GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NWH3[251T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1zoN2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOVgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOES3O{DPxE1? NXjlfZg1W0GQR1XS
NCI-H1694 MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmHtTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG2PVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPC56N{S5JO69VQ>? NX32fFVkW0GQR1XS
NCI-H1963 M4np[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1HsUGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixPVY{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5{N{izPUDPxE1? NWHjZlFXW0GQR1XS
NCI-H2081 NGD0[Y9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXrJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC4NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM1NjZyNESg{txO MVTTRW5ITVJ?
NCI-H209 MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFPjfnhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlA6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwNkK3NkDPxE1? MnPkV2FPT0WU
NCI-H2107 MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4C0OmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVA4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwNkW2NUDPxE1? M3LnV3NCVkeHUh?=
NCI-H2126 MnTRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmjBTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjVyNEK2JO69VQ>? NGCzWlBUSU6JRWK=
NCI-H2171 NYPFdGZ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3GxeGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVcyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC57NUmzO{DPxE1? M{PNWHNCVkeHUh?=
NCI-H2227 NVz3VZdkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mnn5TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKyNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04Njh6NkG2JO69VQ>? NFnXOoJUSU6JRWK=
NCI-H524 MlXpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNUK0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDd4MzFOwG0> MV7TRW5ITVJ?
NCI-H526 MlnPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmLaTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV2M{Gg{txO NFLrOY1USU6JRWK=
NCI-H720 MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUXGeG9YUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFczOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwNEWxOlEh|ryP NX7xbZlTW0GQR1XS
NMC-G1 NIfiZ4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG1MlA2PzhizszN NFLDdY5USU6JRWK=
NOS-1 cell MnT0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3fOVWlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlgzOjl2IN88US=> NGK3eWJUSU6JRWK=
OCI-AML2 cell NYPj[IptT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXXxZnNCUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkm0PVYh|ryP M{KyenNCVkeHUh?=
OCUB-M cell MojnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEX3NJZKdmirYnn0bY9vKG:oIHj1cYFvKE:FVVKtUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjJyMTFOwG0> MVnTRW5ITVJ?
ONS-76 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4\OTGlvcGmkaYTpc44hd2ZiaIXtZY4hV06VLUe2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTF7MTFOwG0> MoDGV2FPT0WU
OS-RC-2 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWLJcohq[mm2aX;uJI9nKGi3bXHuJG9UNVKFLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok4yQTVizszN MWfTRW5ITVJ?
OVCAR-4 cell NIT3U5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M13ocmlvcGmkaYTpc44hd2ZiaIXtZY4hV1[FQWKtOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPzF6MEig{txO MVXTRW5ITVJ?
P30-OHK cell MnLzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVPENJpyUW6qaXLpeIlwdiCxZjDoeY1idiCSM{CtU2hMKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py54Mki3O{DPxE1? MX7TRW5ITVJ?
P30-OHK cell NV3Ie491T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVjJcohq[mm2aX;uJI9nKGi3bXHuJHBHNTN6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNFQ6PTRizszN NUPQ[WRQW0GQR1XS
PSN1 cell M1PYVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXLJcohq[mm2aX;uJI9nKGi3bXHuJHBUVjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkKyNVI3KM7:TR?= MnjRV2FPT0WU
QIMR-WIL cell NWTEe|R4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEDQbpNKdmirYnn0bY9vKG:oIHj1cYFvKFGLTWKtW2lNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC52OUCwOEDPxE1? MkHmV2FPT0WU
RCC10RGB cell M{nOOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mkj1TY5pcWKrdHnvckBw\iCqdX3hckBTS0NzMGLHRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjlyM{[g{txO NH;h[pJUSU6JRWK=
RKO cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1jxemlvcGmkaYTpc44hd2ZiaIXtZY4hWkuRIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUCuOVY3OiEQvF2= NVP1V2pOW0GQR1XS
RL95-2 cell NIPz[HdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWTJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlY4KM7:TR?= MlXlV2FPT0WU
RPMI-6666 cell NIDOS|dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2fHVGlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? M1\ofXNCVkeHUh?=
RPMI-8402 cell NXT1fmR4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV7aUHpiUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg1ODJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkW4OVYh|ryP MmfqV2FPT0WU
RXF393 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFz2clBKdmirYnn0bY9vKG:oIHj1cYFvKFK[RkO5N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzl|IN88US=> NV\xZZBmW0GQR1XS
Ramos-2G6-4C10 cell Mkj2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NE\wfFVKdmirYnn0bY9vKG:oIHj1cYFvKFKjbX;zMVJIPi12Q{GwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4{PTdizszN NFeyfmhUSU6JRWK=
SCLC-21H cell M2jCWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml\3TY5pcWKrdHnvckBw\iCqdX3hckBUS0yFLUKxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjFzNEmg{txO M4fjR3NCVkeHUh?=
SF126 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYjJcohq[mm2aX;uJI9nKGi3bXHuJHNHOTJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuPFMzOc7:TR?= MXzTRW5ITVJ?
SF268 cell NHzpcJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUDuPWl5UW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOjNzOEOg{txO NXPUOFVqW0GQR1XS
SF539 cell NITUSppIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmTxTY5pcWKrdHnvckBw\iCqdX3hckBUTjV|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNlg3PjFizszN MlnDV2FPT0WU
SH-4 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYG0b2tqUW6qaXLpeIlwdiCxZjDoeY1idiCVSD20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU44PTVyODFOwG0> NXO4dWNrW0GQR1XS
SIG-M5 cell M3foS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml[1TY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU44OjV7IN88US=> NFL2UpJUSU6JRWK=
SJSA-1 cell NXHwPZB{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYLJcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFQ2OjZizszN NXvkWHlCW0GQR1XS
SK-LMS-1 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUnXZYxiUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3MUXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkW5OlUh|ryP MofuV2FPT0WU
SK-MM-2 cell NXfoRYttT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUPvZ|JSUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NUU0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwM{SwOUDPxE1? NEnlRXpUSU6JRWK=
SK-N-DZ cell NF\CTlBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M36zeGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTj3EXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPDh|MUSg{txO NIHwS25USU6JRWK=
SK-NEP-1 cell M{D4dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmrCTY5pcWKrdHnvckBw\iCqdX3hckBUUy2QRWCtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjV2NU[g{txO NYraOJhoW0GQR1XS
SK-PN-DW cell NGnCeHZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGfkdodKdmirYnn0bY9vKG:oIHj1cYFvKFONLWDOMWRYKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOUezOkDPxE1? MlnaV2FPT0WU
SNB75 cell M4fOfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn\VTY5pcWKrdHnvckBw\iCqdX3hckBUVkJ5NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuNFc4OzdizszN MoS1V2FPT0WU
SR cell MlXxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUDJcohq[mm2aX;uJI9nKGi3bXHuJHNTKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMECxN|ch|ryP MWLTRW5ITVJ?
SU-DHL-1 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXHlO5pHUW6qaXLpeIlwdiCxZjDoeY1idiCVVT3ETGwuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{LkezN|Yh|ryP M2nNXnNCVkeHUh?=
SW684 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml\JTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= MnHEV2FPT0WU
SW872 cell M2nkZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWPreIdVUW6qaXLpeIlwdiCxZjDoeY1idiCVV{i3NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDh4NU[g{txO M2jn[3NCVkeHUh?=
SW962 cell NW\2[o5ST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIP2TFBKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPzV{MTFOwG0> NHK4VHpUSU6JRWK=
697 cell MkTyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXr1NYd5UW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI6QTFizszN NIjmXFNUSU6JRWK=
8-MG-BA cell M17wV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUnVd2UyUW6qaXLpeIlwdiCxZjDoeY1idiB6LV3HMWJCKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjNwMEe5N{DPxE1? Mlu0V2FPT0WU
A101D cell NEXObYtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUjI[XNMUW6qaXLpeIlwdiCxZjDoeY1idiCDMUCxSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDdyM{Sg{txO MX3TRW5ITVJ?
ACN cell M3zIPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NY\1WINCUW6qaXLpeIlwdiCxZjDoeY1idiCDQ16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNU41Ozh5IN88US=> NUP6c3AyW0GQR1XS
AM-38 cell M1W1O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWTJcohq[mm2aX;uJI9nKGi3bXHuJGFONTN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz6yOlMzPyEQvF2= Mmf3V2FPT0WU
ATN-1 cell M2X2PWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYKzWI9[UW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd3NUWg{txO NH70e2JUSU6JRWK=
BB30-HNC cell NHvpOHhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4DHSWlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{NUOyJO69VQ>? NGHpVnFUSU6JRWK=
BB49-HNC cell NILWNnJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVHYfFNJUW6qaXLpeIlwdiCxZjDoeY1idiCEQkS5MWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEC3PFkh|ryP MorNV2FPT0WU
human BC-1 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVXJcohq[mm2aX;uJI9nKGi3bXHuJGJENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lkm3NVA4KM7:TR?= M1;3ZnNCVkeHUh?=
BE-13 cell NULieoE1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2[4NmlvcGmkaYTpc44hd2ZiaIXtZY4hSkVvMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE1ODhzzszN M1zMO3NCVkeHUh?=
BL-70 cell NGPQVWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NE[1eWpKdmirYnn0bY9vKG:oIHj1cYFvKEKOLUewJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODdyMzFOwG0> M2nZb3NCVkeHUh?=
BV-173 cell NFH5TZhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETXN2NKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh6NUmg{txO M3fxbHNCVkeHUh?=
Becker cell NG\tU|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWTZWXNxUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NUS1JO69VQ>? M4SxfnNCVkeHUh?=
CAL-148 cell MmX3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml36TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMUS4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|UvPjV3NzFOwG0> MWLTRW5ITVJ?
TE-10 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2r2S2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk45PDJ|IN88US=> NYLL[JhMW0GQR1XS
TE-12 cell M3[3WWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV;he4xYUW6qaXLpeIlwdiCxZjDoeY1idiCWRT2xNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMzNjRzMUSg{txO Mm\SV2FPT0WU
TE-8 cell NFXYcJNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUXjUFlYUW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvPjB6OTFOwG0> MkXOV2FPT0WU
TE-9 cell NID1NGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXvJcZV6UW6qaXLpeIlwdiCxZjDoeY1idiCWRT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPjN6MTFOwG0> M2TCfHNCVkeHUh?=
TGW cell NH3MdmZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnLhTY5pcWKrdHnvckBw\iCqdX3hckBVT1diY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz6zOVc4KM7:TR?= NXrubHl1W0GQR1XS
UACC-257 cell MlqzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3\2VWlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdyNkK1JO69VQ>? NUjKc2dEW0GQR1XS
WSU-NHL cell Ml21S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3HKNmlvcGmkaYTpc44hd2ZiaIXtZY4hX1OXLV7IUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI4NjF7MEeg{txO MUfTRW5ITVJ?
no-10 cell M2PZ[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWfJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD62Olg1PiEQvF2= NHizOnlUSU6JRWK=
no-11 cell NUfsO2t2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWroO4ZzUW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjB{NkOg{txO MVnTRW5ITVJ?
CAS-1 cell NGHMR|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mm\RTY5pcWKrdHnvckBw\iCqdX3hckBESVNvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFQ4KM7:TR?= NUXsXHFpW0GQR1XS
CCRF-CEM cell MY\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV3BNHJ6UW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwNkWzPVIh|ryP MorOV2FPT0WU
CMK cell M2TIWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mlr1TY5pcWKrdHnvckBw\iCqdX3hckBEVUtiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkCxN|I{KM7:TR?= MmjHV2FPT0WU
COLO-829 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIm4S2dKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tPFI6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy5{NEKyOkDPxE1? NVz5dFFKW0GQR1XS
COR-L279 cell NWXjeFNxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWrJcohq[mm2aX;uJI9nKGi3bXHuJGNQWi2OMke5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4xPzN6IN88US=> NWXtOY52W0GQR1XS
CP66-MEL cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2j2U2lvcGmkaYTpc44hd2ZiaIXtZY4hS1B4Nj3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Pi53NEm3JO69VQ>? Ml\lV2FPT0WU
CRO-AP2 cell NXPucIx1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1THNGlvcGmkaYTpc44hd2ZiaIXtZY4hS1KRLVHQNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOzZyOEig{txO NUjDR3p4W0GQR1XS
CTV-1 cell NUC3bYdqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4Lmd2lvcGmkaYTpc44hd2ZiaIXtZY4hS1SYLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46OTR3IN88US=> MnHCV2FPT0WU
Calu-6 cell M{Dld2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVH6W4t3UW6qaXLpeIlwdiCxZjDoeY1idiCFYXz1MVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Py53OE[g{txO NIK2UWZUSU6JRWK=
D-247MG cell Mln2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWXBO3RFUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK0O21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54MkixOEDPxE1? MnWyV2FPT0WU
D-263MG cell NIPRUnpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUnJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA5PTB7IN88US=> MWrTRW5ITVJ?
D-336MG cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mk[zTY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Ojh3NDFOwG0> MYfTRW5ITVJ?
D-392MG cell NUn2XINvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXvpR5cyUW6qaXLpeIlwdiCxZjDoeY1idiCGLUO5Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52M{CzPUDPxE1? MnjyV2FPT0WU
D-502MG cell NWjIWGg3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmDwTY5pcWKrdHnvckBw\iCqdX3hckBFNTVyMl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE42OzR7MjFOwG0> MlXzV2FPT0WU
D-542MG cell NIC5S4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIXzWYlKdmirYnn0bY9vKG:oIHj1cYFvKERvNUSyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi5|MUWyJO69VQ>? NIK0cYFUSU6JRWK=
DB cell NF;Hc3hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnvYTY5pcWKrdHnvckBw\iCqdX3hckBFSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR5LkG0NVch|ryP MVXTRW5ITVJ?
DEL cell M2fXVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mo\OTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= NI\aN4hUSU6JRWK=
DMS-114 cell NYjveoI3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEfTdoxKdmirYnn0bY9vKG:oIHj1cYFvKESPUz2xNVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01QS56NE[4JO69VQ>? NXizOIFbW0GQR1XS
DMS-153 cell M2LST2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYDoWGNEUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVU{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwOUmyN{DPxE1? M1P2NHNCVkeHUh?=
DOHH-2 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2C3RWlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4zOjd4NDFOwG0> MXzTRW5ITVJ?
DSH1 cell NGWyPYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGDXcG5KdmirYnn0bY9vKG:oIHj1cYFvKESVSEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlQ{PjJ|IN88US=> NYS1OlFTW0GQR1XS
Daudi cell M{jrR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkG2TY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN NGfYWIRUSU6JRWK=
EC-GI-10 cell MkHsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnLLTY5pcWKrdHnvckBw\iCqdX3hckBGSy2JST2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ1NjJ3OEmg{txO NH7FVpdUSU6JRWK=
ECC4 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUfJcohq[mm2aX;uJI9nKGi3bXHuJGVESzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mj6xPFk3KM7:TR?= NEfMTGVUSU6JRWK=
EM-2 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4fKS2lvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOFU2QTRizszN NHvHbYtUSU6JRWK=
ES1 cell NUTzdohQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWfJcohq[mm2aX;uJI9nKGi3bXHuJGVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSwPFch|ryP NGG5VnZUSU6JRWK=
ES3 cell M1ntOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmfaTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj60O|I6KM7:TR?= MXXTRW5ITVJ?
ES4 cell MmDLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEfncWtKdmirYnn0bY9vKG:oIHj1cYFvKEWVNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO1MlE6PSEQvF2= M4DJUXNCVkeHUh?=
ES6 cell M2fGOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGHvNHhKdmirYnn0bY9vKG:oIHj1cYFvKEWVNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlQ4OzNizszN M4X5e3NCVkeHUh?=
ES7 cell NX:yVYZFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXzJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwMkOxNlQh|ryP M2PnbXNCVkeHUh?=
ES8 cell M3LUbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;z[m1DUW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlgyQTJ2IN88US=> MVzTRW5ITVJ?
EW-18 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJGVYNTF6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOlc2QSEQvF2= NHTpNGFUSU6JRWK=
EW-22 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUnxT4QxUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2yNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4Njd7NEeg{txO MV3TRW5ITVJ?
GCIY cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHfkSYtKdmirYnn0bY9vKG:oIHj1cYFvKEeFSWmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlgxOzh7IN88US=> NYeyUo81W0GQR1XS
GDM-1 cell MnHCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX\ufFhkUW6qaXLpeIlwdiCxZjDoeY1idiCJRF2tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvOzlzOU[g{txO M4\zenNCVkeHUh?=
GI-1 cell NWGzdJJKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4jk[mlvcGmkaYTpc44hd2ZiaIXtZY4hT0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA2OjNizszN NH7ON|RUSU6JRWK=
GI-ME-N cell NVz1OlF{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWDJcohq[mm2aX;uJI9nKGi3bXHuJGdKNU2HLV6gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1QTVzIN88US=> M{e4cXNCVkeHUh?=
GR-ST cell M2H5OGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlT1TY5pcWKrdHnvckBw\iCqdX3hckBIWi2VVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlc6ODJizszN MoD3V2FPT0WU
GT3TKB cell NVryVXVST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGdVO1SNQjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlA{QDlizszN NH\XcmtUSU6JRWK=
HAL-01 cell NFf6TGFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVThVFJ2UW6qaXLpeIlwdiCxZjDoeY1idiCKQVytNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjZ7N{GyJO69VQ>? NWWxS5p1W0GQR1XS
HCC1599 cell MnroS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXvnUnF6UW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OxOVk6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzdwNkCxNUDPxE1? M3[3TnNCVkeHUh?=
HCC2218 cell MlPVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2LHZmlvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkKxPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjN6M{Sg{txO NFn4VIpUSU6JRWK=
HD-MY-Z cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV7YSGlbUW6qaXLpeIlwdiCxZjDoeY1idiCKRD3NXU1bKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwMkG0OkDPxE1? NUnzfWNUW0GQR1XS
HL-60 cell M3fkW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWjLeGZkUW6qaXLpeIlwdiCxZjDoeY1idiCKTD22NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjJzMUSg{txO MoXLV2FPT0WU
HOP-62 cell MoLiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUP3UIFNUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? NHfKN3BUSU6JRWK=
HT cell M1y0c2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlLzTY5pcWKrdHnvckBw\iCqdX3hckBJXCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNESzNlEh|ryP MmLwV2FPT0WU
HT-144 cell NHvkSpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn24TY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlkxPjh4IN88US=> NEXyN4xUSU6JRWK=
HUTU-80 cell NXfiU5VxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF[4O4dKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njd6OUi2JO69VQ>? NEjGXnRUSU6JRWK=
IST-MEL1 cell MlPYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFjWSFVKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3NSWwyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwOUC4OkDPxE1? MlH4V2FPT0WU
IST-SL1 cell MlW1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEj2TGhKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjF5MEe5JO69VQ>? NYfrenpGW0GQR1XS
IST-SL2 cell NVK2PIZOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkDYTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> MXrTRW5ITVJ?
K052 cell NHmxNmlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIPLWmdKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> NX;2VWpVW0GQR1XS
K5 cell Mom1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3XyR2lvcGmkaYTpc44hd2ZiaIXtZY4hUzViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mz61PVE2KM7:TR?= NH3Oe5JUSU6JRWK=
KALS-1 cell NXHtc3hpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoPJTY5pcWKrdHnvckBw\iCqdX3hckBMSUyVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU4{QTZ7IN88US=> NE[0eG9USU6JRWK=
KARPAS-422 cell MkmxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4H4WmlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP M3\XWXNCVkeHUh?=
KARPAS-45 cell NUG3doVqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkXJTY5pcWKrdHnvckBw\iCqdX3hckBMSVKSQWOtOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjFzMkS3JO69VQ>? MW\TRW5ITVJ?
KE-37 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF\1NGdKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU45OzVizszN M{TQNXNCVkeHUh?=
KG-1 cell M2qy[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmrjTY5pcWKrdHnvckBw\iCqdX3hckBMTy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVc2PyEQvF2= MkHwV2FPT0WU
KGN cell NX7PV3B{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3LSW2lvcGmkaYTpc44hd2ZiaIXtZY4hU0eQIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD61Olc1OiEQvF2= NVT6eVVCW0GQR1XS
KM12 cell NXvmT25RT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWLJcohq[mm2aX;uJI9nKGi3bXHuJGtOOTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkWyPVY1KM7:TR?= NIP3V2pUSU6JRWK=
KMOE-2 cell NWXmU25wT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYDiNoN2UW6qaXLpeIlwdiCxZjDoeY1idiCNTV;FMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC52NUS5JO69VQ>? MXXTRW5ITVJ?
KNS-42 cell M2m0cGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVy0UlkzUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjhzOUG1JO69VQ>? M4W4Z3NCVkeHUh?=
KNS-81-FD cell MlHGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{HxdWlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUixMWZFKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzdwNEK2JO69VQ>? MlXsV2FPT0WU
KS-1 cell MnnhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUK2OGRXUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODR4IN88US=> NVK3[ndqW0GQR1XS
KU812 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFHTXldKdmirYnn0bY9vKG:oIHj1cYFvKEuXOEGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvPDh2IN88US=> NVj6cINtW0GQR1XS
L-540 cell NETjSmVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnrOTY5pcWKrdHnvckBw\iCqdX3hckBNNTV2MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKwMlc1PDVizszN MmHpV2FPT0WU
LAMA-84 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;ofGlEUW6qaXLpeIlwdiCxZjDoeY1idiCOQV3BMVg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwNke0NkDPxE1? NHXFXWxUSU6JRWK=
LB1047-RCC cell NFrxT3pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUPJcohq[mm2aX;uJI9nKGi3bXHuJGxDOTB2Nz3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQC5|OEizJO69VQ>? M2n2UnNCVkeHUh?=
LB2241-RCC cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVrJcohq[mm2aX;uJI9nKGi3bXHuJGxDOjJ2MT3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC53NUO2JO69VQ>? NWX3TGpyW0GQR1XS
LB2518-MEL cell NIOyelFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NI[ydJJKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkWxPE1OTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkexOFk3|ryP M3rrbnNCVkeHUh?=
LB831-BLC cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXzJcohq[mm2aX;uJI9nKGi3bXHuJGxDQDNzLVLMR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjF5Mk[g{txO Mon0V2FPT0WU
LB996-RCC cell NInBRXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXjJcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd2M{Gg{txO M1nnTnNCVkeHUh?=
LC4-1 cell NE[0WJZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGxEPC1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{KuPFM1OSEQvF2= NYXFNJo4W0GQR1XS
LOUCY cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkLaTY5pcWKrdHnvckBw\iCqdX3hckBNV1WFWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVUzPzZizszN Mn70V2FPT0WU
LOXIMVI cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3HpUmlvcGmkaYTpc44hd2ZiaIXtZY4hVE:[SV3WTUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjJzMkKg{txO NX76N49NW0GQR1XS
LS-123 cell MmDFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGxUNTF{MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlIzPThizszN Mlv2V2FPT0WU
LU-134-A cell NFnndVZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYfJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|ND3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yPDB4ODFOwG0> NGWyV2pUSU6JRWK=
LU-139 cell Mo\ZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkXMTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk4zOThizszN NF\YN2RUSU6JRWK=
LXF-289 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4DHZmlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjR|NUJOwG0> NYK4Onp7W0GQR1XS
MC116 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2DT[WlvcGmkaYTpc44hd2ZiaIXtZY4hVUNzMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20OU4xQDRzIN88US=> Mk\YV2FPT0WU
MDA-MB-134-VI cell NYP2WplCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUTSS4F{UW6qaXLpeIlwdiCxZjDoeY1idiCPRFGtUWIuOTN2LW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvOjR6NjFOwG0> M{LKVXNCVkeHUh?=
MFH-ino cell NUezUZpPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1W3TGlvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjR|OEOg{txO MXLTRW5ITVJ?
MHH-NB-11 cell MnL0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFftXnNKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3ORk0yOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwME[2PUDPxE1? MXjTRW5ITVJ?
ML-2 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnmTG8zUW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODNyNDFOwG0> MlfxV2FPT0WU
MOLT-13 cell MoG3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1fYbmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvPDN4NUOg{txO MYXTRW5ITVJ?
MOLT-16 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWfQXoJwUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5zMUG2N{DPxE1? NUDMV3ZZW0GQR1XS
MOLT-4 cell NVrobW1NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEHPdHhKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjRzMkSg{txO MXfTRW5ITVJ?
MPP-89 cell NHy0N4ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVPJcohq[mm2aX;uJI9nKGi3bXHuJG1RWC16OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNlU6OjJizszN MULTRW5ITVJ?
MRK-nu-1 cell M3XYdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlKwTY5pcWKrdHnvckBw\iCqdX3hckBOWktvboWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPTd3N{Kg{txO MUPTRW5ITVJ?
MSTO-211H cell NWjVR2FOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlPhTY5pcWKrdHnvckBw\iCqdX3hckBOW1SRLUKxNWgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi56Nkmg{txO NHrHS5JUSU6JRWK=
MV-4-11 cell NVLTZYFNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{fqZ2lvcGmkaYTpc44hd2ZiaIXtZY4hVVZvND2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTN7MUWg{txO NXrwbVE{W0GQR1XS
NALM-6 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mlz6TY5pcWKrdHnvckBw\iCqdX3hckBPSUyPLU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlU3OTB7IN88US=> M4XF[3NCVkeHUh?=
NB1 cell Ml\GS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1\uVWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz64OFM3QSEQvF2= Mn3QV2FPT0WU
NB10 cell NIj3U2dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXTJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkGzPVE2KM7:TR?= NV\UWJRzW0GQR1XS
NB12 cell M2TIcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnvETY5pcWKrdHnvckBw\iCqdX3hckBPSjF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MU[uOVY2PiEQvF2= NX3SW5p1W0GQR1XS
NB13 cell NI\jPXZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmXOTY5pcWKrdHnvckBw\iCqdX3hckBPSjF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6zNVI4QCEQvF2= MlLDV2FPT0WU
NB17 cell M1TFTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkW4NFUyKM7:TR?= NGXacGZUSU6JRWK=
NB6 cell NV7EV2lWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M37EPGlvcGmkaYTpc44hd2ZiaIXtZY4hVkJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD61PVEyPCEQvF2= NYrIbIFyW0GQR1XS
NCCIT cell NIjt[IFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEXPO|hKdmirYnn0bY9vKG:oIHj1cYFvKE6FQ1nUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFEvQDR3MzFOwG0> NFPLc5pUSU6JRWK=
NCI-H1155 cell NEK5[WJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWTJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUG1OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjN2MEig{txO MojiV2FPT0WU
NCI-H1304 cell M2HG[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX3Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO MnL6V2FPT0WU
NCI-H1355 cell NWKyNpNET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX3Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUO1OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTRzMTFOwG0> NF7DeIdUSU6JRWK=
NCI-H1395 cell MlTxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGO1NINKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVM6PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3PVUh|ryP M4DRfHNCVkeHUh?=
NCI-H1417 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4XUUGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFE4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS54N{WyNkDPxE1? NXLLcZBRW0GQR1XS
NCI-H1436 cell MmnLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUPzNpB6UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE1OzZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lki0NVAyKM7:TR?= NHHBblRUSU6JRWK=
NTERA-S-cl-D1 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{CwU2lvcGmkaYTpc44hd2ZiaIXtZY4hVlSHUlGtV{1kdC2GMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlg6OzVizszN NIq5eIJUSU6JRWK=
JiyoyeP-2003 cell NX7hdWhRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoLOTY5pcWKrdHnvckBw\iCqdX3hckBLcXmxeXXQMVIxODNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nj62Nlg1KM7:TR?= MY\TRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
+ Expand
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID