GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NUi1bHhGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2DrNWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOVgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOES3O{DPxE1? MVLTRW5ITVJ?
NCI-H1694 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTsZ|hKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY6PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lki3OFkh|ryP NVn2[2dXW0GQR1XS
NCI-H1963 NVfBNWdbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoCyTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG5OlMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ5OEO5JO69VQ>? NVvDTXBoW0GQR1XS
NCI-H2081 M{nmbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXQTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC54MES0JO69VQ>? NYOzSYdnW0GQR1XS
NCI-H209 MkX1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGHGU|JKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlA6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwNkK3NkDPxE1? NF\mbYtUSU6JRWK=
NCI-H2107 M4LWS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2rwO2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVA4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwNkW2NUDPxE1? M{PHcXNCVkeHUh?=
NCI-H2126 NUnB[og1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkDxTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjVyNEK2JO69VQ>? MVvTRW5ITVJ?
NCI-H2171 NVfTZYsyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGHlSGdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlE4OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwOUW5N|ch|ryP Ml71V2FPT0WU
NCI-H2227 MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGW2RZdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlIzPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwOEi2NVYh|ryP MUPTRW5ITVJ?
NCI-H524 NIH5TlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNUK0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDd4MzFOwG0> M1f0WnNCVkeHUh?=
NCI-H526 M{Tod2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KNUK2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvPTR|MTFOwG0> NXTOSFdGW0GQR1XS
NCI-H720 NYHSfJE3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDs[29PUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFczOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwNEWxOlEh|ryP M{nmSXNCVkeHUh?=
NMC-G1 NE\GelRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVjJcohq[mm2aX;uJI9nKGi3bXHuJG5OSy2JMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG1MlA2PzhizszN NEfYVmtUSU6JRWK=
NOS-1 cell NU\0eY5YT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFH3RodKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU45OjJ7NDFOwG0> MnrMV2FPT0WU
OCI-AML2 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3X5U2lvcGmkaYTpc44hd2ZiaIXtZY4hV0OLLVHNUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC57NEm2JO69VQ>? NIGwVlRUSU6JRWK=
OCUB-M cell MmXhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoDYTY5pcWKrdHnvckBw\iCqdX3hckBQS1WELV2gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{4zODFizszN NXm1TWE6W0GQR1XS
ONS-76 cell NIjTZ5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG9PWy15NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlkyQTFizszN NYq0XXNKW0GQR1XS
OS-RC-2 cell NUjUTnpCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmC2TY5pcWKrdHnvckBw\iCqdX3hckBQWy2UQz2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvOTl3IN88US=> Mn33V2FPT0WU
OVCAR-4 cell Mn3tS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVfJcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlcyQDB6IN88US=> NXK4WIZDW0GQR1XS
P30-OHK cell NEnKNllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MonXTY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43Ojh5NzFOwG0> Mn\pV2FPT0WU
P30-OHK cell NXjud4N6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI\Dbm1KdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvODR7NUSg{txO MlywV2FPT0WU
PSN1 cell NEmwdnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkL0TY5pcWKrdHnvckBw\iCqdX3hckBRW05zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6yNlEzPiEQvF2= NGnMO25USU6JRWK=
QIMR-WIL cell M4LMcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXZTY5pcWKrdHnvckBw\iCqdX3hckBSUU2ULWfJUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPDlyMESg{txO MmnhV2FPT0WU
RCC10RGB cell NH;iOJJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkHyTY5pcWKrdHnvckBw\iCqdX3hckBTS0NzMGLHRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjlyM{[g{txO NGX2ZpVUSU6JRWK=
RKO cell MlH1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml\GTY5pcWKrdHnvckBw\iCqdX3hckBTU09iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OlYzKM7:TR?= MYnTRW5ITVJ?
RL95-2 cell M3zLOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1fnSmlvcGmkaYTpc44hd2ZiaIXtZY4hWkx7NT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVAvPjdizszN NX;1ZXFyW0GQR1XS
RPMI-6666 cell MojhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3HFWmlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? NVGxOWdMW0GQR1XS
RPMI-8402 cell NInOZYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGftSlRKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? NXjvNZF6W0GQR1XS
RXF393 cell M{nSNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVTJcohq[mm2aX;uJI9nKGi3bXHuJHJZTjN7MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|k{KM7:TR?= NWrvRoxpW0GQR1XS
Ramos-2G6-4C10 cell NYnm[Gd2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUPJcohq[mm2aX;uJI9nKGi3bXHuJHJidW:|LULHOk01SzFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6zOVch|ryP Mm[2V2FPT0WU
SCLC-21H cell NHfmWXRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoXHTY5pcWKrdHnvckBw\iCqdX3hckBUS0yFLUKxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjFzNEmg{txO MnryV2FPT0WU
SF126 cell MmXRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4DLOmlvcGmkaYTpc44hd2ZiaIXtZY4hW0ZzMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU45OzJzzszN NX;ZOXlIW0GQR1XS
SF268 cell M{fPTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjZ6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6yN|E5OyEQvF2= MY\TRW5ITVJ?
SF539 cell MmL4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH32c2dKdmirYnn0bY9vKG:oIHj1cYFvKFOINUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zQDZ4MTFOwG0> NV23VYtPW0GQR1XS
SH-4 cell MmXuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGnRWW9KdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlc2PTB6IN88US=> MlO3V2FPT0WU
SIG-M5 cell M1e0SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWnJcohq[mm2aX;uJI9nKGi3bXHuJHNKTy2PNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGxMlczPTlizszN NYm3dXNXW0GQR1XS
SJSA-1 cell NVfKVIZjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXnJcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFQ2OjZizszN MYfTRW5ITVJ?
SK-LMS-1 cell M2Dzfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLURXZKdmirYnn0bY9vKG:oIHj1cYFvKFONLVzNV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwNUm2OUDPxE1? MUXTRW5ITVJ?
SK-MM-2 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWXJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2PLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk4{PDB3IN88US=> MYLTRW5ITVJ?
SK-N-DZ cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4XvcmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTj3EXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPDh|MUSg{txO NY[xVXFYW0GQR1XS
SK-NEP-1 cell NH\TR3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnPJTY5pcWKrdHnvckBw\iCqdX3hckBUUy2QRWCtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjV2NU[g{txO MkTuV2FPT0WU
SK-PN-DW cell NVXCeGl2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NI[2b41KdmirYnn0bY9vKG:oIHj1cYFvKFONLWDOMWRYKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOUezOkDPxE1? NVXk[Y06W0GQR1XS
SNB75 cell MlXNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnT4TY5pcWKrdHnvckBw\iCqdX3hckBUVkJ5NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuNFc4OzdizszN Mk\iV2FPT0WU
SR cell NWfXOXZXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWLhcYo1UW6qaXLpeIlwdiCxZjDoeY1idiCVUjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAxOTN5IN88US=> MVLTRW5ITVJ?
SU-DHL-1 cell NGXsV2dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHvsTZBKdmirYnn0bY9vKG:oIHj1cYFvKFOXLVTIUE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwN{OzOkDPxE1? NXjiNYlMW0GQR1XS
SW684 cell MkS3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmLITY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= NVnIbI1jW0GQR1XS
SW872 cell NI\GRYhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVPJWVg{UW6qaXLpeIlwdiCxZjDoeY1idiCVV{i3NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDh4NU[g{txO NV\wT2cyW0GQR1XS
SW962 cell NWHOVZg3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHTzXWRKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPzV{MTFOwG0> MVfTRW5ITVJ?
697 cell NVv5NI1OT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUGzdY1mUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI6QTFizszN NXf2VVR4W0GQR1XS
8-MG-BA cell MnPYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlHDTY5pcWKrdHnvckBw\iCqdX3hckA5NU2JLVLBJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvODd7MzFOwG0> Mom4V2FPT0WU
A101D cell NUXSVItZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVPJcohq[mm2aX;uJI9nKGi3bXHuJGEyODGGIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64O|A{PCEQvF2= M4SyOnNCVkeHUh?=
ACN cell M3\sfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHT2WI5KdmirYnn0bY9vKG:oIHj1cYFvKEGFTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKxMlQ{QDdizszN MnrpV2FPT0WU
AM-38 cell NWL2OGxNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGja[HlKdmirYnn0bY9vKG:oIHj1cYFvKEGPLUO4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4zPjN{NzFOwG0> MlLIV2FPT0WU
ATN-1 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHT0R5FKdmirYnn0bY9vKG:oIHj1cYFvKEGWTj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlQvPzV3NTFOwG0> M1HlcnNCVkeHUh?=
BB30-HNC cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFHJRmRKdmirYnn0bY9vKG:oIHj1cYFvKEKEM{CtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwMkWzNkDPxE1? MXLTRW5ITVJ?
BB49-HNC cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU[yR21FUW6qaXLpeIlwdiCxZjDoeY1idiCEQkS5MWhPSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEC3PFkh|ryP NU\BXppLW0GQR1XS
human BC-1 cell M{GwWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXHZXIZoUW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46PzFyNzFOwG0> M3vCPXNCVkeHUh?=
BE-13 cell NEPmVpJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYP1TFBuUW6qaXLpeIlwdiCxZjDoeY1idiCERT2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOTRyOEJOwG0> NUHwNZVsW0GQR1XS
BL-70 cell M4m3R2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlnnTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOFA4ODNizszN NV72emJqW0GQR1XS
BV-173 cell Mlf5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3PGfGlvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvQDh3OTFOwG0> NU\6RlAxW0GQR1XS
Becker cell M3f0dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVvRWnRHUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NUS1JO69VQ>? MnTxV2FPT0WU
CAL-148 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1L0fGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO M2fUUnNCVkeHUh?=
TE-10 cell MkXSS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEjN[|ZKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDR{MzFOwG0> MXHTRW5ITVJ?
TE-12 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlH6TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN NF3sUHJUSU6JRWK=
TE-8 cell NVfyVWF7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT62NFg6KM7:TR?= M3jY[nNCVkeHUh?=
TE-9 cell NITr[Y1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEDHXGpKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43OzhzIN88US=> MXPTRW5ITVJ?
TGW cell NXTZfGZ[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\CU5VmUW6qaXLpeIlwdiCxZjDoeY1idiCWR2egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4{PTd5IN88US=> Mo[yV2FPT0WU
UACC-257 cell MkLFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkT4TY5pcWKrdHnvckBw\iCqdX3hckBWSUOFLUK1O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPzB4MkWg{txO MYPTRW5ITVJ?
WSU-NHL cell NIq3S41Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWfJcohq[mm2aX;uJI9nKGi3bXHuJHdUXS2QSFygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yO{4yQTB5IN88US=> NFjMXVBUSU6JRWK=
no-10 cell NYTUOYxNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD62Olg1PiEQvF2= MW\TRW5ITVJ?
no-11 cell MkHTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWPJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuNFI3OyEQvF2= MWfTRW5ITVJ?
CAS-1 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYDoNo5yUW6qaXLpeIlwdiCxZjDoeY1idiCFQWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDR5IN88US=> MWHTRW5ITVJ?
CCRF-CEM cell MojJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUmyWIR[UW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwNkWzPVIh|ryP MX3TRW5ITVJ?
CMK cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWrPUJNDUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAyOzJ|IN88US=> Mk\vV2FPT0WU
COLO-829 cell NHnSTXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnLRTY5pcWKrdHnvckBw\iCqdX3hckBEV0yRLUiyPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOjR{Mk[g{txO M13zT3NCVkeHUh?=
COR-L279 cell NWTqOVk1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7lTYxKdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5yN{O4JO69VQ>? MWrTRW5ITVJ?
CP66-MEL cell Mn34S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mn72TY5pcWKrdHnvckBw\iCqdX3hckBEWDZ4LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjV2OUeg{txO MmXUV2FPT0WU
CRO-AP2 cell NX3RW|JIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoXmTY5pcWKrdHnvckBw\iCqdX3hckBEWk9vQWCyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{PjB6ODFOwG0> NUHVT2JkW0GQR1XS
CTV-1 cell NHy5bWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXvJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= Mn7DV2FPT0WU
Calu-6 cell NHXNTI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFzTUHNKdmirYnn0bY9vKG:oIHj1cYFvKEOjbIWtOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjV6NjFOwG0> MUPTRW5ITVJ?
D-247MG cell NYnvWpA3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWPxbGVxUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK0O21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54MkixOEDPxE1? M2KzTnNCVkeHUh?=
D-263MG cell M{TVN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUC4bIZPUW6qaXLpeIlwdiCxZjDoeY1idiCGLUK2N21IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yOEWwPUDPxE1? MX\TRW5ITVJ?
D-336MG cell Mnn5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWracZhvUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54Mki1OEDPxE1? NYDyW3plW0GQR1XS
D-392MG cell NGTUd4VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVLBeGlIUW6qaXLpeIlwdiCxZjDoeY1idiCGLUO5Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52M{CzPUDPxE1? NV;GNJQyW0GQR1XS
D-502MG cell NY\pVGx1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWnJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTB{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlU{PDl{IN88US=> Mly1V2FPT0WU
D-542MG cell M3vN[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTR{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk4{OTV{IN88US=> NE[ySlZUSU6JRWK=
DB cell NWP2c5F6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFzVTllKdmirYnn0bY9vKG:oIHj1cYFvKESEIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuNVQyPyEQvF2= NVvXOHdXW0GQR1XS
DEL cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJGRGVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwMEG4PVgh|ryP NID4VW5USU6JRWK=
DMS-114 cell NE\mW2VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfl[YJTUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? M2DqdHNCVkeHUh?=
DMS-153 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1PG[GlvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUG1N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjl7MkOg{txO MkDJV2FPT0WU
DOHH-2 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVfJcohq[mm2aX;uJI9nKGi3bXHuJGRQUEhvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuNlI4PjRizszN M{\afnNCVkeHUh?=
DSH1 cell M1G2eGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1TCUmlvcGmkaYTpc44hd2ZiaIXtZY4hTFOKMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuOFM3OjNizszN MVnTRW5ITVJ?
Daudi cell NX;5UXkyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml;xTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN NIfjepJUSU6JRWK=
EC-GI-10 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFSwUpBKdmirYnn0bY9vKG:oIHj1cYFvKEWFLVfJMVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDRwMkW4PUDPxE1? NYGzbIJXW0GQR1XS
ECC4 cell NXTBUo0xT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M37UcGlvcGmkaYTpc44hd2ZiaIXtZY4hTUOFNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlE5QTZizszN MX7TRW5ITVJ?
EM-2 cell NYL4VGhKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4rKVmlvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOFU2QTRizszN NFLHWIRUSU6JRWK=
ES1 cell MoTaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFvWOlVKdmirYnn0bY9vKG:oIHj1cYFvKEWVMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOVQxQDdizszN M{\tcHNCVkeHUh?=
ES3 cell NYe4cphWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3TGVGlvcGmkaYTpc44hd2ZiaIXtZY4hTVN|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuOFczQSEQvF2= NVrtZlAyW0GQR1XS
ES4 cell M1zJW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUHqN3J7UW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU4yQTVizszN NIe4bZpUSU6JRWK=
ES6 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVTJcohq[mm2aX;uJI9nKGi3bXHuJGVUPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMkS3N|Mh|ryP NIe1[HpUSU6JRWK=
ES7 cell M3fFO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVi5VoE1UW6qaXLpeIlwdiCxZjDoeY1idiCHU{egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlI{OTJ2IN88US=> M3G3cXNCVkeHUh?=
ES8 cell NHTVZnlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mlv6TY5pcWKrdHnvckBw\iCqdX3hckBGWzhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkixPVI1KM7:TR?= M{nMPHNCVkeHUh?=
EW-18 cell NVWzdYw2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1q1SWlvcGmkaYTpc44hd2ZiaIXtZY4hTVdvMUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43PzV7IN88US=> Ml;EV2FPT0WU
EW-22 cell NFLXRZFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVq0VXgzUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2yNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4Njd7NEeg{txO MkHNV2FPT0WU
GCIY cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUXJcohq[mm2aX;uJI9nKGi3bXHuJGdEUVliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD17LkiwN|g6KM7:TR?= MmPsV2FPT0WU
GDM-1 cell NUPCeG5xT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= MnrFV2FPT0WU
GI-1 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\D[GlvcGmkaYTpc44hd2ZiaIXtZY4hT0lvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA2OjNizszN MVPTRW5ITVJ?
GI-ME-N cell MkjNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF3nWmpKdmirYnn0bY9vKG:oIHj1cYFvKEeLLV3FMW4h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB2OUWxJO69VQ>? MVfTRW5ITVJ?
GR-ST cell NFfjd|hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3n2V2lvcGmkaYTpc44hd2ZiaIXtZY4hT1JvU2SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{44QTB{IN88US=> M2PHSHNCVkeHUh?=
GT3TKB cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mkf6TY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlYxOzh7IN88US=> MV;TRW5ITVJ?
HAL-01 cell M2Lxb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVu0OHpzUW6qaXLpeIlwdiCxZjDoeY1idiCKQVytNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjZ7N{GyJO69VQ>? MWDTRW5ITVJ?
HCC1599 cell NYWxNWl3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH\qXopKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py54MEGxJO69VQ>? MYjTRW5ITVJ?
HCC2218 cell MnPKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1vlTGlvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMkKxPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjN6M{Sg{txO Mn3zV2FPT0WU
HD-MY-Z cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXu4e3I{UW6qaXLpeIlwdiCxZjDoeY1idiCKRD3NXU1bKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwMkG0OkDPxE1? NVHBRZdQW0GQR1XS
HL-60 cell NHHQ[FBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2jFcGlvcGmkaYTpc44hd2ZiaIXtZY4hUExvNkCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk4zOTF2IN88US=> NGmxZoxUSU6JRWK=
HOP-62 cell MmTzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoXBTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PTJ5IN88US=> M2jtenNCVkeHUh?=
HT cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml7yTY5pcWKrdHnvckBw\iCqdX3hckBJXCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNESzNlEh|ryP MWrTRW5ITVJ?
HT-144 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUnZZY83UW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjlyNki2JO69VQ>? NXjLeJN5W0GQR1XS
HUTU-80 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIezOJZKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njd6OUi2JO69VQ>? NYj6SlI{W0GQR1XS
IST-MEL1 cell MmrwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1zxVGlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi57MEi2JO69VQ>? MVzTRW5ITVJ?
IST-SL1 cell MlTyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1TsWGlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLWPMNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOTdyN{mg{txO MXTTRW5ITVJ?
IST-SL2 cell NFfuW|ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVfJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI3PjB6IN88US=> M{\KbnNCVkeHUh?=
K052 cell NYG3OotST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGsxPTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke1N|AyKM7:TR?= M1zQSHNCVkeHUh?=
K5 cell M2XTb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXXXNFBQUW6qaXLpeIlwdiCxZjDoeY1idiCNNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOzMlU6OTVizszN NYnDdlJrW0GQR1XS
KALS-1 cell NVWxc5hST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4XyR2lvcGmkaYTpc44hd2ZiaIXtZY4hU0GOUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvOzl4OTFOwG0> M1XGNnNCVkeHUh?=
KARPAS-422 cell MnT0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{TrWGlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP M4X4WnNCVkeHUh?=
KARPAS-45 cell M4rSNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUO0cVdtUW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkGxNlQ4KM7:TR?= MXPTRW5ITVJ?
KE-37 cell M37hSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWr0XWx7UW6qaXLpeIlwdiCxZjDoeY1idiCNRT2zO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvQDN3IN88US=> M3rNbnNCVkeHUh?=
KG-1 cell M1nlbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYPpUoR2UW6qaXLpeIlwdiCxZjDoeY1idiCNRz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvQTd3NzFOwG0> NGLyPGRUSU6JRWK=
KGN cell M1PpWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFLXU2FKdmirYnn0bY9vKG:oIHj1cYFvKEuJTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVY4PDJizszN MUPTRW5ITVJ?
KM12 cell M{POSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXjJcohq[mm2aX;uJI9nKGi3bXHuJGtOOTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkWyPVY1KM7:TR?= NFPaVY5USU6JRWK=
KMOE-2 cell NWmxSFF6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoTnTY5pcWKrdHnvckBw\iCqdX3hckBMVU:HLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE41PTR7IN88US=> NEW3Z41USU6JRWK=
KNS-42 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnkR4xRUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjhzOUG1JO69VQ>? MlrhV2FPT0WU
KNS-81-FD cell MkXUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3uwcWlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUixMWZFKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzdwNEK2JO69VQ>? NEPxW4tUSU6JRWK=
KS-1 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlzKTY5pcWKrdHnvckBw\iCqdX3hckBMWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFQ3KM7:TR?= M3rJcHNCVkeHUh?=
KU812 cell NFHYVYNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXv2WVEyUW6qaXLpeIlwdiCxZjDoeY1idiCNVUixNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjR6NDFOwG0> M13Z[nNCVkeHUh?=
L-540 cell MlfyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnnDTY5pcWKrdHnvckBw\iCqdX3hckBNNTV2MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKwMlc1PDVizszN MVTTRW5ITVJ?
LAMA-84 cell MnLVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml\HTY5pcWKrdHnvckBw\iCqdX3hckBNSU2DLUi0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPjd2MjFOwG0> M1[xVnNCVkeHUh?=
LB1047-RCC cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4r0eWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ6LkO4PFMh|ryP MkHCV2FPT0WU
LB2241-RCC cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEXkTllKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkK0NU1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OVM3KM7:TR?= NHjSdm5USU6JRWK=
LB2518-MEL cell NGO0emVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGxDOjVzOD3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjdzNEm2{txO M4DuWnNCVkeHUh?=
LB831-BLC cell NULORoVIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3vBZWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ6M{GtRmxEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTFwMUeyOkDPxE1? M{HBSnNCVkeHUh?=
LB996-RCC cell M2LTS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHrzbVdKdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lke0N|Eh|ryP MoTHV2FPT0WU
LC4-1 cell NWDZR5ZZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmHlTY5pcWKrdHnvckBw\iCqdX3hckBNSzRvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlg{PDFizszN M2m4VHNCVkeHUh?=
LOUCY cell M3rVVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1;xWWlvcGmkaYTpc44hd2ZiaIXtZY4hVE:XQ2mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlE2Ojd4IN88US=> Mn;SV2FPT0WU
LOXIMVI cell NWi1NZBMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnvsTY5pcWKrdHnvckBw\iCqdX3hckBNV1iLTW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvOjF{MjFOwG0> M{PkO3NCVkeHUh?=
LS-123 cell NUHHS4FoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFHHTlFKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUGyN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjJ{NUig{txO NF7NbFFUSU6JRWK=
LU-134-A cell MmXPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUPJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|ND3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yPDB4ODFOwG0> MnH6V2FPT0WU
LU-139 cell M4TvWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkT3TY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk4zOThizszN MnLWV2FPT0WU
LXF-289 cell MmjqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mm\FTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPDN3Md88US=> NGfzWWxUSU6JRWK=
MC116 cell Mn;PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml;mTY5pcWKrdHnvckBw\iCqdX3hckBOSzFzNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS1MlA5PDFizszN NG\kSWVUSU6JRWK=
MDA-MB-134-VI cell NEX6O3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUnJcohq[mm2aX;uJI9nKGi3bXHuJG1FSS2PQj2xN|QuXkliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|OT6yOFg3KM7:TR?= NHfm[nFUSU6JRWK=
MFH-ino cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIL3coJKdmirYnn0bY9vKG:oIHj1cYFvKE2ISD3pco8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ2M{izJO69VQ>? MUXTRW5ITVJ?
MHH-NB-11 cell M1PuVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXPJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODZ4OTFOwG0> M3[zV3NCVkeHUh?=
ML-2 cell NU[zdItIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXnCfFlMUW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODNyNDFOwG0> NHrPbZlUSU6JRWK=
MOLT-13 cell MkXyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXLJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlQ{PjV|IN88US=> MoD6V2FPT0WU
MOLT-16 cell NXjwWYFKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mnq3TY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4yOTF4MzFOwG0> MnHOV2FPT0WU
MOLT-4 cell NX[5PId1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml:4TY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOE41OTJ2IN88US=> MkexV2FPT0WU
MPP-89 cell M33xSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnLYTY5pcWKrdHnvckBw\iCqdX3hckBOWFBvOEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI2QTJ{IN88US=> NH;i[GJUSU6JRWK=
MRK-nu-1 cell M3y2R2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFj6R|JKdmirYnn0bY9vKG:oIHj1cYFvKE2USz3ueU0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53N{W3NkDPxE1? NHPiVJVUSU6JRWK=
MSTO-211H cell NFrFWWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3vHe2lvcGmkaYTpc44hd2ZiaIXtZY4hVVOWTz2yNVFJKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwOE[5JO69VQ>? NWjjU5lKW0GQR1XS
MV-4-11 cell NGjoRpBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHzPO2RKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF|OUG1JO69VQ>? NYiwWXp5W0GQR1XS
NALM-6 cell NYHYZYhKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYjSUVd2UW6qaXLpeIlwdiCxZjDoeY1idiCQQVzNMVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjV4MUC5JO69VQ>? MmfDV2FPT0WU
NB1 cell M2LVcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2P6S2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz64OFM3QSEQvF2= NHXRToZUSU6JRWK=
NB10 cell Ml7zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXH0UXp1UW6qaXLpeIlwdiCxZjDoeY1idiCQQkGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yOzlzNTFOwG0> NVXqN4x{W0GQR1XS
NB12 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVX3UpBsUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVYvPTZ3NjFOwG0> NWXUPZR6W0GQR1XS
NB13 cell NYHVN2h1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{fpW2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuN|EzPzhizszN M3frOnNCVkeHUh?=
NB17 cell MoPQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYnJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkW4NFUyKM7:TR?= NGC5VXpUSU6JRWK=
NB6 cell M4[5WWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIDW[otKdmirYnn0bY9vKG:oIHj1cYFvKE6ENjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVkyOTRizszN NIPnVJdUSU6JRWK=
NCCIT cell NYnlTW5pT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEPyZlRKdmirYnn0bY9vKG:oIHj1cYFvKE6FQ1nUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFEvQDR3MzFOwG0> NH3wcJZUSU6JRWK=
NCI-H1155 cell NYjYO2VTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVW4[YM{UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFEyPTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zND6zOFA5KM7:TR?= MkXOV2FPT0WU
NCI-H1304 cell MkSxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWTJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO M2DhPHNCVkeHUh?=
NCI-H1355 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU\2[ZZCUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{PTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Lkm0NVEh|ryP M1H1b3NCVkeHUh?=
NCI-H1395 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHO5ZZBKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVM6PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3PVUh|ryP NEDIOHpUSU6JRWK=
NCI-H1417 cell M2LxXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIHGflhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVQyPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNke1NlIh|ryP M{K5[3NCVkeHUh?=
NCI-H1436 cell NGSzbI9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkXxTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG0N|Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njh2MUCxJO69VQ>? MV7TRW5ITVJ?
NTERA-S-cl-D1 cell NWK2SlNmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4GxNGlvcGmkaYTpc44hd2ZiaIXtZY4hVlSHUlGtV{1kdC2GMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlg6OzVizszN NYjwdWF1W0GQR1XS
JiyoyeP-2003 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEjrRZFKdmirYnn0bY9vKG:oIHj1cYFvKEqreX;5[XAuOjByMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO2MlYzQDRizszN NWDBRpVoW0GQR1XS

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
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  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID