GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

Size Price Stock Quantity  
USD 97 In stock
USD 397 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NGL0bGpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFXENWxKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVU5OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF6Lki0O|ch|ryP NUD5WnREW0GQR1XS
NCI-H1694 NW\rdXFlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[5OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njh5NEmg{txO NGfKeJZUSU6JRWK=
NCI-H1963 M4DKUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M17aPGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixPVY{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5{N{izPUDPxE1? MVrTRW5ITVJ?
NCI-H2081 NUHmN4J1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2fpWWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwNkC0OEDPxE1? MVHTRW5ITVJ?
NCI-H209 NEDLVY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2nFVmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi54MkeyJO69VQ>? MV7TRW5ITVJ?
NCI-H2107 Mk\ZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGPaRWFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlExPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ3Lk[1OlEh|ryP M3u2c3NCVkeHUh?=
NCI-H2126 M{W1cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXTYUHExUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyOjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkWwOFI3KM7:TR?= NUfxe4RpW0GQR1XS
NCI-H2171 Mli1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH\ON|hKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE4OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwOUW5N|ch|ryP MXjTRW5ITVJ?
NCI-H2227 Mn\wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlnETY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKyNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04Njh6NkG2JO69VQ>? M3XJUnNCVkeHUh?=
NCI-H524 M3;5Z2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVrscVhJUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFUzPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3OlMh|ryP NYrPWYpTW0GQR1XS
NCI-H526 MnOxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2rNTWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC53NEOxJO69VQ>? NE\s[lJUSU6JRWK=
NCI-H720 MnrTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M121e2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NlAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjR3MU[xJO69VQ>? NXO1WW9HW0GQR1XS
NMC-G1 NFrC[5JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NULsXoE3UW6qaXLpeIlwdiCxZjDoeY1idiCQTVOtS|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS5yNUe4JO69VQ>? NGK1VnFUSU6JRWK=
NOS-1 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{PXemlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlgzOjl2IN88US=> MXzTRW5ITVJ?
OCI-AML2 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnXVTY5pcWKrdHnvckBw\iCqdX3hckBQS0lvQV3MNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjl2OU[g{txO NFK2[Y1USU6JRWK=
OCUB-M cell NGLoUJdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVzjPJJHUW6qaXLpeIlwdiCxZjDoeY1idiCRQ2XCMW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy5{MEGg{txO MYjTRW5ITVJ?
ONS-76 cell NIDi[I1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mk\jTY5pcWKrdHnvckBw\iCqdX3hckBQVlNvN{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46OTlzIN88US=> M4m3NXNCVkeHUh?=
OS-RC-2 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU\jeHNCUW6qaXLpeIlwdiCxZjDoeY1idiCRUz3SR{0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwMUm1JO69VQ>? MmKwV2FPT0WU
OVCAR-4 cell NFXDS|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\SSIF5UW6qaXLpeIlwdiCxZjDoeY1idiCRVlPBVk01KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC55MUiwPEDPxE1? Ml[yV2FPT0WU
P30-OHK cell M1excWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;5XotiUW6qaXLpeIlwdiCxZjDoeY1idiCSM{CtU2hMKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py54Mki3O{DPxE1? NIT2OYtUSU6JRWK=
P30-OHK cell NWnoV2ZOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NITuXJBKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvODR7NUSg{txO NIPScFdUSU6JRWK=
PSN1 cell MlnTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGLoc29KdmirYnn0bY9vKG:oIHj1cYFvKFCVTkGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22MlIzOTJ4IN88US=> NWrSd5hyW0GQR1XS
QIMR-WIL cell M4PIfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2HSeGlvcGmkaYTpc44hd2ZiaIXtZY4hWUmPUj3XTWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjR7MEC0JO69VQ>? NF7sSXBUSU6JRWK=
RCC10RGB cell Mlz6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnFZYxKdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOUCzOkDPxE1? MmDmV2FPT0WU
RKO cell NIrKOW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF70XZdKdmirYnn0bY9vKG:oIHj1cYFvKFKNTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlU3PjJizszN NIr2OphUSU6JRWK=
RL95-2 cell MljqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUfJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlY4KM7:TR?= MnjFV2FPT0WU
RPMI-6666 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4Ow[mlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? MYnTRW5ITVJ?
RPMI-8402 cell NVqwV|dZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NELNW5NKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? MV\TRW5ITVJ?
RXF393 cell MnrNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFjiTI9KdmirYnn0bY9vKG:oIHj1cYFvKFK[RkO5N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzl|IN88US=> Ml[5V2FPT0WU
Ramos-2G6-4C10 cell NEHqO5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2jjfGlvcGmkaYTpc44hd2ZiaIXtZY4hWmGvb4OtNmc3NTSFMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlM2PyEQvF2= Mk[2V2FPT0WU
SCLC-21H cell NFzpWJhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkXtTY5pcWKrdHnvckBw\iCqdX3hckBUS0yFLUKxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjFzNEmg{txO NWe1[|ZrW0GQR1XS
SF126 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVnLS|ZPUW6qaXLpeIlwdiCxZjDoeY1idiCVRkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh|MkJOwG0> M32x[3NCVkeHUh?=
SF268 cell NWPSU29ZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX3NUJlTUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOjNzOEOg{txO NE\qTnVUSU6JRWK=
SF539 cell M1\VS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnjDTY5pcWKrdHnvckBw\iCqdX3hckBUTjV|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNlg3PjFizszN NFjFZZpUSU6JRWK=
SH-4 cell M2Ppbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUnJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= M4jxR3NCVkeHUh?=
SIG-M5 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJHNKTy2PNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGxMlczPTlizszN Mnz3V2FPT0WU
SJSA-1 cell NEfrboRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUjJcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFQ2OjZizszN NWTyU4VnW0GQR1XS
SK-LMS-1 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFzqfldKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzNV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwNUm2OUDPxE1? MlrtV2FPT0WU
SK-MM-2 cell NXLkb|dYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPQSYNKdmirYnn0bY9vKG:oIHj1cYFvKFONLV3NMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Oi5|NEC1JO69VQ>? NHfKU5FUSU6JRWK=
SK-N-DZ cell M3T4d2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1GwTGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTj3EXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPDh|MUSg{txO M1nBZXNCVkeHUh?=
SK-NEP-1 cell NIe0S3RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MorQTY5pcWKrdHnvckBw\iCqdX3hckBUUy2QRWCtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjV2NU[g{txO NWHRbI5OW0GQR1XS
SK-PN-DW cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGXXXVRKdmirYnn0bY9vKG:oIHj1cYFvKFONLWDOMWRYKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOUezOkDPxE1? MoPHV2FPT0WU
SNB75 cell NIi2[pJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHfvRlJKdmirYnn0bY9vKG:oIHj1cYFvKFOQQke1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE4xPzd|NzFOwG0> Mn:0V2FPT0WU
SR cell NIfHcYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYK3fWtYUW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAxOTN5IN88US=> NYrhPXNpW0GQR1XS
SU-DHL-1 cell MkfPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVH0fGJpUW6qaXLpeIlwdiCxZjDoeY1idiCVVT3ETGwuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{LkezN|Yh|ryP Mn3lV2FPT0WU
SW684 cell NEm5[YZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MULJcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNFEyKM7:TR?= M1WweHNCVkeHUh?=
SW872 cell Mo\BS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUHJcohq[mm2aX;uJI9nKGi3bXHuJHNYQDd{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64PFY2PiEQvF2= MWDTRW5ITVJ?
SW962 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M37hbGlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk44PTJzIN88US=> NFeyRWNUSU6JRWK=
697 cell NETyemhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJFY6PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMkm5NUDPxE1? M1jhdHNCVkeHUh?=
8-MG-BA cell NU\0fYhxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2nwdGlvcGmkaYTpc44hd2ZiaIXtZY4hQC2PRz3CRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjB5OUOg{txO NGj5bIFUSU6JRWK=
A101D cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIjkSFFKdmirYnn0bY9vKG:oIHj1cYFvKEFzMEHEJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45PzB|NDFOwG0> M1vLW3NCVkeHUh?=
ACN cell M{ezVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGjxS5hKdmirYnn0bY9vKG:oIHj1cYFvKEGFTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKxMlQ{QDdizszN Mmq3V2FPT0WU
AM-38 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{nMcWlvcGmkaYTpc44hd2ZiaIXtZY4hSU1vM{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI3OzJ5IN88US=> MUHTRW5ITVJ?
ATN-1 cell MlqyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGFVVi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkSuO|U2PSEQvF2= NFXGfJdUSU6JRWK=
BB30-HNC cell Ml6zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYnJcohq[mm2aX;uJI9nKGi3bXHuJGJDOzBvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOjV|MjFOwG0> MlvmV2FPT0WU
BB49-HNC cell NELxPW5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHK3NWRKdmirYnn0bY9vKG:oIHj1cYFvKEKENEmtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMEe4PUDPxE1? NGnkXY5USU6JRWK=
human BC-1 cell NGnnUWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mk\STY5pcWKrdHnvckBw\iCqdX3hckBDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65O|ExPyEQvF2= NH[4bo9USU6JRWK=
BE-13 cell NXrY[2RzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NELxN3hKdmirYnn0bY9vKG:oIHj1cYFvKEKHLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDB6Md88US=> NF[yRolUSU6JRWK=
BL-70 cell NGr3cZNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX;Ob3NRUW6qaXLpeIlwdiCxZjDoeY1idiCETD23NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPDB5MEOg{txO Ml6zV2FPT0WU
BV-173 cell NV;QUIZmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NETUVHNKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh6NUmg{txO MXnTRW5ITVJ?
Becker cell MkTxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NY\0TpIxUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NUS1JO69VQ>? MlvBV2FPT0WU
CAL-148 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1jmOWlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO NUX5ZVFkW0GQR1XS
TE-10 cell MnXoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NELWc2RKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDR{MzFOwG0> M3frVnNCVkeHUh?=
TE-12 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX3Jcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{KuOFEyPCEQvF2= NEHwZ3BUSU6JRWK=
TE-8 cell NHXm[FNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlL6TY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOlA5QSEQvF2= M1PzN3NCVkeHUh?=
TE-9 cell NVj5WWp[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mk\JTY5pcWKrdHnvckBw\iCqdX3hckBVTS17IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{[uOlM5OSEQvF2= MVfTRW5ITVJ?
TGW cell NX3NcocxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVvi[XBUUW6qaXLpeIlwdiCxZjDoeY1idiCWR2egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4{PTd5IN88US=> NX7jUFA{W0GQR1XS
UACC-257 cell NF;WPY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3vCSGlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdyNkK1JO69VQ>? NUnUVFFLW0GQR1XS
WSU-NHL cell NGD4cFdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVHQRox[UW6qaXLpeIlwdiCxZjDoeY1idiCZU2WtUmhNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjdwMUmwO{DPxE1? NH\TV3dUSU6JRWK=
no-10 cell Ml;VS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV3VV2tIUW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjZ6NE[g{txO MVrTRW5ITVJ?
no-11 cell NG[5ZXVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2\jSGlvcGmkaYTpc44hd2ZiaIXtZY4hdm9vMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{4xOjZ|IN88US=> M3PzRXNCVkeHUh?=
CAS-1 cell M1LTXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIHW[41KdmirYnn0bY9vKG:oIHj1cYFvKEODUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PDdizszN MnHIV2FPT0WU
CCRF-CEM cell NV3tXGxRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXLJcohq[mm2aX;uJI9nKGi3bXHuJGNEWkZvQ1XNJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE43PTN7MjFOwG0> Ml3yV2FPT0WU
CMK cell Ml:3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGNOUyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEGzNlMh|ryP MYDTRW5ITVJ?
COLO-829 cell NEnVfmJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPDJ{NjFOwG0> NIfkdW5USU6JRWK=
COR-L279 cell NFi5UIVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlS5TY5pcWKrdHnvckBw\iCqdX3hckBEV1JvTEK3PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvODd|ODFOwG0> M4Hu[nNCVkeHUh?=
CP66-MEL cell M4HV[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH7RNIFKdmirYnn0bY9vKG:oIHj1cYFvKEOSNk[tUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzZwNUS5O{DPxE1? MWDTRW5ITVJ?
CRO-AP2 cell NX7XdGhZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MojSTY5pcWKrdHnvckBw\iCqdX3hckBEWk9vQWCyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{PjB6ODFOwG0> MX7TRW5ITVJ?
CTV-1 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWrJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= MXzTRW5ITVJ?
Calu-6 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYHJcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlU5PiEQvF2= NGTjUVhUSU6JRWK=
D-247MG cell NGPNS|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGQuOjR5TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlYzQDF2IN88US=> NG\IfY9USU6JRWK=
D-263MG cell NFuyNmhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA5PTB7IN88US=> M4LoOnNCVkeHUh?=
D-336MG cell MmfmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXPVS5BlUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54Mki1OEDPxE1? NIixd3VUSU6JRWK=
D-392MG cell NGfIWFlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkS4TY5pcWKrdHnvckBw\iCqdX3hckBFNTN7Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41OzB|OTFOwG0> NXvOXXlqW0GQR1XS
D-502MG cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVHIe4pZUW6qaXLpeIlwdiCxZjDoeY1idiCGLUWwNm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC53M{S5NkDPxE1? NGP2[HNUSU6JRWK=
D-542MG cell MlnzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVLrSIRUUW6qaXLpeIlwdiCxZjDoeY1idiCGLUW0Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwM{G1NkDPxE1? NYTvTGhEW0GQR1XS
DB cell MlvHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4LHN2lvcGmkaYTpc44hd2ZiaIXtZY4hTEJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Nz6xOFE4KM7:TR?= MmjzV2FPT0WU
DEL cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYXJcohq[mm2aX;uJI9nKGi3bXHuJGRGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwMEG4PVgh|ryP Mnn5V2FPT0WU
DMS-114 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkTHTY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUG0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFkvQDR4ODFOwG0> M4nzV3NCVkeHUh?=
DMS-153 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUfJcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zNUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk46QTJ|IN88US=> NXHMOXcyW0GQR1XS
DOHH-2 cell NGXxRm1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml2xTY5pcWKrdHnvckBw\iCqdX3hckBFV0iKLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlIzPzZ2IN88US=> MmHGV2FPT0WU
DSH1 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{HqZWlvcGmkaYTpc44hd2ZiaIXtZY4hTFOKMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuOFM3OjNizszN NEjIXnJUSU6JRWK=
Daudi cell M3;lTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX7iZXdpUW6qaXLpeIlwdiCxZjDoeY1idiCGYYXkbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvODl6MEKg{txO M4S5Z3NCVkeHUh?=
EC-GI-10 cell NVPKWXlzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV3mcGR{UW6qaXLpeIlwdiCxZjDoeY1idiCHQz3HTU0yOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR2LkK1PFkh|ryP NE[0N5NUSU6JRWK=
ECC4 cell MmnmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGPLSY1KdmirYnn0bY9vKG:oIHj1cYFvKEWFQ{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk4yQDl4IN88US=> MmDnV2FPT0WU
EM-2 cell M4nwdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEDXem5KdmirYnn0bY9vKG:oIHj1cYFvKEWPLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlQ2PTl2IN88US=> MkHrV2FPT0WU
ES1 cell NV3xUmZbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7Oc4RKdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN NGTMTllUSU6JRWK=
ES3 cell NH3TeFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\Fd2hPUW6qaXLpeIlwdiCxZjDoeY1idiCHU{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk41PzJ7IN88US=> MlHUV2FPT0WU
ES4 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1;vVmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVk2KM7:TR?= NG\scJdUSU6JRWK=
ES6 cell M{XXRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVzxb2RDUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1PzN|IN88US=> NXH1ZZBoW0GQR1XS
ES7 cell NGnn[WdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoC2TY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkKzNVI1KM7:TR?= MWfTRW5ITVJ?
ES8 cell MlfxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofVTY5pcWKrdHnvckBw\iCqdX3hckBGWzhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkixPVI1KM7:TR?= NXrLOGFZW0GQR1XS
EW-18 cell NIPxO2JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3H2d2lvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43PzV7IN88US=> NIjCT3JUSU6JRWK=
EW-22 cell M1\ncGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVnJcohq[mm2aX;uJI9nKGi3bXHuJGVYNTJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuO|k1PyEQvF2= MV3TRW5ITVJ?
GCIY cell NYK5emFlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWfJcohq[mm2aX;uJI9nKGi3bXHuJGdEUVliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkiwN|g6KM7:TR?= MWjTRW5ITVJ?
GDM-1 cell MmTUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MknETY5pcWKrdHnvckBw\iCqdX3hckBITE1vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuN|kyQTZizszN MVLTRW5ITVJ?
GI-1 cell Mn3KS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWfJcohq[mm2aX;uJI9nKGi3bXHuJGdKNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwOVI{KM7:TR?= MYHTRW5ITVJ?
GI-ME-N cell NGHmTmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUDJcohq[mm2aX;uJI9nKGi3bXHuJGdKNU2HLV6gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1QTVzIN88US=> Ml24V2FPT0WU
GR-ST cell M1XtOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWfOS25TUW6qaXLpeIlwdiCxZjDoeY1idiCJUj3TWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njd7MEKg{txO NYGzUmFIW0GQR1XS
GT3TKB cell Mln0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGXXS4FKdmirYnn0bY9vKG:oIHj1cYFvKEeWM2TLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPjB|OEmg{txO NYL5cI9QW0GQR1XS
HAL-01 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHi2R2ZKdmirYnn0bY9vKG:oIHj1cYFvKEiDTD2wNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPjl5MUKg{txO M3noOHNCVkeHUh?=
HCC1599 cell NHPIcpBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUnJcohq[mm2aX;uJI9nKGi3bXHuJGhESzF3OUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zO{43ODFzIN88US=> NXzh[mJmW0GQR1XS
HCC2218 cell Mor0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGPB[nRKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{KyNVgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy5|OEO0JO69VQ>? M2LWfXNCVkeHUh?=
HD-MY-Z cell NF;hVm1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MknhTY5pcWKrdHnvckBw\iCqdX3hckBJTC2PWT3aJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlUvOjF2NjFOwG0> MW\TRW5ITVJ?
HL-60 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{HLRmlvcGmkaYTpc44hd2ZiaIXtZY4hUExvNkCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk4zOTF2IN88US=> MoOzV2FPT0WU
HOP-62 cell NYPkNFZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH3USJRKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{Njl3Mkeg{txO M{\XRnNCVkeHUh?=
HT cell NGKxd2dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3PrPWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkS0N|IyKM7:TR?= MVHTRW5ITVJ?
HT-144 cell NVHDW4U{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGT6NnRKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUG0OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTB4OE[g{txO NUi1O4R4W0GQR1XS
HUTU-80 cell M1m4NGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{jadWlvcGmkaYTpc44hd2ZiaIXtZY4hUFWWVT24NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPzh7OE[g{txO MmrGV2FPT0WU
IST-MEL1 cell NYnwVmtGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUTMdGxNUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkmwPFYh|ryP Mor3V2FPT0WU
IST-SL1 cell Ml\4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmDNTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4yPzB5OTFOwG0> Mnz3V2FPT0WU
IST-SL2 cell M2njdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mm\UTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> MnPpV2FPT0WU
K052 cell NFjsN5FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1;WUmlvcGmkaYTpc44hd2ZiaIXtZY4hUzB3MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuO|U{ODFizszN MWPTRW5ITVJ?
K5 cell NEPpTmVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{n6SmlvcGmkaYTpc44hd2ZiaIXtZY4hUzViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mz61PVE2KM7:TR?= NInrXZNUSU6JRWK=
KALS-1 cell M4PRWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVLZUpYxUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQS5|OU[5JO69VQ>? M2DWSXNCVkeHUh?=
KARPAS-422 cell M3noTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1vV[mlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP MUjTRW5ITVJ?
KARPAS-45 cell M1HuNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUjJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTF{NEeg{txO NGrRUmdUSU6JRWK=
KE-37 cell M4fIT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64N|Uh|ryP MVfTRW5ITVJ?
KG-1 cell M3X6c2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYPi[5JpUW6qaXLpeIlwdiCxZjDoeY1idiCNRz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvQTd3NzFOwG0> MmPWV2FPT0WU
KGN cell NYLBPGlXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3vwbWlvcGmkaYTpc44hd2ZiaIXtZY4hU0eQIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD61Olc1OiEQvF2= Ml7UV2FPT0WU
KM12 cell NYPITph7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGtOOTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkWyPVY1KM7:TR?= NVPkZ4dQW0GQR1XS
KMOE-2 cell NX\Ud4dlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn65TY5pcWKrdHnvckBw\iCqdX3hckBMVU:HLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE41PTR7IN88US=> M2HOWHNCVkeHUh?=
KNS-42 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnjpTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvNEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlgyQTF3IN88US=> M{nOc3NCVkeHUh?=
KNS-81-FD cell NX7iVHdyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHL2UZBKdmirYnn0bY9vKG:oIHj1cYFvKEuQUz24NU1HTCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN5LkSyOkDPxE1? MVXTRW5ITVJ?
KS-1 cell NVruXoRKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3fwWGlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA1PiEQvF2= Ml\0V2FPT0WU
KU812 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEjBUVVKdmirYnn0bY9vKG:oIHj1cYFvKEuXOEGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPDh2IN88US=> M3HqfHNCVkeHUh?=
L-540 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHjNbHZKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR2NTFOwG0> NUP4TmtwW0GQR1XS
LAMA-84 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3i2e2lvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjZ5NEKg{txO MXHTRW5ITVJ?
LB1047-RCC cell M{e2Rmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVHWPYtMUW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkiuN|g5OyEQvF2= NHPLW|ZUSU6JRWK=
LB2241-RCC cell M4XSRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGDwUZFKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OVM3KM7:TR?= MVHTRW5ITVJ?
LB2518-MEL cell NHfZeIRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYTJcohq[mm2aX;uJI9nKGi3bXHuJGxDOjVzOD3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjdzNEm2{txO MmL6V2FPT0WU
LB831-BLC cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX:4V5hjUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT6xO|I3KM7:TR?= NYW3OGJFW0GQR1XS
LB996-RCC cell Mlv5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH;Lb4pKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lke0N|Eh|ryP MYTTRW5ITVJ?
LC4-1 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2q4S2lvcGmkaYTpc44hd2ZiaIXtZY4hVEN2LUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk45OzRzIN88US=> NFK3RWpUSU6JRWK=
LOUCY cell MnHSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXLJcohq[mm2aX;uJI9nKGi3bXHuJGxQXUO\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6xOVI4PiEQvF2= NXrkbol6W0GQR1XS
LOXIMVI cell MnfxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnqWXVKdmirYnn0bY9vKG:oIHj1cYFvKEyRWFnNWmkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC5{MUKyJO69VQ>? M4nt[nNCVkeHUh?=
LS-123 cell M3PiU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{[2e2lvcGmkaYTpc44hd2ZiaIXtZY4hVFNvMUKzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvOjJ3ODFOwG0> M{LNeXNCVkeHUh?=
LU-134-A cell M{PG[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmLYTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{StRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOTRyNkig{txO M1HNR3NCVkeHUh?=
LU-139 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvkTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk4zOThizszN NE\P[2RUSU6JRWK=
LXF-289 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NI\3c4tKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy52M{Wx{txO MXLTRW5ITVJ?
MC116 cell M2GwZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXrJcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuNFg1OSEQvF2= NILPe3BUSU6JRWK=
MDA-MB-134-VI cell NYPPTotkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFfDdGxKdmirYnn0bY9vKG:oIHj1cYFvKE2GQT3NRk0yOzRvVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zPU4zPDh4IN88US=> M4TuV3NCVkeHUh?=
MFH-ino cell MmryS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUTJcohq[mm2aX;uJI9nKGi3bXHuJG1HUC2rbn:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY1Ozh|IN88US=> NIDPenpUSU6JRWK=
MHH-NB-11 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXjJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODZ4OTFOwG0> MV;TRW5ITVJ?
ML-2 cell NHrTclFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3iyRWlvcGmkaYTpc44hd2ZiaIXtZY4hVUxvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOFA{ODRizszN MkTQV2FPT0WU
MOLT-13 cell M3OzU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGqyXoRKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStNVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjR|NkWzJO69VQ>? MUTTRW5ITVJ?
MOLT-16 cell NX;pcFBQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWjJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlEyOTZ|IN88US=> MYrTRW5ITVJ?
MOLT-4 cell NHvufodIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0MlQyOjRizszN NHLi[lNUSU6JRWK=
MPP-89 cell MnPlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PLVmlvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zPTl{MjFOwG0> MoPTV2FPT0WU
MRK-nu-1 cell NIfh[|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{PmTGlvcGmkaYTpc44hd2ZiaIXtZY4hVVKNLX71MVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjV5NUeyJO69VQ>? MmXGV2FPT0WU
MSTO-211H cell MlPOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWjJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> NFztNG1USU6JRWK=
MV-4-11 cell NH3wbXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHnHbHZKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF|OUG1JO69VQ>? MUHTRW5ITVJ?
NALM-6 cell Moj0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofJTY5pcWKrdHnvckBw\iCqdX3hckBPSUyPLU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlU3OTB7IN88US=> NEKyWFZUSU6JRWK=
NB1 cell NIrW[2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3r0OWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz64OFM3QSEQvF2= MojuV2FPT0WU
NB10 cell MlzlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml\iTY5pcWKrdHnvckBw\iCqdX3hckBPSjFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xN|kyPSEQvF2= MVPTRW5ITVJ?
NB12 cell NWLt[2tTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH3DXWxKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOk42PjV4IN88US=> NXvYfWhmW0GQR1XS
NB13 cell NIryPGJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWnJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkOxNlc5KM7:TR?= NVHMcm1qW0GQR1XS
NB17 cell M4PnUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mmj6TY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= NG\4e5pUSU6JRWK=
NB6 cell M3fpbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHnTNZpKdmirYnn0bY9vKG:oIHj1cYFvKE6ENjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVkyOTRizszN M2rMOnNCVkeHUh?=
NCCIT cell M3Hhbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXTOfVlCUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1PJWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQyNjh2NUOg{txO NHHyW3NUSU6JRWK=
NCI-H1155 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2HnfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixNVU2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTRwM{SwPEDPxE1? NWTET2RRW0GQR1XS
NCI-H1304 cell NXLmd|QzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV3Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO M3LuZnNCVkeHUh?=
NCI-H1355 cell NYfIToNTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{HpdWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC57NEGxJO69VQ>? MVLTRW5ITVJ?
NCI-H1395 cell M{O3bmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmDVTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56N{m1JO69VQ>? M1zMdXNCVkeHUh?=
NCI-H1417 cell M1LuPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlLFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG0NVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02NjZ5NUKyJO69VQ>? NGLLToFUSU6JRWK=
NCI-H1436 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnteIRzUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE1OzZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lki0NVAyKM7:TR?= MYXTRW5ITVJ?
NTERA-S-cl-D1 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDnPGMzUW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvQDl|NTFOwG0> Mm\MV2FPT0WU
JiyoyeP-2003 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3n3WmlvcGmkaYTpc44hd2ZiaIXtZY4hUmm7b4nlVE0zODB|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{[uOlI5PCEQvF2= MXLTRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
+ Expand
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

ROCK Signaling Pathway Map

Related ROCK Products0

Tags: buy GSK269962A HCl | GSK269962A HCl supplier | purchase GSK269962A HCl | GSK269962A HCl cost | GSK269962A HCl manufacturer | order GSK269962A HCl | GSK269962A HCl distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID