkeHUh?=
BB30-HNC cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYjJcohq[mm2aX;uJI9nKGi3bXHuJGJDOzBvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOjV|MjFOwG0> NHP5SIFUSU6JRWK=
BB49-HNC cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWXJcohq[mm2aX;uJI9nKGi3bXHuJGJDPDlvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODd6OTFOwG0> MX\TRW5ITVJ?
human BC-1 cell NGS1ZYRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXLJcohq[mm2aX;uJI9nKGi3bXHuJGJENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lkm3NVA4KM7:TR?= MYXTRW5ITVJ?
BE-13 cell NXLxRndIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoW2TY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= MnHWV2FPT0WU
BL-70 cell Mlf1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmrJTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOFA4ODNizszN MXzTRW5ITVJ?
BV-173 cell M2TH[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3zHW2lvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvQDh3OTFOwG0> M2nZRXNCVkeHUh?=
Becker cell NGPLTWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX7TSHVQUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NUS1JO69VQ>? NFfs[VNUSU6JRWK=
CAL-148 cell NITNZpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlP5TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMUS4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|UvPjV3NzFOwG0> NYrYNlcxW0GQR1XS
TE-10 cell MkPGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkKuPFQzOyEQvF2= MmmxV2FPT0WU
TE-12 cell NEXNcYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkTwTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN MX7TRW5ITVJ?
TE-8 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mk\nTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOlA5QSEQvF2= M4[zeHNCVkeHUh?=
TE-9 cell NFLVN4FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M131OGlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO2MlY{QDFizszN M4\NdXNCVkeHUh?=
TGW cell MnX1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmnXTY5pcWKrdHnvckBw\iCqdX3hckBVT1diY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz6zOVc4KM7:TR?= NYmxVoJsW0GQR1XS
UACC-257 cell NHXSNFhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlO4TY5pcWKrdHnvckBw\iCqdX3hckBWSUOFLUK1O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPzB4MkWg{txO M4P2[HNCVkeHUh?=
WSU-NHL cell NVnKNoJYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEDmN4RKdmirYnn0bY9vKG:oIHj1cYFvKFeVVT3OTGwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPy5zOUC3JO69VQ>? MoDBV2FPT0WU
no-10 cell NGPVcJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnLETY5pcWKrdHnvckBw\iCqdX3hckBvdy1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOlY5PDZizszN NUnn[3FDW0GQR1XS
no-11 cell NHfScndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mm\jTY5pcWKrdHnvckBw\iCqdX3hckBvdy1zMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlAzPjNizszN MVnTRW5ITVJ?
CAS-1 cell MmPOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH7kN4ZKdmirYnn0bY9vKG:oIHj1cYFvKEODUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PDdizszN Mn7zV2FPT0WU
CCRF-CEM cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4frRWlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZ3M{myJO69VQ>? NEHmcXNUSU6JRWK=
CMK cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF30W2hKdmirYnn0bY9vKG:oIHj1cYFvKEOPSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFE{OjNizszN MUXTRW5ITVJ?
COLO-829 cell MoHLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPDJ{NjFOwG0> MULTRW5ITVJ?
COR-L279 cell NFLHeYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEHSOG1KdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5yN{O4JO69VQ>? M2D4UnNCVkeHUh?=
CP66-MEL cell NIm2Z3NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{fEPGlvcGmkaYTpc44hd2ZiaIXtZY4hS1B4Nj3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Pi53NEm3JO69VQ>? NVOzVWRuW0GQR1XS
CRO-AP2 cell NUC2S3JQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnHoTY5pcWKrdHnvckBw\iCqdX3hckBEWk9vQWCyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{PjB6ODFOwG0> MmK4V2FPT0WU
CTV-1 cell NV\2ZllRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1m4XmlvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46OTR3IN88US=> M3nNW3NCVkeHUh?=
Calu-6 cell NF7BdWtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkO3TY5pcWKrdHnvckBw\iCqdX3hckBE[Wy3LU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{42QDZizszN NFXVbXFUSU6JRWK=
D-247MG cell NFPpNVRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7aZo9KdmirYnn0bY9vKG:oIHj1cYFvKERvMkS3UWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ{OEG0JO69VQ>? MoHIV2FPT0WU
D-263MG cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\rd|VyUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK2N21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yOEWwPUDPxE1? MUjTRW5ITVJ?
D-336MG cell MmXlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MljmTY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Ojh3NDFOwG0> NIDM[2lUSU6JRWK=
D-392MG cell MmjGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEDDWGNKdmirYnn0bY9vKG:oIHj1cYFvKERvM{myUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjR|MEO5JO69VQ>? MUDTRW5ITVJ?
D-502MG cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIDsXZVKdmirYnn0bY9vKG:oIHj1cYFvKERvNUCyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjV|NEmyJO69VQ>? NF[xd|lUSU6JRWK=
D-542MG cell NULWWFZjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEm0fGhKdmirYnn0bY9vKG:oIHj1cYFvKERvNUSyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi5|MUWyJO69VQ>? MnPWV2FPT0WU
DB cell Ml[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVfJcohq[mm2aX;uJI9nKGi3bXHuJGRDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwMUSxO{DPxE1? NWq3ZVloW0GQR1XS
DEL cell M4fROGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkTXTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= NH\G[29USU6JRWK=
DMS-114 cell M2K3WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWT5eY11UW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? MmDtV2FPT0WU
DMS-153 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm\1TY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUWzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFIvQTl{MzFOwG0> M{i1NHNCVkeHUh?=
DOHH-2 cell NXvEXZZkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDU[VJZUW6qaXLpeIlwdiCxZjDoeY1idiCGT1jIMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjJ{N{[0JO69VQ>? MnrBV2FPT0WU
DSH1 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWHNVnh1UW6qaXLpeIlwdiCxZjDoeY1idiCGU1ixJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE41OzZ{MzFOwG0> NWjveZJsW0GQR1XS
Daudi cell M1zOR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUnJcohq[mm2aX;uJI9nKGi3bXHuJGRifWSrIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6wPVgxOiEQvF2= NXf0UIRCW0GQR1XS
EC-GI-10 cell M3H1ZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXTJcohq[mm2aX;uJI9nKGi3bXHuJGVENUeLLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFQvOjV6OTFOwG0> MV3TRW5ITVJ?
ECC4 cell M4XzfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHf3VlFKdmirYnn0bY9vKG:oIHj1cYFvKEWFQ{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk4yQDl4IN88US=> NV2zS3loW0GQR1XS
EM-2 cell MmO2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYjJcohq[mm2aX;uJI9nKGi3bXHuJGVONTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkS1OVk1KM7:TR?= NYL3cohTW0GQR1XS
ES1 cell M{DpdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGe0dnJKdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN Ml;CV2FPT0WU
ES3 cell MlLmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnfzTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj60O|I6KM7:TR?= Mn3VV2FPT0WU
ES4 cell Mm\JS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4fJcmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVk2KM7:TR?= Ml\0V2FPT0WU
ES6 cell MmfrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWnJcohq[mm2aX;uJI9nKGi3bXHuJGVUPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMkS3N|Mh|ryP NYTCfFI4W0GQR1XS
ES7 cell NHGwWlJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml7XTY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkKzNVI1KM7:TR?= NVzFWVNHW0GQR1XS
ES8 cell MlrvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHv0NnlKdmirYnn0bY9vKG:oIHj1cYFvKEWVODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFE6OjRizszN MkDyV2FPT0WU
EW-18 cell MkXTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1HIPGlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43PzV7IN88US=> NHrNRZRUSU6JRWK=
EW-22 cell NGmxbndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoHsTY5pcWKrdHnvckBw\iCqdX3hckBGXy1{MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3Mlc6PDdizszN MV3TRW5ITVJ?
GCIY cell NWXFW|NxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NITLO3JKdmirYnn0bY9vKG:oIHj1cYFvKEeFSWmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlgxOzh7IN88US=> MnPYV2FPT0WU
GDM-1 cell MmfqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWTJcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= MWfTRW5ITVJ?
GI-1 cell NGS5fmNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGHU[plKdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxPTJ|IN88US=> MmLEV2FPT0WU
GI-ME-N cell M1PDdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVjLc2psUW6qaXLpeIlwdiCxZjDoeY1idiCJST3NSU1PKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNEm1NUDPxE1? NX3SeVhpW0GQR1XS
GR-ST cell NGH2dGlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYK2TFRJUW6qaXLpeIlwdiCxZjDoeY1idiCJUj3TWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njd7MEKg{txO M374enNCVkeHUh?=
GT3TKB cell MnTrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1HwOmlvcGmkaYTpc44hd2ZiaIXtZY4hT1R|VFvCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU43ODN6OTFOwG0> NFzHZ|JUSU6JRWK=
HAL-01 cell MoTES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUjJcohq[mm2aX;uJI9nKGi3bXHuJGhCVC1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uOlk4OTJizszN MmXwV2FPT0WU
HCC1599 cell NIL6NIpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGXWS25KdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py54MEGxJO69VQ>? NW\tcXd5W0GQR1XS
HCC2218 cell NWPEXHRMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1XCT2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkKxPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjN6M{Sg{txO NVjP[Yx[W0GQR1XS
HD-MY-Z cell MnL4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4jaSmlvcGmkaYTpc44hd2ZiaIXtZY4hUERvTWmtXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI2NjJzNE[g{txO MlTaV2FPT0WU
HL-60 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWjJcohq[mm2aX;uJI9nKGi3bXHuJGhNNTZyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuNlEyPCEQvF2= NUnQV3BGW0GQR1XS
HOP-62 cell NGLH[FJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEC5TnlKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{Njl3Mkeg{txO NWC3dVRTW0GQR1XS
HT cell NYPt[2UxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYHIRnRsUW6qaXLpeIlwdiCxZjDoeY1idiCKVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuOFQ{OjFizszN MVLTRW5ITVJ?
HT-144 cell NE\oOIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2G0[WlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE46ODZ6NjFOwG0> M2i4[XNCVkeHUh?=
HUTU-80 cell NVOwU5VoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXjmR2xxUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OEm4OkDPxE1? NWHtWGI4W0GQR1XS
IST-MEL1 cell NFTBVWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmPFTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXMNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMzNjlyOE[g{txO M3HpRnNCVkeHUh?=
IST-SL1 cell NX32doVyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mm\QTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4yPzB5OTFOwG0> MkDjV2FPT0WU
IST-SL2 cell NEXSSWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorqTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> M{\x[XNCVkeHUh?=
K052 cell NXmwV3Y6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGS2R4pKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> NWG1b5VbW0GQR1XS
K5 cell NX:5OIo1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVPQT|VNUW6qaXLpeIlwdiCxZjDoeY1idiCNNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOzMlU6OTVizszN MVzTRW5ITVJ?
KALS-1 cell M2O5fGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXv4dZhXUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQS5|OU[5JO69VQ>? M4LtTHNCVkeHUh?=
KARPAS-422 cell MkDRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWHJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20NlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Oi57MUSyJO69VQ>? MVfTRW5ITVJ?
KARPAS-45 cell M1TsPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn;FTY5pcWKrdHnvckBw\iCqdX3hckBMSVKSQWOtOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjFzMkS3JO69VQ>? NIqzTJdUSU6JRWK=
KE-37 cell NFu1U3FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64N|Uh|ryP M4\lZXNCVkeHUh?=
KG-1 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVXJcohq[mm2aX;uJI9nKGi3bXHuJGtINTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz65O|U4KM7:TR?= MWXTRW5ITVJ?
KGN cell NYjie|I6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnvWTY5pcWKrdHnvckBw\iCqdX3hckBMT05iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkW2O|QzKM7:TR?= MWTTRW5ITVJ?
KM12 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV\qenZuUW6qaXLpeIlwdiCxZjDoeY1idiCNTUGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42Ojl4NDFOwG0> NWTuNY9nW0GQR1XS
KMOE-2 cell MlvTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXnJcohq[mm2aX;uJI9nKGi3bXHuJGtOV0VvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOwMlQ2PDlizszN NH[zb4VUSU6JRWK=
KNS-42 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2XzRmlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUSyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE45OTlzNTFOwG0> NWHnTY94W0GQR1XS
KNS-81-FD cell NHHvT|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NY\IWpY3UW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtPFEuTkRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nz60NlYh|ryP NX3vcWVUW0GQR1XS
KS-1 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4rBOWlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA1PiEQvF2= MmrpV2FPT0WU
KU812 cell MofyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkGyTY5pcWKrdHnvckBw\iCqdX3hckBMXThzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlQ5PCEQvF2= M4PWWXNCVkeHUh?=
L-540 cell Mn3nS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUPJcohq[mm2aX;uJI9nKGi3bXHuJGwuPTRyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkCuO|Q1PSEQvF2= MXvTRW5ITVJ?
LAMA-84 cell Mn\qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX;FdZV5UW6qaXLpeIlwdiCxZjDoeY1idiCOQV3BMVg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwNke0NkDPxE1? NVr6ZpRpW0GQR1XS
LB1047-RCC cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUTJcohq[mm2aX;uJI9nKGi3bXHuJGxDOTB2Nz3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQC5|OEizJO69VQ>? M2j6U3NCVkeHUh?=
LB2241-RCC cell NH7VTXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETYV2pKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OVM3KM7:TR?= NUTxbIVuW0GQR1XS
LB2518-MEL cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF61VXNKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkWxPE1OTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkexOFk3|ryP NVG2PZJqW0GQR1XS
LB831-BLC cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2TQbWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ6M{GtRmxEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTFwMUeyOkDPxE1? Mor0V2FPT0WU
LB996-RCC cell NUPidYplT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFHrcGZKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lke0N|Eh|ryP Ml2zV2FPT0WU
LC4-1 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnu4TY5pcWKrdHnvckBw\iCqdX3hckBNSzRvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlg{PDFizszN MVXTRW5ITVJ?
LOUCY cell M3vBOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJGxQXUO\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6xOVI4PiEQvF2= MlPKV2FPT0WU
LOXIMVI cell NWjGNWt[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH;u[m9KdmirYnn0bY9vKG:oIHj1cYFvKEyRWFnNWmkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC5{MUKyJO69VQ>? NFq3RmFUSU6JRWK=
LS-123 cell Mn7LS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGDlS5BKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUGyN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjJ{NUig{txO MYPTRW5ITVJ?
LU-134-A cell NHnpXoxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4TocWlvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO0MWEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjF2ME[4JO69VQ>? Ml\WV2FPT0WU
LU-139 cell M3ruc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF\O[WxKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjJzODFOwG0> MoDkV2FPT0WU
LXF-289 cell MoX0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{41OzVzzszN NW\XSGJpW0GQR1XS
MC116 cell NFLObmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml7LTY5pcWKrdHnvckBw\iCqdX3hckBOSzFzNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS1MlA5PDFizszN NWXPWXJPW0GQR1XS
MDA-MB-134-VI cell MoPWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmfnTY5pcWKrdHnvckBw\iCqdX3hckBOTEFvTVKtNVM1NV[LIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNlQ5PiEQvF2= MUnTRW5ITVJ?
MFH-ino cell M{TFd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mk\0TY5pcWKrdHnvckBw\iCqdX3hckBOTkhvaX7vJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43PDN6MzFOwG0> NH:5WWNUSU6JRWK=
MHH-NB-11 cell M{DKTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGfFVIJKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3ORk0yOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwME[2PUDPxE1? M1j1fHNCVkeHUh?=
ML-2 cell M2[yOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFO5U2xKdmirYnn0bY9vKG:oIHj1cYFvKE2OLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlQxOzB2IN88US=> M1fzTnNCVkeHUh?=
MOLT-13 cell MnrPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NECzd2dKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStNVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjR|NkWzJO69VQ>? MXXTRW5ITVJ?
MOLT-16 cell MlzGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4jXbmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTFzNkOg{txO MXPTRW5ITVJ?
MOLT-4 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV;KRXU6UW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC52MUK0JO69VQ>? MkDJV2FPT0WU
MPP-89 cell M2DMbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1LY[2lvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zPTl{MjFOwG0> MnznV2FPT0WU
MRK-nu-1 cell NEnQenJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkXPTY5pcWKrdHnvckBw\iCqdX3hckBOWktvboWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPTd3N{Kg{txO NGXzcnFUSU6JRWK=
MSTO-211H cell MoWwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> NWmwXHM6W0GQR1XS
MV-4-11 cell MkXNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIC4O3ZKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF|OUG1JO69VQ>? MX3TRW5ITVJ?
NALM-6 cell M3LGZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIfmRYFKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPTZzMEmg{txO NFjUUnRUSU6JRWK=
NB1 cell M4q1[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHXrXmFKdmirYnn0bY9vKG:oIHj1cYFvKE6EMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPFQ{PjlizszN Ml3SV2FPT0WU
NB10 cell NHHpNnpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYPnbZJiUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yOzlzNTFOwG0> M3HmbnNCVkeHUh?=
NB12 cell NXTacVYzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVTXboZ6UW6qaXLpeIlwdiCxZjDoeY1idiCQQkGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvPTZ3NjFOwG0> MkC4V2FPT0WU
NB13 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnHvTY5pcWKrdHnvckBw\iCqdX3hckBPSjF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6zNVI4QCEQvF2= NGTESGhUSU6JRWK=
NB17 cell M4TlN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NETaZ2JKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlU5ODVzIN88US=> MnH3V2FPT0WU
NB6 cell Ml;1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVyxbJNEUW6qaXLpeIlwdiCxZjDoeY1idiCQQk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU6OTF2IN88US=> NFLqNWJUSU6JRWK=
NCCIT cell NELPXYNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn;ETY5pcWKrdHnvckBw\iCqdX3hckBPS0OLVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSxMlg1PTNizszN MUTTRW5ITVJ?
NCI-H1155 cell M3zyRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHzGVpFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVE2PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF2LkO0NFgh|ryP NWDhd2NsW0GQR1XS
NCI-H1304 cell NEDteIRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO NV;5NmF{W0GQR1XS
NCI-H1355 cell M1P4dGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEe3[o1KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVM2PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwOUSxNUDPxE1? NWX0VpoxW0GQR1XS
NCI-H1395 cell Mn7XS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF\3bpdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVM6PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3PVUh|ryP M1G4V3NCVkeHUh?=
NCI-H1417 cell NUH4e5p2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEnYOJRKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVQyPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNke1NlIh|ryP NHzySZhUSU6JRWK=
NCI-H1436 cell NYTPcI1ST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4rVVmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFM3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy56NEGwNUDPxE1? NYXjbZRDW0GQR1XS
NTERA-S-cl-D1 cell NYXqWnJGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2nTWGlvcGmkaYTpc44hd2ZiaIXtZY4hVlSHUlGtV{1kdC2GMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlg6OzVizszN NGfzTnBUSU6JRWK=
JiyoyeP-2003 cell Mnn3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXW2UYVmUW6qaXLpeIlwdiCxZjDoeY1idiCMaYnvfYVRNTJyMEOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43Ojh2IN88US=> M{XOVHNCVkeHUh?=

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
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  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID