GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmDBTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG1PFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC56NEe3JO69VQ>? MV7TRW5ITVJ?
NCI-H1694 NVH5O2pZT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGr1SVFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY6PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lki3OFkh|ryP NGH2bpVUSU6JRWK=
NCI-H1963 MnnJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWjJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUm2N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOjd6M{mg{txO NUnjd2IzW0GQR1XS
NCI-H2081 M{W0UGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYPwRYtLUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIxQDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|ND62NFQ1KM7:TR?= NGGw[ZRUSU6JRWK=
NCI-H209 NEjRXJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV;Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvPjJ5MjFOwG0> NHn5e5pUSU6JRWK=
NCI-H2107 M4G4SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3vEe2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVA4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwNkW2NUDPxE1? MWfTRW5ITVJ?
NCI-H2126 MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPTB2Mk[g{txO NHPKU3BUSU6JRWK=
NCI-H2171 M1TVcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1TrW2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVcyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC57NUmzO{DPxE1? MWHTRW5ITVJ?
NCI-H2227 MmXJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1jYR2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNlI4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py56OE[xOkDPxE1? NFf6TFlUSU6JRWK=
NCI-H524 MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkG3TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh5NkOg{txO MlLZV2FPT0WU
NCI-H526 NXvkXnBST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7CUXNKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUSzNUDPxE1? MlHvV2FPT0WU
NCI-H720 NFP6UIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYfJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KN{KwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk41PTF4MTFOwG0> NVrxVGFtW0GQR1XS
NMC-G1 MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXXpXpppUW6qaXLpeIlwdiCxZjDoeY1idiCQTVOtS|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS5yNUe4JO69VQ>? MYTTRW5ITVJ?
NOS-1 cell NGLPc4pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUnJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT64NlI6PCEQvF2= NFTxd45USU6JRWK=
OCI-AML2 cell Mni5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFTabnJKdmirYnn0bY9vKG:oIHj1cYFvKE:FST3BUWwzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTBwOUS5OkDPxE1? MnfkV2FPT0WU
OCUB-M cell M16zdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIjBbodKdmirYnn0bY9vKG:oIHj1cYFvKE:FVVKtUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjJyMTFOwG0> M4OwNHNCVkeHUh?=
ONS-76 cell MoHiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJG9PWy15NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlkyQTFizszN M{\pTnNCVkeHUh?=
OS-RC-2 cell M1rlemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmDMTY5pcWKrdHnvckBw\iCqdX3hckBQWy2UQz2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvOTl3IN88US=> MnfyV2FPT0WU
OVCAR-4 cell M{HCNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXLJcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlcyQDB6IN88US=> MoXpV2FPT0WU
P30-OHK cell Mni0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmXtTY5pcWKrdHnvckBw\iCqdX3hckBROzBvT1jLJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43Ojh5NzFOwG0> NHPlOnRUSU6JRWK=
P30-OHK cell NHvHd5VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXLVbYR3UW6qaXLpeIlwdiCxZjDoeY1idiCSRj2zPFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjB2OUW0JO69VQ>? NIeyVmhUSU6JRWK=
PSN1 cell NXm3NWo5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4j3e2lvcGmkaYTpc44hd2ZiaIXtZY4hWFOQMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNlIyOjZizszN MmizV2FPT0WU
QIMR-WIL cell Ml3PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH;1WHVKdmirYnn0bY9vKG:oIHj1cYFvKFGLTWKtW2lNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC52OUCwOEDPxE1? M3SwcXNCVkeHUh?=
RCC10RGB cell MkfES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH[3XXNKdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOUCzOkDPxE1? MUTTRW5ITVJ?
RKO cell NX3XTlltT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV;RTW9VUW6qaXLpeIlwdiCxZjDoeY1idiCUS1:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE42PjZ{IN88US=> MnLuV2FPT0WU
RL95-2 cell M4PZfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnzhTY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE43PyEQvF2= NXK2ZY1UW0GQR1XS
RPMI-6666 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2fpR2lvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? M3i4eXNCVkeHUh?=
RPMI-8402 cell NYezclhET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3m5NmlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST24OFAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC53OEW2JO69VQ>? MkG1V2FPT0WU
RXF393 cell NHj0T45Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGrJTY1KdmirYnn0bY9vKG:oIHj1cYFvKFK[RkO5N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzl|IN88US=> MoHCV2FPT0WU
Ramos-2G6-4C10 cell M2LReWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mm\2TY5pcWKrdHnvckBw\iCqdX3hckBT[W2xcz2yS|YuPENzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuN|U4KM7:TR?= MnzMV2FPT0WU
SCLC-21H cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml6zTY5pcWKrdHnvckBw\iCqdX3hckBUS0yFLUKxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjFzNEmg{txO MmHyV2FPT0WU
SF126 cell MlTTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{f5SmlvcGmkaYTpc44hd2ZiaIXtZY4hW0ZzMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU45OzJzzszN MWrTRW5ITVJ?
SF268 cell MnTGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnL3TY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uNlMyQDNizszN M2L3V3NCVkeHUh?=
SF539 cell M{TIOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3fsO2lvcGmkaYTpc44hd2ZiaIXtZY4hW0Z3M{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI5PjZzIN88US=> M{HzXHNCVkeHUh?=
SH-4 cell MmXYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2T0VGlvcGmkaYTpc44hd2ZiaIXtZY4hW0hvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuO|U2ODhizszN Mlq5V2FPT0WU
SIG-M5 cell NFroSZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnzHTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU44OjV7IN88US=> M{foW3NCVkeHUh?=
SJSA-1 cell NFzHPGVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFQ2OjZizszN MYHTRW5ITVJ?
SK-LMS-1 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4PTUGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi53OU[1JO69VQ>? MmDsV2FPT0WU
SK-MM-2 cell M4jkcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3nwemlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTV2tNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjN2MEWg{txO NHjGXI9USU6JRWK=
SK-N-DZ cell NUP6NWJtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoK0TY5pcWKrdHnvckBw\iCqdX3hckBUUy2QLVTaJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU41QDNzNDFOwG0> M2rYeXNCVkeHUh?=
SK-NEP-1 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXnJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPTR3NjFOwG0> MWPTRW5ITVJ?
SK-PN-DW cell Mm\jS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1n3UGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPC57N{O2JO69VQ>? M{n4d3NCVkeHUh?=
SNB75 cell M4\G[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVfJcohq[mm2aX;uJI9nKGi3bXHuJHNPSjd3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6wO|c{PyEQvF2= Mlj3V2FPT0WU
SR cell NFvOfIRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEPlVpJKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFAyOzdizszN M2DmN3NCVkeHUh?=
SU-DHL-1 cell Mly2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXTxUJNTUW6qaXLpeIlwdiCxZjDoeY1idiCVVT3ETGwuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{LkezN|Yh|ryP M4XJdXNCVkeHUh?=
SW684 cell MlH0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkL1TY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= M1TT[XNCVkeHUh?=
SW872 cell NV\zcWIxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4L3NmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg5PjV4IN88US=> MkXiV2FPT0WU
SW962 cell MlO3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnjSplKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPzV{MTFOwG0> Mn\oV2FPT0WU
697 cell MoDvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NID0ZolKdmirYnn0bY9vKG:oIHj1cYFvKDZ7NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlk6OSEQvF2= M{P1OXNCVkeHUh?=
8-MG-BA cell M2fPW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVTJcohq[mm2aX;uJI9nKGi3bXHuJFguVUdvQlGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4xPzl|IN88US=> M1nxe3NCVkeHUh?=
A101D cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Moj2TY5pcWKrdHnvckBw\iCqdX3hckBCOTBzRDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFcxOzRizszN Mk\1V2FPT0WU
ACN cell Mn\KS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MULJcohq[mm2aX;uJI9nKGi3bXHuJGFEViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJzLkSzPFch|ryP MmS4V2FPT0WU
AM-38 cell Mkj2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3fCNWlvcGmkaYTpc44hd2ZiaIXtZY4hSU1vM{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI3OzJ5IN88US=> NX7VW5JFW0GQR1XS
ATN-1 cell M3\pU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYK1fYRRUW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd3NUWg{txO NGDxPGZUSU6JRWK=
BB30-HNC cell MoXmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnTUI5KdmirYnn0bY9vKG:oIHj1cYFvKEKEM{CtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwMkWzNkDPxE1? NVnSOlNLW0GQR1XS
BB49-HNC cell MofZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4TTbmlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ2OT3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjByN{i5JO69VQ>? M3PkV3NCVkeHUh?=
human BC-1 cell NVfYbXhKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{X4b2lvcGmkaYTpc44hd2ZiaIXtZY4hSkNvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPVcyODdizszN MUnTRW5ITVJ?
BE-13 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlfWTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= MmHDV2FPT0WU
BL-70 cell M3\ubmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVfJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTdyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFcxOyEQvF2= NF3zWWJUSU6JRWK=
BV-173 cell M{XYVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MonwTY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xPE45QDV7IN88US=> NVnhTY9wW0GQR1XS
Becker cell MlPiS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWXJcohq[mm2aX;uJI9nKGi3bXHuJGJm[2uncjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlk2PDVizszN MXLTRW5ITVJ?
CAL-148 cell NF7mUVJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2fOWmlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO NIXWeoxUSU6JRWK=
TE-10 cell NYO3ZWZvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFKwfppKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDR{MzFOwG0> MVLTRW5ITVJ?
TE-12 cell NW\WTIFnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mm\LTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN M{PJZXNCVkeHUh?=
TE-8 cell M3jYc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT62NFg6KM7:TR?= NXjP[nB3W0GQR1XS
TE-9 cell Mne4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVvvb4VmUW6qaXLpeIlwdiCxZjDoeY1idiCWRT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPjN6MTFOwG0> MmXpV2FPT0WU
TGW cell MkTkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVn6OnViUW6qaXLpeIlwdiCxZjDoeY1idiCWR2egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4{PTd5IN88US=> M{PmVHNCVkeHUh?=
UACC-257 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkjhTY5pcWKrdHnvckBw\iCqdX3hckBWSUOFLUK1O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPzB4MkWg{txO M4K1b3NCVkeHUh?=
WSU-NHL cell MnPjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVO2cnJmUW6qaXLpeIlwdiCxZjDoeY1idiCZU2WtUmhNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjdwMUmwO{DPxE1? M4n5S3NCVkeHUh?=
no-10 cell MmTWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3v6S2lvcGmkaYTpc44hd2ZiaIXtZY4hdm9vMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY3QDR4IN88US=> M4X4e3NCVkeHUh?=
no-11 cell MknQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUnJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuNFI3OyEQvF2= MYrTRW5ITVJ?
CAS-1 cell M1jMV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUPINXhXUW6qaXLpeIlwdiCxZjDoeY1idiCFQWOtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDR5IN88US=> NY\pelhnW0GQR1XS
CCRF-CEM cell NXXrNXRIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWjFPFE{UW6qaXLpeIlwdiCxZjDoeY1idiCFQ2LGMWNGVSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwNkWzPVIh|ryP NGPLbG9USU6JRWK=
CMK cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWTGPXFQUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAyOzJ|IN88US=> NEOyb4ZUSU6JRWK=
COLO-829 cell NGjLeoFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWXJVoI2UW6qaXLpeIlwdiCxZjDoeY1idiCFT1zPMVgzQSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwMkSyNlYh|ryP NFf4SGJUSU6JRWK=
COR-L279 cell M{W1[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4DYXGlvcGmkaYTpc44hd2ZiaIXtZY4hS0:ULVyyO|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjB5M{ig{txO M2n2RXNCVkeHUh?=
CP66-MEL cell NXTQR5JlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3zlb2lvcGmkaYTpc44hd2ZiaIXtZY4hS1B4Nj3NSWwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Pi53NEm3JO69VQ>? MkWzV2FPT0WU
CRO-AP2 cell MnfNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXfJcohq[mm2aX;uJI9nKGi3bXHuJGNTVy2DUEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlM3ODh6IN88US=> MnTWV2FPT0WU
CTV-1 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVLJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= MoDpV2FPT0WU
Calu-6 cell NYizfXJIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYPJcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlU5PiEQvF2= M{eyZ3NCVkeHUh?=
D-247MG cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkPMTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ2N13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43OjhzNDFOwG0> NYjX[YR{W0GQR1XS
D-263MG cell NVvKWpM6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlzuTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ4M13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDVyOTFOwG0> MkjWV2FPT0WU
D-336MG cell NWi2bpR7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXW4NXUyUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54Mki1OEDPxE1? M13ZSnNCVkeHUh?=
D-392MG cell MnLaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYnJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzl{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlQ{ODN7IN88US=> MXHTRW5ITVJ?
D-502MG cell NUmxUlVnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVHJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTB{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlU{PDl{IN88US=> NVnDS2hUW0GQR1XS
D-542MG cell NHXFb4dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1TSXGlvcGmkaYTpc44hd2ZiaIXtZY4hTC13NELNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjNzNUKg{txO MljTV2FPT0WU
DB cell M1PUZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{XYUGlvcGmkaYTpc44hd2ZiaIXtZY4hTEJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Nz6xOFE4KM7:TR?= MV\TRW5ITVJ?
DEL cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYjiNmg3UW6qaXLpeIlwdiCxZjDoeY1idiCGRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlAyQDl6IN88US=> MWfTRW5ITVJ?
DMS-114 cell MmTyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWHhdJR6UW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? MmnnV2FPT0WU
DMS-153 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUHJcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zNUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk46QTJ|IN88US=> NH;l[2FUSU6JRWK=
DOHH-2 cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV\6dmd2UW6qaXLpeIlwdiCxZjDoeY1idiCGT1jIMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjJ{N{[0JO69VQ>? Ml7sV2FPT0WU
DSH1 cell MnW1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmDLTY5pcWKrdHnvckBw\iCqdX3hckBFW0hzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD60N|YzOyEQvF2= Mnr3V2FPT0WU
Daudi cell M1K1R2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlL2TY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN MYjTRW5ITVJ?
EC-GI-10 cell MojtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{P2R2lvcGmkaYTpc44hd2ZiaIXtZY4hTUNvR1mtNVAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01PC5{NUi5JO69VQ>? MnT6V2FPT0WU
ECC4 cell NXW3eHZXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGVESzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mj6xPFk3KM7:TR?= NXLObXJ{W0GQR1XS
EM-2 cell Mlj6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGVONTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkS1OVk1KM7:TR?= NILBWopUSU6JRWK=
ES1 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1rLZWlvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT61OFA5PyEQvF2= MXLTRW5ITVJ?
ES3 cell Mmf0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYrqNWZPUW6qaXLpeIlwdiCxZjDoeY1idiCHU{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk41PzJ7IN88US=> MYnTRW5ITVJ?
ES4 cell M2\U[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjpOmpwUW6qaXLpeIlwdiCxZjDoeY1idiCHU{SgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU4yQTVizszN M3XUO3NCVkeHUh?=
ES6 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{nE[GlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yOFc{OyEQvF2= NXz2bIdsW0GQR1XS
ES7 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVrJcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwMkOxNlQh|ryP Mk\sV2FPT0WU
ES8 cell NWPEdXFmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYfVd|V2UW6qaXLpeIlwdiCxZjDoeY1idiCHU{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlgyQTJ2IN88US=> NXfPbmt7W0GQR1XS
EW-18 cell NUj6N|d3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPPfXhKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPjd3OTFOwG0> Mlr1V2FPT0WU
EW-22 cell NVTYb2VmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Moi1TY5pcWKrdHnvckBw\iCqdX3hckBGXy1{MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3Mlc6PDdizszN NFruNFRUSU6JRWK=
GCIY cell NXfhPGZ5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn3OTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64NFM5QSEQvF2= M2ruOXNCVkeHUh?=
GDM-1 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= MXXTRW5ITVJ?
GI-1 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEjB[G5KdmirYnn0bY9vKG:oIHj1cYFvKEeLLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxPTJ|IN88US=> Ml3iV2FPT0WU
GI-ME-N cell Mn3PS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUTVOI17UW6qaXLpeIlwdiCxZjDoeY1idiCJST3NSU1PKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNEm1NUDPxE1? M3PHcnNCVkeHUh?=
GR-ST cell M{PmXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NED0b2tKdmirYnn0bY9vKG:oIHj1cYFvKEeULWPUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPzlyMjFOwG0> NVfWW|FJW0GQR1XS
GT3TKB cell NFrk[2hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFPoWFFKdmirYnn0bY9vKG:oIHj1cYFvKEeWM2TLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPjB|OEmg{txO MXLTRW5ITVJ?
HAL-01 cell M2G1dGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGhCVC1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uOlk4OTJizszN MXjTRW5ITVJ?
HCC1599 cell NFHIVGxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4XrW2lvcGmkaYTpc44hd2ZiaIXtZY4hUEOFMUW5PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM4NjZyMUGg{txO MnXTV2FPT0WU
HCC2218 cell Mn3IS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoXPTY5pcWKrdHnvckBw\iCqdX3hckBJS0N{MkG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvOzh|NDFOwG0> NXHmRYY3W0GQR1XS
HD-MY-Z cell NEDURVFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYOyN4pZUW6qaXLpeIlwdiCxZjDoeY1idiCKRD3NXU1bKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwMkG0OkDPxE1? M2nnPXNCVkeHUh?=
HL-60 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU\vU2hOUW6qaXLpeIlwdiCxZjDoeY1idiCKTD22NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjJzMUSg{txO MYDTRW5ITVJ?
HOP-62 cell NIDWR|FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF76coNKdmirYnn0bY9vKG:oIHj1cYFvKEiRUD22NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{Njl3Mkeg{txO MVfTRW5ITVJ?
HT cell NWH1NmlQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGDRT|ZKdmirYnn0bY9vKG:oIHj1cYFvKEiWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND60OFMzOSEQvF2= MVfTRW5ITVJ?
HT-144 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmfmTY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlkxPjh4IN88US=> MVLTRW5ITVJ?
HUTU-80 cell Mni4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYHXdYpUUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OEm4OkDPxE1? NXLOcWxTW0GQR1XS
IST-MEL1 cell MlKyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkK2TY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXMNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMzNjlyOE[g{txO MmnRV2FPT0WU
IST-SL1 cell MkD4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mm\hTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4yPzB5OTFOwG0> NHHEN4tUSU6JRWK=
IST-SL2 cell NXzSSVQ4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHrnXlRKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{NjJ4NkC4JO69VQ>? M{DwO3NCVkeHUh?=
K052 cell NETpcFJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFewZ5VKdmirYnn0bY9vKG:oIHj1cYFvKEtyNUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlc2OzBzIN88US=> NYDMcYtjW0GQR1XS
K5 cell MlrGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXvtemdxUW6qaXLpeIlwdiCxZjDoeY1idiCNNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOzMlU6OTVizszN MVHTRW5ITVJ?
KALS-1 cell M4rtfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUTGfFkxUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQS5|OU[5JO69VQ>? MVzTRW5ITVJ?
KARPAS-422 cell NEPUNpNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIfFOWZKdmirYnn0bY9vKG:oIHj1cYFvKEuDUmDBV{01OjJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj65NVQzKM7:TR?= MonJV2FPT0WU
KARPAS-45 cell NYjMUXNlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYTJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTF{NEeg{txO Mo\jV2FPT0WU
KE-37 cell MlfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64N|Uh|ryP M3XicHNCVkeHUh?=
KG-1 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX7RVG1FUW6qaXLpeIlwdiCxZjDoeY1idiCNRz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvQTd3NzFOwG0> NU[zfVdSW0GQR1XS
KGN cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NU[y[pY5UW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PzR{IN88US=> MonhV2FPT0WU
KM12 cell Mkm0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2nsSWlvcGmkaYTpc44hd2ZiaIXtZY4hU01zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOVI6PjRizszN Ml;FV2FPT0WU
KMOE-2 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUTJcohq[mm2aX;uJI9nKGi3bXHuJGtOV0VvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOwMlQ2PDlizszN MUPTRW5ITVJ?
KNS-42 cell M33WXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3PGOmlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUSyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE45OTlzNTFOwG0> MmDqV2FPT0WU
KNS-81-FD cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NULCeZZtUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtPFEuTkRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nz60NlYh|ryP MVHTRW5ITVJ?
KS-1 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJGtUNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwOFYh|ryP NHrWXW5USU6JRWK=
KU812 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2jWSWlvcGmkaYTpc44hd2ZiaIXtZY4hU1V6MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{41QDRizszN M4P1RXNCVkeHUh?=
L-540 cell M1\5O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NInxOWtKdmirYnn0bY9vKG:oIHj1cYFvKExvNUSwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlAvPzR2NTFOwG0> NIHGRY5USU6JRWK=
LAMA-84 cell NF;CcHZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEPUO49KdmirYnn0bY9vKG:oIHj1cYFvKEyDTVGtPFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy54N{SyJO69VQ>? MWLTRW5ITVJ?
LB1047-RCC cell MoPZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M37PeWlvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ6LkO4PFMh|ryP MVrTRW5ITVJ?
LB2241-RCC cell MkLnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWPqdpB{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkKyOFEuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUCuOVU{PiEQvF2= MVnTRW5ITVJ?
LB2518-MEL cell M3H0OGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{HaXGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwN{G0PVbPxE1? NWW2VGx[W0GQR1XS
LB831-BLC cell NYXoU4FDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mmj3TY5pcWKrdHnvckBw\iCqdX3hckBNSjh|MT3CUGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOS5zN{K2JO69VQ>? NF\rWVBUSU6JRWK=
LB996-RCC cell M2Pzemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVm2Z4NLUW6qaXLpeIlwdiCxZjDoeY1idiCOQkm5Ok1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj63OFMyKM7:TR?= NV\kS3RZW0GQR1XS
LC4-1 cell M3PmcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIfC[3BKdmirYnn0bY9vKG:oIHj1cYFvKEyFND2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvQDN2MTFOwG0> NVThUJFnW0GQR1XS
LOUCY cell NYDHOoFLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4nyOGlvcGmkaYTpc44hd2ZiaIXtZY4hVE:XQ2mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlE2Ojd4IN88US=> M3HyXXNCVkeHUh?=
LOXIMVI cell NXX3[W9KT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYPJcohq[mm2aX;uJI9nKGi3bXHuJGxQYEmPVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE4zOTJ{IN88US=> MYDTRW5ITVJ?
LS-123 cell MnjqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEDRdJlKdmirYnn0bY9vKG:oIHj1cYFvKEyVLUGyN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjJ{NUig{txO MWnTRW5ITVJ?
LU-134-A cell NX\ISFR3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGxWNTF|ND3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4yPDB4ODFOwG0> NEDsZ2lUSU6JRWK=
LU-139 cell NYS4[|IzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4fjVmlvcGmkaYTpc44hd2ZiaIXtZY4hVFVvMUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOjF6IN88US=> MWPTRW5ITVJ?
LXF-289 cell M4Lve2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXnJcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{41OzVzzszN NEPlOZVUSU6JRWK=
MC116 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYDJcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuNFg1OSEQvF2= NYXDUJhvW0GQR1XS
MDA-MB-134-VI cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWLJcohq[mm2aX;uJI9nKGi3bXHuJG1FSS2PQj2xN|QuXkliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|OT6yOFg3KM7:TR?= Mn7zV2FPT0WU
MFH-ino cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFzndYNKdmirYnn0bY9vKG:oIHj1cYFvKE2ISD3pco8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ2M{izJO69VQ>? MkS3V2FPT0WU
MHH-NB-11 cell NEPSR3FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYnJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODZ4OTFOwG0> MWHTRW5ITVJ?
ML-2 cell M1;QdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mo\mTY5pcWKrdHnvckBw\iCqdX3hckBOVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFMxPCEQvF2= Mkj5V2FPT0WU
MOLT-13 cell Mn7hS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnvmTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE41OzZ3MzFOwG0> MmDrV2FPT0WU
MOLT-16 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFPvSnBKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStNVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjFzMU[zJO69VQ>? MlzsV2FPT0WU
MOLT-4 cell M4\tXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVXJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0MlQyOjRizszN MlvTV2FPT0WU
MPP-89 cell M3PpXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkCwTY5pcWKrdHnvckBw\iCqdX3hckBOWFBvOEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI2QTJ{IN88US=> NHqzSGNUSU6JRWK=
MRK-nu-1 cell MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4Dx[2lvcGmkaYTpc44hd2ZiaIXtZY4hVVKNLX71MVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjV5NUeyJO69VQ>? NHPsemVUSU6JRWK=
MSTO-211H cell M2\xXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUHJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> M1\rd3NCVkeHUh?=
MV-4-11 cell Ml3qS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnHmTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yOzlzNTFOwG0> NIDOe2VUSU6JRWK=
NALM-6 cell NF;peVdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFvsZ2RKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPTZzMEmg{txO MXjTRW5ITVJ?
NB1 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPKTY5pcWKrdHnvckBw\iCqdX3hckBPSjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lki0N|Y6KM7:TR?= NW\RbIY4W0GQR1XS
NB10 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIrvXGZKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE{QTF3IN88US=> MoD1V2FPT0WU
NB12 cell MmfCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFv5cVdKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOk42PjV4IN88US=> Mk\XV2FPT0WU
NB13 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJG5DOTNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{LkOxNlc5KM7:TR?= M3TOfXNCVkeHUh?=
NB17 cell NWP3ZmQ1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mmn1TY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= NF;tfZpUSU6JRWK=
NB6 cell M2rh[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHixd2JKdmirYnn0bY9vKG:oIHj1cYFvKE6ENjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVkyOTRizszN MV;TRW5ITVJ?
NCCIT cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXnJcohq[mm2aX;uJI9nKGi3bXHuJG5ES0mWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEGuPFQ2OyEQvF2= MoXsV2FPT0WU
NCI-H1155 cell NU\MS2xpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkDyTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGxOVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC5|NEC4JO69VQ>? NVfGeoI3W0GQR1XS
NCI-H1304 cell NYXxVZM{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NImzUllKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVMxPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFzLki5PFIh|ryP MVjTRW5ITVJ?
NCI-H1355 cell NHXybGNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV7qUYR2UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{PTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Lkm0NVEh|ryP MXnTRW5ITVJ?
NCI-H1395 cell NFi5RXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXjpOFVxUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{QTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mj64O|k2KM7:TR?= M1m1OXNCVkeHUh?=
NCI-H1417 cell Mk[wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MY\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSxO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjd3MkKg{txO M3PLe3NCVkeHUh?=
NCI-H1436 cell M4XLeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH3KcFFKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVQ{PiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwOESxNFEh|ryP Mnn0V2FPT0WU
NTERA-S-cl-D1 cell NYDoSIhsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4XUUmlvcGmkaYTpc44hd2ZiaIXtZY4hVlSHUlGtV{1kdC2GMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlg6OzVizszN NGnh[3NUSU6JRWK=
JiyoyeP-2003 cell M1L2U2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoPhTY5pcWKrdHnvckBw\iCqdX3hckBLcXmxeXXQMVIxODNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nj62Nlg1KM7:TR?= M3TsZnNCVkeHUh?=

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
+ Expand
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID