GSK269962A HCl

For research use only.

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

5 publications

GSK269962A HCl Chemical Structure

CAS No. 2095432-71-4

GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

Selleck's GSK269962A HCl has been cited by 5 publications

Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoXkTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG1PFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC56NEe3JO69VQ>? M33tbXNCVkeHUh?=
NCI-H1694 NH3LW49Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{jvXGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlk1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOEe0PUDPxE1? M4fkZXNCVkeHUh?=
NCI-H1963 NIfISFRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn3STY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG5OlMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ5OEO5JO69VQ>? MWrTRW5ITVJ?
NCI-H2081 MmfqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlLFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC54MES0JO69VQ>? NFvH[IFUSU6JRWK=
NCI-H209 NGryWYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVvqTZdOUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIxQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lk[yO|Ih|ryP NWS5NmhkW0GQR1XS
NCI-H2107 NYK4cFJ4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3rTdmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVA4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwNkW2NUDPxE1? MWfTRW5ITVJ?
NCI-H2126 NYn2[Wh6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmHLTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjVyNEK2JO69VQ>? Mk\rV2FPT0WU
NCI-H2171 NHzoSIVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV3NbVFnUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm1PVM4KM7:TR?= NXXtXFVvW0GQR1XS
NCI-H2227 NWi0dnBxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkKyO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvQDh4MU[g{txO MVHTRW5ITVJ?
NCI-H524 NVvkOXE{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnjqTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh5NkOg{txO M3rv[3NCVkeHUh?=
NCI-H526 NX;M[JVjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnSzTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV2M{Gg{txO M2\lTnNCVkeHUh?=
NCI-H720 NG\1SWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2exPWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi3NlAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjR3MU[xJO69VQ>? M{jmcXNCVkeHUh?=
NMC-G1 NGHlWI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUHJcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG1MlA2PzhizszN MoXpV2FPT0WU
NOS-1 cell Mn;TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4jhXmlvcGmkaYTpc44hd2ZiaIXtZY4hVk:VLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlgzOjl2IN88US=> MYfTRW5ITVJ?
OCI-AML2 cell NXvWWZU2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUjJcohq[mm2aX;uJI9nKGi3bXHuJG9EUS2DTVyyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVAvQTR7NjFOwG0> MW\TRW5ITVJ?
OCUB-M cell NWjzdo9pT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWTJcohq[mm2aX;uJI9nKGi3bXHuJG9EXUJvTTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG3MlIxOSEQvF2= NXjHU3dVW0GQR1XS
ONS-76 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYTJcohq[mm2aX;uJI9nKGi3bXHuJG9PWy15NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlkyQTFizszN NWDwNoFNW0GQR1XS
OS-RC-2 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkjPTY5pcWKrdHnvckBw\iCqdX3hckBQWy2UQz2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvOTl3IN88US=> MXHTRW5ITVJ?
OVCAR-4 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWLUV|NNUW6qaXLpeIlwdiCxZjDoeY1idiCRVlPBVk01KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC55MUiwPEDPxE1? MkjvV2FPT0WU
P30-OHK cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFHlVllKdmirYnn0bY9vKG:oIHj1cYFvKFB|MD3PTGsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjZ{OEe3JO69VQ>? MVXTRW5ITVJ?
P30-OHK cell M{W1Umdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2fVe2lvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4xPDl3NDFOwG0> MVTTRW5ITVJ?
PSN1 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4fOc2lvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNlIyOjZizszN MmH5V2FPT0WU
QIMR-WIL cell NYDENms5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYrUUmRRUW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEmwNFQh|ryP MXvTRW5ITVJ?
RCC10RGB cell M3;nfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHj5OXpKdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOUCzOkDPxE1? NYr6d2VGW0GQR1XS
RKO cell NIDZOllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2PMXGlvcGmkaYTpc44hd2ZiaIXtZY4hWkuRIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUCuOVY3OiEQvF2= M3TsUXNCVkeHUh?=
RL95-2 cell M1jJd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml62TY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE43PyEQvF2= MVjTRW5ITVJ?
RPMI-6666 cell MomxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHfKW|FKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtOlY3PiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF6LkWyN|Yh|ryP M1PrVHNCVkeHUh?=
RPMI-8402 cell Mlm4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGO1eGdKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? MVnTRW5ITVJ?
RXF393 cell M4\K[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkW0TY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM6OyEQvF2= NILyXndUSU6JRWK=
Ramos-2G6-4C10 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWHJcohq[mm2aX;uJI9nKGi3bXHuJHJidW:|LULHOk01SzFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6zOVch|ryP NI\KeJZUSU6JRWK=
SCLC-21H cell MnPOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXrJcohq[mm2aX;uJI9nKGi3bXHuJHNEVENvMkHIJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43OTF2OTFOwG0> NUGyb2x1W0GQR1XS
SF126 cell NHvlT5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYO3NWxoUW6qaXLpeIlwdiCxZjDoeY1idiCVRkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh|MkJOwG0> MVnTRW5ITVJ?
SF268 cell M3rl[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYjJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjZ6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6yN|E5OyEQvF2= NI\CVm1USU6JRWK=
SF539 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIHkXZdKdmirYnn0bY9vKG:oIHj1cYFvKFOINUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zQDZ4MTFOwG0> Ml3uV2FPT0WU
SH-4 cell NWX4OFh5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWTJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= NIf5Z4hUSU6JRWK=
SIG-M5 cell MoLJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M13NWGlvcGmkaYTpc44hd2ZiaIXtZY4hW0mJLV21JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvPzJ3OTFOwG0> MlrxV2FPT0WU
SJSA-1 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXjNcGtXUW6qaXLpeIlwdiCxZjDoeY1idiCVSmPBMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB2NUK2JO69VQ>? MYnTRW5ITVJ?
SK-LMS-1 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNUyPUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvPTl4NTFOwG0> MXjTRW5ITVJ?
SK-MM-2 cell M{Ljcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2G3W2lvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTV2tNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjN2MEWg{txO M3naN3NCVkeHUh?=
SK-N-DZ cell NXP5WWpQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFzkPGlKdmirYnn0bY9vKG:oIHj1cYFvKFONLV6tSHoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF06NjR6M{G0JO69VQ>? M{fxdnNCVkeHUh?=
SK-NEP-1 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2LrNGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTlXQMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy53NEW2JO69VQ>? MnHOV2FPT0WU
SK-PN-DW cell MnK4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkfGTY5pcWKrdHnvckBw\iCqdX3hckBUUy2STj3EW{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njl5M{[g{txO NWKwb3BtW0GQR1XS
SNB75 cell NFHIZWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2\FSmlvcGmkaYTpc44hd2ZiaIXtZY4hW06EN{WgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlA4PzN5IN88US=> MVTTRW5ITVJ?
SR cell M3OxbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoPZTY5pcWKrdHnvckBw\iCqdX3hckBUWiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMECwNVM4KM7:TR?= MWHTRW5ITVJ?
SU-DHL-1 cell MmHyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmW1TY5pcWKrdHnvckBw\iCqdX3hckBUXS2GSFytNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd|M{[g{txO NXLvfnlUW0GQR1XS
SW684 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmCxTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= MkW5V2FPT0WU
SW872 cell NH;Q[WVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml3PTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFg3PTZizszN NESxZ5FUSU6JRWK=
SW962 cell M1T1UGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnnyTY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlc2OjFizszN M1HSO3NCVkeHUh?=
697 cell M3\zVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWH2NGdJUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI6QTFizszN MWDTRW5ITVJ?
8-MG-BA cell MkfKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnjrTY5pcWKrdHnvckBw\iCqdX3hckA5NU2JLVLBJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvODd7MzFOwG0> MmHyV2FPT0WU
A101D cell MofzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3P3U2lvcGmkaYTpc44hd2ZiaIXtZY4hSTFyMVSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlg4ODN2IN88US=> M1\qc3NCVkeHUh?=
ACN cell M1ztfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJGFEViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJzLkSzPFch|ryP M{XBZ3NCVkeHUh?=
AM-38 cell NWTGc5dbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVzJcohq[mm2aX;uJI9nKGi3bXHuJGFONTN6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nz6yOlMzPyEQvF2= MWfTRW5ITVJ?
ATN-1 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1vvbWlvcGmkaYTpc44hd2ZiaIXtZY4hSVSQLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOE44PTV3IN88US=> NWDLbGJNW0GQR1XS
BB30-HNC cell NECwbVdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4ruVGlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{NUOyJO69VQ>? NIfGT|FUSU6JRWK=
BB49-HNC cell NYPTWm1xT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWPOR2diUW6qaXLpeIlwdiCxZjDoeY1idiCEQkS5MWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEC3PFkh|ryP NIDnRZhUSU6JRWK=
human BC-1 cell NVrrdVJ1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmHOTY5pcWKrdHnvckBw\iCqdX3hckBDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65O|ExPyEQvF2= NEDBWGxUSU6JRWK=
BE-13 cell MlXZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoHHTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= MofEV2FPT0WU
BL-70 cell MnvnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVHJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTdyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFcxOyEQvF2= NHr4dZRUSU6JRWK=
BV-173 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkDsTY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE45QDV7IN88US=> NXO4VWg{W0GQR1XS
Becker cell M3nXVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWXJcohq[mm2aX;uJI9nKGi3bXHuJGJm[2uncjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlk2PDVizszN NGDrRVFUSU6JRWK=
CAL-148 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mor4TY5pcWKrdHnvckBw\iCqdX3hckBESUxvMUS4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|UvPjV3NzFOwG0> M{jnOnNCVkeHUh?=
TE-10 cell Mor4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NE\MSoxKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDR{MzFOwG0> MYHTRW5ITVJ?
TE-12 cell NIfCdHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlTjTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN NXHVOHF3W0GQR1XS
TE-8 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnzjTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuOlA5QSEQvF2= NW\4ZmE3W0GQR1XS
TE-9 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4rNOGlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO2MlY{QDFizszN NHPJfpVUSU6JRWK=
TGW cell NFjpTmFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn\WTY5pcWKrdHnvckBw\iCqdX3hckBVT1diY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mz6zOVc4KM7:TR?= NV76VG5OW0GQR1XS
UACC-257 cell M2HCe2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYXJcohq[mm2aX;uJI9nKGi3bXHuJHVCS0NvMkW3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44ODZ{NTFOwG0> M2PUNnNCVkeHUh?=
WSU-NHL cell NIDobotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVP1[mxDUW6qaXLpeIlwdiCxZjDoeY1idiCZU2WtUmhNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjdwMUmwO{DPxE1? MWDTRW5ITVJ?
no-10 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX;xWFB3UW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjZ6NE[g{txO NF24RmtUSU6JRWK=
no-11 cell M3rSc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlnZTY5pcWKrdHnvckBw\iCqdX3hckBvdy1zMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlAzPjNizszN MnqyV2FPT0WU
CAS-1 cell NEnafIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVHJRXl4UW6qaXLpeIlwdiCxZjDoeY1idiCFQWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDR5IN88US=> NYr0Z25CW0GQR1XS
CCRF-CEM cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mo[xTY5pcWKrdHnvckBw\iCqdX3hckBES1KILVPFUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPjV|OUKg{txO MonrV2FPT0WU
CMK cell MoTzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHzSdoJKdmirYnn0bY9vKG:oIHj1cYFvKEOPSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFE{OjNizszN MlrqV2FPT0WU
COLO-829 cell MkPlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4TmR2lvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz24Nlkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{NjJ2MkK2JO69VQ>? M1zrTXNCVkeHUh?=
COR-L279 cell NInvNJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M13iOWlvcGmkaYTpc44hd2ZiaIXtZY4hS0:ULVyyO|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjB5M{ig{txO M2i2XHNCVkeHUh?=
CP66-MEL cell M4rORWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnPvTY5pcWKrdHnvckBw\iCqdX3hckBEWDZ4LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjV2OUeg{txO NFXid|hUSU6JRWK=
CRO-AP2 cell NIPKWnFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\hVFgzUW6qaXLpeIlwdiCxZjDoeY1idiCFUl:tRXAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5|NkC4PEDPxE1? MlfLV2FPT0WU
CTV-1 cell M2rxTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUjJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= NUjZSo1lW0GQR1XS
Calu-6 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{Dy[2lvcGmkaYTpc44hd2ZiaIXtZY4hS2GudT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPTh4IN88US=> NYX4bZhxW0GQR1XS
D-247MG cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1fQPWlvcGmkaYTpc44hd2ZiaIXtZY4hTC1{NEfNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjJ6MUSg{txO NYLjco5XW0GQR1XS
D-263MG cell NX\ZUoJoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoLhTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ4M13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDVyOTFOwG0> NVTudpduW0GQR1XS
D-336MG cell M3HB[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUXJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzN4TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlYzQDV2IN88US=> NGnGZpJUSU6JRWK=
D-392MG cell M1Hpbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWfKNYZlUW6qaXLpeIlwdiCxZjDoeY1idiCGLUO5Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52M{CzPUDPxE1? M3\sbXNCVkeHUh?=
D-502MG cell MlTLS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnR[odKdmirYnn0bY9vKG:oIHj1cYFvKERvNUCyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjV|NEmyJO69VQ>? NGLLOWNUSU6JRWK=
D-542MG cell Ml3kS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIHJdI9KdmirYnn0bY9vKG:oIHj1cYFvKERvNUSyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi5|MUWyJO69VQ>? MlvMV2FPT0WU
DB cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn3XTY5pcWKrdHnvckBw\iCqdX3hckBFSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR5LkG0NVch|ryP MkLyV2FPT0WU
DEL cell NFm4UINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkHrTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= MV\TRW5ITVJ?
DMS-114 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYX2d4V1UW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? NXHEeJk{W0GQR1XS
DMS-153 cell NXTQdZBST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2DHR2lvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUG1N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjl7MkOg{txO NIjZW3JUSU6JRWK=
DOHH-2 cell NUnYWItET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3T4TGlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4zOjd4NDFOwG0> MV7TRW5ITVJ?
DSH1 cell NYTLSZF2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVnGZnpyUW6qaXLpeIlwdiCxZjDoeY1idiCGU1ixJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE41OzZ{MzFOwG0> M4TRUXNCVkeHUh?=
Daudi cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4fJdGlvcGmkaYTpc44hd2ZiaIXtZY4hTGG3ZHmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlA6QDB{IN88US=> MVXTRW5ITVJ?
EC-GI-10 cell NHPv[XJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1nxV2lvcGmkaYTpc44hd2ZiaIXtZY4hTUNvR1mtNVAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01PC5{NUi5JO69VQ>? NVPUZo82W0GQR1XS
ECC4 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEnEdlFKdmirYnn0bY9vKG:oIHj1cYFvKEWFQ{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk4yQDl4IN88US=> NVGzRmE4W0GQR1XS
EM-2 cell NWPBXmF2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mlr4TY5pcWKrdHnvckBw\iCqdX3hckBGVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj60OVU6PCEQvF2= M2rJU3NCVkeHUh?=
ES1 cell NWjmfoo2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFvDVlJKdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN NYi4NVZMW0GQR1XS
ES3 cell MoC0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33VbGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuOFczQSEQvF2= M4HzOnNCVkeHUh?=
ES4 cell M{DHeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1vnO2lvcGmkaYTpc44hd2ZiaIXtZY4hTVN2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{WuNVk2KM7:TR?= M1H3O3NCVkeHUh?=
ES6 cell NV72c3BDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{DEcWlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yOFc{OyEQvF2= NXy3Vo1[W0GQR1XS
ES7 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3zjUGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT6yN|EzPCEQvF2= MVnTRW5ITVJ?
ES8 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWj0bY1WUW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlgyQTJ2IN88US=> NVHrVosxW0GQR1XS
EW-18 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEnXRY1KdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPjd3OTFOwG0> MWfTRW5ITVJ?
EW-22 cell NWTqZVdvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWrXZm9xUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2yNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4Njd7NEeg{txO NVn6bZM4W0GQR1XS
GCIY cell NH;VWWtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmDyTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64NFM5QSEQvF2= MlG3V2FPT0WU
GDM-1 cell M{fCNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVrmOIVrUW6qaXLpeIlwdiCxZjDoeY1idiCJRF2tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvOzlzOU[g{txO M37NUXNCVkeHUh?=
GI-1 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWXU[YdtUW6qaXLpeIlwdiCxZjDoeY1idiCJST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODV{MzFOwG0> Mlm3V2FPT0WU
GI-ME-N cell MlPCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXPCd4lnUW6qaXLpeIlwdiCxZjDoeY1idiCJST3NSU1PKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNEm1NUDPxE1? NGq5[YdUSU6JRWK=
GR-ST cell M1LoSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYrJcohq[mm2aX;uJI9nKGi3bXHuJGdTNVOWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuO|kxOiEQvF2= MYnTRW5ITVJ?
GT3TKB cell M1z0NGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml;jTY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlYxOzh7IN88US=> M3TtdXNCVkeHUh?=
HAL-01 cell NVL2cZFsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{LtXGlvcGmkaYTpc44hd2ZiaIXtZY4hUEGOLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok43QTdzMjFOwG0> M1eyb3NCVkeHUh?=
HCC1599 cell NUHabpZ2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml7ZTY5pcWKrdHnvckBw\iCqdX3hckBJS0NzNUm5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|cvPjBzMTFOwG0> MY\TRW5ITVJ?
HCC2218 cell Mm[0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX\MdJVkUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OyNlE5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwM{izOEDPxE1? MkXSV2FPT0WU
HD-MY-Z cell M1LIVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXzJcohq[mm2aX;uJI9nKGi3bXHuJGhFNU2\LWqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOU4zOTR4IN88US=> NWDZeWtZW0GQR1XS
HL-60 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoTDTY5pcWKrdHnvckBw\iCqdX3hckBJVC14MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlIyOTRizszN MlTvV2FPT0WU
HOP-62 cell M{Dmc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVjS[Y97UW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? NWP2VlVnW0GQR1XS
HT cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWnJcohq[mm2aX;uJI9nKGi3bXHuJGhVKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC52NEOyNUDPxE1? NWK1OHNYW0GQR1XS
HT-144 cell MkDPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1PwVGlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE46ODZ6NjFOwG0> NWnzU|RmW0GQR1XS
HUTU-80 cell NHq4Z2lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHfzfVZKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njd6OUi2JO69VQ>? NHi2SlRUSU6JRWK=
IST-MEL1 cell NFHyUIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUHmdYZJUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkmwPFYh|ryP NGXjdINUSU6JRWK=
IST-SL1 cell Moj0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmrITY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4yPzB5OTFOwG0> MmniV2FPT0WU
IST-SL2 cell MmHVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYDJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI3PjB6IN88US=> NUD5XZR4W0GQR1XS
K052 cell M1H0VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIjqW4xKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> NYLDVFV5W0GQR1XS
K5 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYrpT|g3UW6qaXLpeIlwdiCxZjDoeY1idiCNNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOzMlU6OTVizszN M{\4[XNCVkeHUh?=
KALS-1 cell NFf5eXJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYD2TlNjUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQS5|OU[5JO69VQ>? NHzXe3lUSU6JRWK=
KARPAS-422 cell Ml:zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2rrdWlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP NE\qRoJUSU6JRWK=
KARPAS-45 cell M4faU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mk\6TY5pcWKrdHnvckBw\iCqdX3hckBMSVKSQWOtOFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjFzMkS3JO69VQ>? MUTTRW5ITVJ?
KE-37 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHzveXZKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU45OzVizszN NVW2XnkxW0GQR1XS
KG-1 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIOyPXpKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PzV5IN88US=> MWjTRW5ITVJ?
KGN cell MmGzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVfOdpBJUW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PzR{IN88US=> MVfTRW5ITVJ?
KM12 cell MoL6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlPHTY5pcWKrdHnvckBw\iCqdX3hckBMVTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61Nlk3PCEQvF2= NX3oVldmW0GQR1XS
KMOE-2 cell M{PE[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHnRR3FKdmirYnn0bY9vKG:oIHj1cYFvKEuPT1WtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjR3NEmg{txO NXPhXFF[W0GQR1XS
KNS-42 cell NVzVdJBCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfCVIxvUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjhzOUG1JO69VQ>? M2fTR3NCVkeHUh?=
KNS-81-FD cell MlTqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVjJcohq[mm2aX;uJI9nKGi3bXHuJGtPWy16MT3GSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM4NjR{NjFOwG0> MkLKV2FPT0WU
KS-1 cell M2LqPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mo\UTY5pcWKrdHnvckBw\iCqdX3hckBMWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFQ3KM7:TR?= NF;xRZhUSU6JRWK=
KU812 cell NXvqVmN4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnfYTY5pcWKrdHnvckBw\iCqdX3hckBMXThzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlQ5PCEQvF2= MmrkV2FPT0WU
L-540 cell MmO4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGKyO3NKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR2NTFOwG0> MYHTRW5ITVJ?
LAMA-84 cell M4nabWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{PEXGlvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjZ5NEKg{txO M171OXNCVkeHUh?=
LB1047-RCC cell NYHoN4ZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWnVZYE2UW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkiuN|g5OyEQvF2= MlS3V2FPT0WU
LB2241-RCC cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn7PTY5pcWKrdHnvckBw\iCqdX3hckBNSjJ{NEGtVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTBwNUWzOkDPxE1? MV;TRW5ITVJ?
LB2518-MEL cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlHHTY5pcWKrdHnvckBw\iCqdX3hckBNSjJ3MUitUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS55MUS5Ou69VQ>? MYTTRW5ITVJ?
LB831-BLC cell NF3SXZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1\Rc2lvcGmkaYTpc44hd2ZiaIXtZY4hVEJ6M{GtRmxEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTFwMUeyOkDPxE1? MnzxV2FPT0WU
LB996-RCC cell NFvzdHdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWHUd3VuUW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj63OFMyKM7:TR?= NGjibG5USU6JRWK=
LC4-1 cell NH31WIhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2rvZ2lvcGmkaYTpc44hd2ZiaIXtZY4hVEN2LUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk45OzRzIN88US=> M1u3fnNCVkeHUh?=
LOUCY cell NYPHeXNIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlPmTY5pcWKrdHnvckBw\iCqdX3hckBNV1WFWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVUzPzZizszN NWjKZYZqW0GQR1XS
LOXIMVI cell M4TuOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVPJcohq[mm2aX;uJI9nKGi3bXHuJGxQYEmPVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE4zOTJ{IN88US=> NFL3PHdUSU6JRWK=
LS-123 cell M1;1[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NETXb2JKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUGyN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjJ{NUig{txO NWLsXIVOW0GQR1XS
LU-134-A cell MoHxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIXFbVhKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzOE1CKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py5zNEC2PEDPxE1? NVXYdJBNW0GQR1XS
LU-139 cell M1XLT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mm\4TY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk4zOThizszN MUfTRW5ITVJ?
LXF-289 cell M2DXWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIPpeFlKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy52M{Wx{txO MmXOV2FPT0WU
MC116 cell M4DJfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIPh[HFKdmirYnn0bY9vKG:oIHj1cYFvKE2FMUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFUvODh2MTFOwG0> M3e4XnNCVkeHUh?=
MDA-MB-134-VI cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M37rfGlvcGmkaYTpc44hd2ZiaIXtZY4hVUSDLV3CMVE{PC2YSTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlI1QDZizszN MlHLV2FPT0WU
MFH-ino cell M{XVV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{TjTWlvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjR|OEOg{txO M{TVV3NCVkeHUh?=
MHH-NB-11 cell NWmzNI5xT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NInEXpdKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3ORk0yOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwME[2PUDPxE1? Mn[5V2FPT0WU
ML-2 cell M2TINmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVLkSHJSUW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODNyNDFOwG0> MnnhV2FPT0WU
MOLT-13 cell MmXXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1vQTmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvPDN4NUOg{txO NYXzTIRbW0GQR1XS
MOLT-16 cell NFWzS|NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\CT5ZQUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5zMUG2N{DPxE1? M3PPenNCVkeHUh?=
MOLT-4 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVzJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0MlQyOjRizszN NUHu[HVUW0GQR1XS
MPP-89 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmK3TY5pcWKrdHnvckBw\iCqdX3hckBOWFBvOEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI2QTJ{IN88US=> MXrTRW5ITVJ?
MRK-nu-1 cell NUS5Z2NnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7VUoFKdmirYnn0bY9vKG:oIHj1cYFvKE2USz3ueU0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53N{W3NkDPxE1? NYnnV2VPW0GQR1XS
MSTO-211H cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYrJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> Mli1V2FPT0WU
MV-4-11 cell MnvHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEnS[|VKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF|OUG1JO69VQ>? NX7Fd|I2W0GQR1XS
NALM-6 cell Mmm4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWXJcohq[mm2aX;uJI9nKGi3bXHuJG5CVE1vNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOVYyODlizszN M1XQNnNCVkeHUh?=
NB1 cell NVTYW2p3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlvYTY5pcWKrdHnvckBw\iCqdX3hckBPSjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lki0N|Y6KM7:TR?= M3vrOHNCVkeHUh?=
NB10 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MojpTY5pcWKrdHnvckBw\iCqdX3hckBPSjFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xN|kyPSEQvF2= MWPTRW5ITVJ?
NB12 cell NVfx[FhVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4nmW2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG2MlU3PTZizszN MWnTRW5ITVJ?
NB13 cell MlzwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGnmSYhKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlMyOjd6IN88US=> MXjTRW5ITVJ?
NB17 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkPNTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= MmnCV2FPT0WU
NB6 cell NV3RSFlVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHvoe2JKdmirYnn0bY9vKG:oIHj1cYFvKE6ENjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVkyOTRizszN MX7TRW5ITVJ?
NCCIT cell M2PpNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\hWmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOFSWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU45PDV|IN88US=> Mn3xV2FPT0WU
NCI-H1155 cell M4P1fGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{nJR2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixNVU2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTRwM{SwPEDPxE1? NIPw[2VUSU6JRWK=
NCI-H1304 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWDJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO NEPCfG9USU6JRWK=
NCI-H1355 cell NEDBb5VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4XrOmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC57NEGxJO69VQ>? MkPRV2FPT0WU
NCI-H1395 cell M{S1N2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1TkR2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|k2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwOEe5OUDPxE1? M{LYWXNCVkeHUh?=
NCI-H1417 cell NYDqc3RtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn7NTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG0NVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02NjZ5NUKyJO69VQ>? MXvTRW5ITVJ?
NCI-H1436 cell NXT5UFVkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSzOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvQDRzMEGg{txO MmH0V2FPT0WU
NTERA-S-cl-D1 cell M1rnUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGrRepVKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk45QTN3IN88US=> MYDTRW5ITVJ?
JiyoyeP-2003 cell NHLN[lFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUnIO4d7UW6qaXLpeIlwdiCxZjDoeY1idiCMaYnvfYVRNTJyMEOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43Ojh2IN88US=> MVvTRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
- Collapse
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: female Wistar rats
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Water Insoluble
Ethanol '6 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 2095432-71-4
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962
Smiles CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6.Cl

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID