GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

Size Price Stock Quantity  
USD 97 In stock
USD 397 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYnpSZFbUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE2QDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zOD64OFc4KM7:TR?= NX72VoN{W0GQR1XS
NCI-H1694 NUm2O4l6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIrrTHBKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY6PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lki3OFkh|ryP NWHRfoFwW0GQR1XS
NCI-H1963 MkDMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXfkZ4x[UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE6PjNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkK3PFM6KM7:TR?= NVPuWpIxW0GQR1XS
NCI-H2081 NVzHWWlqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnP5TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC54MES0JO69VQ>? NE\MTplUSU6JRWK=
NCI-H209 MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmXUTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjZ{N{Kg{txO NHm3cnRUSU6JRWK=
NCI-H2107 NFn2c5BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHzMTZBKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlExPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ3Lk[1OlEh|ryP NYXmd5hWW0GQR1XS
NCI-H2126 NVrWT3ZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFnLXY9KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlEzPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTZwNUC0NlYh|ryP NH;nTGpUSU6JRWK=
NCI-H2171 NILyV4VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkWxTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxO|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjl3OUO3JO69VQ>? M{HIbHNCVkeHUh?=
NCI-H2227 M3r6Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHHEe2JKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlIzPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwOEi2NVYh|ryP MkXwV2FPT0WU
NCI-H524 NF7WNGlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmG5TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh5NkOg{txO NGHa[m1USU6JRWK=
NCI-H526 Ml2wS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1;qVmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVi1NlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC53NEOxJO69VQ>? MW\TRW5ITVJ?
NCI-H720 MmK2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmfETY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEeyNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDVzNkGg{txO Mlr2V2FPT0WU
NMC-G1 M{SyXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkXTTY5pcWKrdHnvckBw\iCqdX3hckBPVUNvR{GgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xOU4xPTd6IN88US=> MVXTRW5ITVJ?
NOS-1 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUjzRoJiUW6qaXLpeIlwdiCxZjDoeY1idiCQT2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvQDJ{OUSg{txO NWLISGd2W0GQR1XS
OCI-AML2 cell NYf6V2ZRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH;LVINKdmirYnn0bY9vKG:oIHj1cYFvKE:FST3BUWwzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTBwOUS5OkDPxE1? NGDzN4xUSU6JRWK=
OCUB-M cell NX:2NnIxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVzwXlM6UW6qaXLpeIlwdiCxZjDoeY1idiCRQ2XCMW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy5{MEGg{txO MWjTRW5ITVJ?
ONS-76 cell NH3GO5lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmDBTY5pcWKrdHnvckBw\iCqdX3hckBQVlNvN{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46OTlzIN88US=> MoPsV2FPT0WU
OS-RC-2 cell MmW2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUnRdHlwUW6qaXLpeIlwdiCxZjDoeY1idiCRUz3SR{0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDZwMUm1JO69VQ>? M{faeXNCVkeHUh?=
OVCAR-4 cell NIr0NI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{LGSGlvcGmkaYTpc44hd2ZiaIXtZY4hV1[FQWKtOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPzF6MEig{txO NFK1c4ZUSU6JRWK=
P30-OHK cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFH2dWhKdmirYnn0bY9vKG:oIHj1cYFvKFB|MD3PTGsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjZ{OEe3JO69VQ>? MoG2V2FPT0WU
P30-OHK cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEXZb4xKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvODR7NUSg{txO MWTTRW5ITVJ?
PSN1 cell NHO5cFFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUfWeoU4UW6qaXLpeIlwdiCxZjDoeY1idiCSU16xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok4zOjF{NjFOwG0> MXPTRW5ITVJ?
QIMR-WIL cell NEDmXYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXG2d5l[UW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEmwNFQh|ryP NIH6UVhUSU6JRWK=
RCC10RGB cell M2XZN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYfJcohq[mm2aX;uJI9nKGi3bXHuJHJESzFyUlfCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvQTB|NjFOwG0> NHzj[m9USU6JRWK=
RKO cell NXK5OI41T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmPTTY5pcWKrdHnvckBw\iCqdX3hckBTU09iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OlYzKM7:TR?= MXHTRW5ITVJ?
RL95-2 cell M{TUXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmTlTY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE43PyEQvF2= MknrV2FPT0WU
RPMI-6666 cell NGPyO3hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2rkTmlvcGmkaYTpc44hd2ZiaIXtZY4hWlCPST22OlY3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwNUKzOkDPxE1? NYO0cY86W0GQR1XS
RPMI-8402 cell NWG5cms3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIq3fYRKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? M2TTeXNCVkeHUh?=
RXF393 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXX1c25JUW6qaXLpeIlwdiCxZjDoeY1idiCUWF[zPVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN7MzFOwG0> MkPBV2FPT0WU
Ramos-2G6-4C10 cell NXS2T4xKT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXT1SldSUW6qaXLpeIlwdiCxZjDoeY1idiCUYX3vd{0zTzZvNFOxNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzV5IN88US=> MXfTRW5ITVJ?
SCLC-21H cell M{fyWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHNEVENvMkHIJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{43OTF2OTFOwG0> Ml30V2FPT0WU
SF126 cell NIfkRmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3;NNGlvcGmkaYTpc44hd2ZiaIXtZY4hW0ZzMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU45OzJzzszN NGHlfldUSU6JRWK=
SF268 cell NH74ZolIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHnDZmNKdmirYnn0bY9vKG:oIHj1cYFvKFOIMk[4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok4zOzF6MzFOwG0> MUTTRW5ITVJ?
SF539 cell M3HTW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHnh[G9KdmirYnn0bY9vKG:oIHj1cYFvKFOINUO5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zQDZ4MTFOwG0> M2q3dHNCVkeHUh?=
SH-4 cell NYn6WpFuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFrtSVRKdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlc2PTB6IN88US=> M1TkcXNCVkeHUh?=
SIG-M5 cell MoDhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXPJcohq[mm2aX;uJI9nKGi3bXHuJHNKTy2PNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGxMlczPTlizszN MVLTRW5ITVJ?
SJSA-1 cell M{W2O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWWyNnFiUW6qaXLpeIlwdiCxZjDoeY1idiCVSmPBMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB2NUK2JO69VQ>? NV25fpd7W0GQR1XS
SK-LMS-1 cell NEn4NXBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX7Jcohq[mm2aX;uJI9nKGi3bXHuJHNMNUyPUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvPTl4NTFOwG0> MUHTRW5ITVJ?
SK-MM-2 cell NVLze3diT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXnKVVBkUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NUU0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwM{SwOUDPxE1? MmLmV2FPT0WU
SK-N-DZ cell Ml;MS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1zkSmlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTj3EXkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvPDh|MUSg{txO NFvKb2FUSU6JRWK=
SK-NEP-1 cell MmDNS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI\wd3BKdmirYnn0bY9vKG:oIHj1cYFvKFONLV7FVE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwNUS1OkDPxE1? MkjaV2FPT0WU
SK-PN-DW cell M3L3[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{C5[mlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvUF6tSHch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPC57N{O2JO69VQ>? NEDYTYdUSU6JRWK=
SNB75 cell NVHEepBnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV3Pem1qUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvODd5M{eg{txO Mn20V2FPT0WU
SR cell M1TlfGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1HhZmlvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwNFE{PyEQvF2= NV;1eWVGW0GQR1XS
SU-DHL-1 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3LGRmlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi55M{O2JO69VQ>? M1X1dnNCVkeHUh?=
SW684 cell NVrRS3g3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVvJcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNFEyKM7:TR?= Mmj3V2FPT0WU
SW872 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFn5XFhKdmirYnn0bY9vKG:oIHj1cYFvKFOZOEeyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45QDZ3NjFOwG0> MVfTRW5ITVJ?
SW962 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmftTY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlc2OjFizszN MXTTRW5ITVJ?
697 cell NFTQeldIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mof2TY5pcWKrdHnvckBw\iCqdX3hckA3QTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkK5PVEh|ryP Mne3V2FPT0WU
8-MG-BA cell Ml7rS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH61WXVKdmirYnn0bY9vKG:oIHj1cYFvKDhvTVetRmEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy5yN{mzJO69VQ>? NV3YfHU2W0GQR1XS
A101D cell NXLjPHNPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NITo[WJKdmirYnn0bY9vKG:oIHj1cYFvKEFzMEHEJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45PzB|NDFOwG0> NGfqeZBUSU6JRWK=
ACN cell M4G1bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXHJcohq[mm2aX;uJI9nKGi3bXHuJGFEViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJzLkSzPFch|ryP MoXsV2FPT0WU
AM-38 cell NVjGN5M3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4LFfGlvcGmkaYTpc44hd2ZiaIXtZY4hSU1vM{igZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlI3OzJ5IN88US=> M4H0eHNCVkeHUh?=
ATN-1 cell M1;zb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NW\WO4t1UW6qaXLpeIlwdiCxZjDoeY1idiCDVF6tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njd3NUWg{txO Mn3nV2FPT0WU
BB30-HNC cell NXnmbW9DT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3KzfmlvcGmkaYTpc44hd2ZiaIXtZY4hSkJ|MD3IUmMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{NUOyJO69VQ>? NIXBUpFUSU6JRWK=
BB49-HNC cell NITh[VZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGD0SIZKdmirYnn0bY9vKG:oIHj1cYFvKEKENEmtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMEe4PUDPxE1? MojQV2FPT0WU
human BC-1 cell NVe3NFh7T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmLPTY5pcWKrdHnvckBw\iCqdX3hckBDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65O|ExPyEQvF2= NVL3TZh5W0GQR1XS
BE-13 cell NWf0e2QyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NG\mVJFKdmirYnn0bY9vKG:oIHj1cYFvKEKHLUGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yPDB6Md88US=> M1TR[3NCVkeHUh?=
BL-70 cell MkHzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3rVbWlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvN{CgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlQxPzB|IN88US=> NIOyZo5USU6JRWK=
BV-173 cell NX\je3BLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVrJcohq[mm2aX;uJI9nKGi3bXHuJGJXNTF5MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG4Mlg5PTlizszN M4\WcXNCVkeHUh?=
Becker cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUXJcohq[mm2aX;uJI9nKGi3bXHuJGJm[2uncjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlk2PDVizszN NID5VYhUSU6JRWK=
CAL-148 cell MnzzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWLJcohq[mm2aX;uJI9nKGi3bXHuJGNCVC1zNEigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOU43PTV5IN88US=> MVjTRW5ITVJ?
TE-10 cell M2TyUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHLJXo1KdmirYnn0bY9vKG:oIHj1cYFvKFSHLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvQDR{MzFOwG0> M3zYWnNCVkeHUh?=
TE-12 cell NXjrc|NJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mny5TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN NF71S2JUSU6JRWK=
TE-8 cell NIn1fFhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWLJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT62NFg6KM7:TR?= MmfKV2FPT0WU
TE-9 cell M{n3fGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1O1emlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvOTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO2MlY{QDFizszN NEjIfXhUSU6JRWK=
TGW cell M1T3[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHXidZNKdmirYnn0bY9vKG:oIHj1cYFvKFSJVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlM2PzdizszN NVjhXVJlW0GQR1XS
UACC-257 cell NUHhdFlET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUjJcohq[mm2aX;uJI9nKGi3bXHuJHVCS0NvMkW3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44ODZ{NTFOwG0> M2ricnNCVkeHUh?=
WSU-NHL cell M333TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHy4Z2ZKdmirYnn0bY9vKG:oIHj1cYFvKFeVVT3OTGwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPy5zOUC3JO69VQ>? NGqzXWVUSU6JRWK=
no-10 cell MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NG\lW5JKdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Pjh2NjFOwG0> NXH5Top3W0GQR1XS
no-11 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1e5R2lvcGmkaYTpc44hd2ZiaIXtZY4hdm9vMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{4xOjZ|IN88US=> MWrTRW5ITVJ?
CAS-1 cell NX\5TWdCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH22NI9KdmirYnn0bY9vKG:oIHj1cYFvKEODUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PDdizszN MnPrV2FPT0WU
CCRF-CEM cell NYe5TYJRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2nJeWlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZ3M{myJO69VQ>? MXrTRW5ITVJ?
CMK cell M3LnO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH3VWJFKdmirYnn0bY9vKG:oIHj1cYFvKEOPSzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFE{OjNizszN NVf4TGdNW0GQR1XS
COLO-829 cell M4HCR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXzJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPDJ{NjFOwG0> NW\5PHhNW0GQR1XS
COR-L279 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGXZUIVKdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5yN{O4JO69VQ>? Mm[2V2FPT0WU
CP66-MEL cell MoiwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJGNRPjZvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPTR7NzFOwG0> MkDEV2FPT0WU
CRO-AP2 cell M4Hvb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHHXe4lKdmirYnn0bY9vKG:oIHj1cYFvKEOUTz3BVFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjN4MEi4JO69VQ>? M4nxcHNCVkeHUh?=
CTV-1 cell MnLWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIDUTHpKdmirYnn0bY9vKG:oIHj1cYFvKEOWVj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlMvQTF2NTFOwG0> MVjTRW5ITVJ?
Calu-6 cell MnG3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{f6[2lvcGmkaYTpc44hd2ZiaIXtZY4hS2GudT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPTh4IN88US=> NYOz[lFHW0GQR1XS
D-247MG cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjR5TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlYzQDF2IN88US=> NWjqcFNLW0GQR1XS
D-263MG cell Ml;VS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXLJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA5PTB7IN88US=> MYXTRW5ITVJ?
D-336MG cell NHvibI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFTGSZdKdmirYnn0bY9vKG:oIHj1cYFvKERvM{O2UWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ{OEW0JO69VQ>? MmDXV2FPT0WU
D-392MG cell M3LFVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVjWdZRFUW6qaXLpeIlwdiCxZjDoeY1idiCGLUO5Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52M{CzPUDPxE1? MYXTRW5ITVJ?
D-502MG cell NHTxNYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1;qdmlvcGmkaYTpc44hd2ZiaIXtZY4hTC13MELNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvPTN2OUKg{txO MknPV2FPT0WU
D-542MG cell MkHRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3[5UGlvcGmkaYTpc44hd2ZiaIXtZY4hTC13NELNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjNzNUKg{txO NFT3dnpUSU6JRWK=
DB cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MofNTY5pcWKrdHnvckBw\iCqdX3hckBFSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR5LkG0NVch|ryP M1\zRXNCVkeHUh?=
DEL cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHr2SVhKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNFE5QThizszN Mn;lV2FPT0WU
DMS-114 cell MoXaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXT3[ZFWUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? M{iwdXNCVkeHUh?=
DMS-153 cell NWfvUodnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2L6N2lvcGmkaYTpc44hd2ZiaIXtZY4hTE2VLUG1N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQzNjl7MkOg{txO NFzETXJUSU6JRWK=
DOHH-2 cell NYTqeIl{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGDvcGtKdmirYnn0bY9vKG:oIHj1cYFvKESRSFitNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOjJ5NkSg{txO NUnGVHZ3W0GQR1XS
DSH1 cell MmjaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnTUTY5pcWKrdHnvckBw\iCqdX3hckBFW0hzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD60N|YzOyEQvF2= MnnpV2FPT0WU
Daudi cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTBXJBWUW6qaXLpeIlwdiCxZjDoeY1idiCGYYXkbUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvODl6MEKg{txO NHPQdlJUSU6JRWK=
EC-GI-10 cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXnJcohq[mm2aX;uJI9nKGi3bXHuJGVENUeLLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFQvOjV6OTFOwG0> NHTZTYxUSU6JRWK=
ECC4 cell NIjTTYtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3r0UmlvcGmkaYTpc44hd2ZiaIXtZY4hTUOFNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlE5QTZizszN M1jKSXNCVkeHUh?=
EM-2 cell M{PLWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXGzNIVkUW6qaXLpeIlwdiCxZjDoeY1idiCHTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk41PTV7NDFOwG0> MnH4V2FPT0WU
ES1 cell Mnz6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MonUTY5pcWKrdHnvckBw\iCqdX3hckBGWzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkW0NFg4KM7:TR?= NIXMbGJUSU6JRWK=
ES3 cell MkTMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mlf0TY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj60O|I6KM7:TR?= NVX0ZXpIW0GQR1XS
ES4 cell MnrvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVjJcohq[mm2aX;uJI9nKGi3bXHuJGVUPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN3LkG5OUDPxE1? NYTWR|lsW0GQR1XS
ES6 cell NV\hSW1WT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYDWVFFpUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1PzN|IN88US=> NH6zSYtUSU6JRWK=
ES7 cell NIXEV3ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mnr3TY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkKzNVI1KM7:TR?= NXv5SW9zW0GQR1XS
ES8 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkC2TY5pcWKrdHnvckBw\iCqdX3hckBGWzhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkixPVI1KM7:TR?= MYTTRW5ITVJ?
EW-18 cell NXPnUJRDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWnJcohq[mm2aX;uJI9nKGi3bXHuJGVYNTF6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuOlc2QSEQvF2= NWG5fXRkW0GQR1XS
EW-22 cell NGDRdHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYrJcohq[mm2aX;uJI9nKGi3bXHuJGVYNTJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuO|k1PyEQvF2= NH7sWHFUSU6JRWK=
GCIY cell M4jJN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkfYTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64NFM5QSEQvF2= M1;Lc3NCVkeHUh?=
GDM-1 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2D4NWlvcGmkaYTpc44hd2ZiaIXtZY4hT0SPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlM6OTl4IN88US=> NHTzd5RUSU6JRWK=
GI-1 cell NFfJd5dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NX;hPFdHUW6qaXLpeIlwdiCxZjDoeY1idiCJST2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODV{MzFOwG0> MlLRV2FPT0WU
GI-ME-N cell NXG5eYFiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmrYTY5pcWKrdHnvckBw\iCqdX3hckBIUS2PRT3OJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPDl3MTFOwG0> M2rhW3NCVkeHUh?=
GR-ST cell NVnyUlZ2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXvISpQ2UW6qaXLpeIlwdiCxZjDoeY1idiCJUj3TWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njd7MEKg{txO MoO5V2FPT0WU
GT3TKB cell NHHZ[o1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoC0TY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlYxOzh7IN88US=> M{T2R3NCVkeHUh?=
HAL-01 cell NE\0S3dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUjGfVdOUW6qaXLpeIlwdiCxZjDoeY1idiCKQVytNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF03NjZ7N{GyJO69VQ>? NHPnbHdUSU6JRWK=
HCC1599 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUDJcohq[mm2aX;uJI9nKGi3bXHuJGhESzF3OUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zO{43ODFzIN88US=> MnLtV2FPT0WU
HCC2218 cell MojxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWjJcohq[mm2aX;uJI9nKGi3bXHuJGhESzJ{MUigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{4{QDN2IN88US=> NX7WfFBkW0GQR1XS
HD-MY-Z cell NHfneHFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoXBTY5pcWKrdHnvckBw\iCqdX3hckBJTC2PWT3aJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlUvOjF2NjFOwG0> NGXV[oNUSU6JRWK=
HL-60 cell M2PVOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYrZV3pCUW6qaXLpeIlwdiCxZjDoeY1idiCKTD22NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjJzMUSg{txO NEHoPG9USU6JRWK=
HOP-62 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnvMTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PTJ5IN88US=> NILCcodUSU6JRWK=
HT cell M16zcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlrkTY5pcWKrdHnvckBw\iCqdX3hckBJXCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNESzNlEh|ryP MVTTRW5ITVJ?
HT-144 cell MlKzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{LyeWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE46ODZ6NjFOwG0> MmXTV2FPT0WU
HUTU-80 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoHOTY5pcWKrdHnvckBw\iCqdX3hckBJXVSXLUiwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{44QDl6NjFOwG0> M4qzT3NCVkeHUh?=
IST-MEL1 cell NEfmV|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NI\EWHVKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3NSWwyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzJwOUC4OkDPxE1? NH7LbWZUSU6JRWK=
IST-SL1 cell Mm\3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M13BTWlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLWPMNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvOTdyN{mg{txO NXPNcFVxW0GQR1XS
IST-SL2 cell M2G3bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlfDTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvU1yyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPjZyODFOwG0> MWDTRW5ITVJ?
K052 cell M1\HU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mkf5TY5pcWKrdHnvckBw\iCqdX3hckBMODV{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD63OVMxOSEQvF2= Mn30V2FPT0WU
K5 cell NGq5bZNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmX1TY5pcWKrdHnvckBw\iCqdX3hckBMPSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN|LkW5NVUh|ryP NHTle2tUSU6JRWK=
KALS-1 cell M37HdWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MknMTY5pcWKrdHnvckBw\iCqdX3hckBMSUyVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yPU4{QTZ7IN88US=> NFLXPGJUSU6JRWK=
KARPAS-422 cell M2rLV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX3Jcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20NlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Oi57MUSyJO69VQ>? NXnMW29VW0GQR1XS
KARPAS-45 cell M2j2O2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{PObmlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQ2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5zMUK0O{DPxE1? MmTqV2FPT0WU
KE-37 cell NH7E[5BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXjwNWR3UW6qaXLpeIlwdiCxZjDoeY1idiCNRT2zO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVkvQDN3IN88US=> MmfxV2FPT0WU
KG-1 cell NH6xPGlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2DsbGlvcGmkaYTpc44hd2ZiaIXtZY4hU0dvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlk4PTdizszN M2ryRnNCVkeHUh?=
KGN cell MoO1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEi1VWJKdmirYnn0bY9vKG:oIHj1cYFvKEuJTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVY4PDJizszN Mo\sV2FPT0WU
KM12 cell NITYcnNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUfJcohq[mm2aX;uJI9nKGi3bXHuJGtOOTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkWyPVY1KM7:TR?= M4fXPXNCVkeHUh?=
KMOE-2 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVrJcohq[mm2aX;uJI9nKGi3bXHuJGtOV0VvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOwMlQ2PDlizszN MWXTRW5ITVJ?
KNS-42 cell NXzoO2txT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVX6TnJPUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjhzOUG1JO69VQ>? NHzRfW5USU6JRWK=
KNS-81-FD cell M4qweGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MknyTY5pcWKrdHnvckBw\iCqdX3hckBMVlNvOEGtSmQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py52Mk[g{txO NUH4VoFPW0GQR1XS
KS-1 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LuXGlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFA1PiEQvF2= MU\TRW5ITVJ?
KU812 cell M3T1XWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlzHTY5pcWKrdHnvckBw\iCqdX3hckBMXThzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlQ5PCEQvF2= MYPTRW5ITVJ?
L-540 cell MlfPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV\RfI84UW6qaXLpeIlwdiCxZjDoeY1idiCOLUW0NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjd2NEWg{txO MYTTRW5ITVJ?
LAMA-84 cell MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFLTV3JKdmirYnn0bY9vKG:oIHj1cYFvKEyDTVGtPFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy54N{SyJO69VQ>? NFPaZ5JUSU6JRWK=
LB1047-RCC cell Mk\nS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2HxWmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJzMES3MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ6LkO4PFMh|ryP MUTTRW5ITVJ?
LB2241-RCC cell NInoZ4ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXPJcohq[mm2aX;uJI9nKGi3bXHuJGxDOjJ2MT3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC53NUO2JO69VQ>? NUDwOox6W0GQR1XS
LB2518-MEL cell NICxWmtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYjiOmdoUW6qaXLpeIlwdiCxZjDoeY1idiCOQkK1NVguVUWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63NVQ6Ps7:TR?= MYHTRW5ITVJ?
LB831-BLC cell M1;OR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFy0c3JKdmirYnn0bY9vKG:oIHj1cYFvKEyEOEOxMWJNSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFzLkG3NlYh|ryP MlnNV2FPT0WU
LB996-RCC cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml6yTY5pcWKrdHnvckBw\iCqdX3hckBNSjl7Nj3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi55NEOxJO69VQ>? NEPrO21USU6JRWK=
LC4-1 cell NFLyTHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETuXnJKdmirYnn0bY9vKG:oIHj1cYFvKEyFND2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|IvQDN2MTFOwG0> MnzxV2FPT0WU
LOUCY cell M1ThNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmXJTY5pcWKrdHnvckBw\iCqdX3hckBNV1WFWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVUzPzZizszN NF\zcVBUSU6JRWK=
LOXIMVI cell MnG0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWn5eGZiUW6qaXLpeIlwdiCxZjDoeY1idiCOT2jJUXZKKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzBwMkGyNkDPxE1? MUjTRW5ITVJ?
LS-123 cell NF70e4ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXzJcohq[mm2aX;uJI9nKGi3bXHuJGxUNTF{MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlIzPThizszN Ml\TV2FPT0WU
LU-134-A cell NHLET5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoqyTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{StRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOTRyNkig{txO Ml;VV2FPT0WU
LU-139 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXrFOolpUW6qaXLpeIlwdiCxZjDoeY1idiCOVT2xN|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{MUig{txO NWDMfY9pW0GQR1XS
LXF-289 cell NIrCUFBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEm4OXJKdmirYnn0bY9vKG:oIHj1cYFvKEy[Rj2yPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPy52M{Wx{txO MWTTRW5ITVJ?
MC116 cell NHHsUJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHe4cnZKdmirYnn0bY9vKG:oIHj1cYFvKE2FMUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFUvODh2MTFOwG0> NFW3NWhUSU6JRWK=
MDA-MB-134-VI cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3fWWGlvcGmkaYTpc44hd2ZiaIXtZY4hVUSDLV3CMVE{PC2YSTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlI1QDZizszN NVz0SGdFW0GQR1XS
MFH-ino cell MnHUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MULJcohq[mm2aX;uJI9nKGi3bXHuJG1HUC2rbn:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY1Ozh|IN88US=> M1Hy[3NCVkeHUh?=
MHH-NB-11 cell M3f4WGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKGi3bXHuJG1JUC2QQj2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODZ4OTFOwG0> MmC4V2FPT0WU
ML-2 cell M3LCbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NY[1UlZ1UW6qaXLpeIlwdiCxZjDoeY1idiCPTD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODNyNDFOwG0> M4nRSnNCVkeHUh?=
MOLT-13 cell MYXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3\CSmlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvPDN4NUOg{txO Ml3hV2FPT0WU
MOLT-16 cell NVL5ZVZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;FfGlvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTFzNkOg{txO MmW1V2FPT0WU
MOLT-4 cell NXHyT45rT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXvoT5JWUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC52MUK0JO69VQ>? MofjV2FPT0WU
MPP-89 cell M332XWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYnT[ndtUW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ3OUKyJO69VQ>? MV\TRW5ITVJ?
MRK-nu-1 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlzrTY5pcWKrdHnvckBw\iCqdX3hckBOWktvboWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPTd3N{Kg{txO NXjzVZZUW0GQR1XS
MSTO-211H cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXLJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> MVPTRW5ITVJ?
MV-4-11 cell NGS2SpZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF\vWoRKdmirYnn0bY9vKG:oIHj1cYFvKE2YLUStNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF|OUG1JO69VQ>? NEDzZYdUSU6JRWK=
NALM-6 cell NUez[VlGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWjJcohq[mm2aX;uJI9nKGi3bXHuJG5CVE1vNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOVYyODlizszN MnqxV2FPT0WU
NB1 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYfJcohq[mm2aX;uJI9nKGi3bXHuJG5DOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTNwOESzOlkh|ryP NUXEXGN{W0GQR1XS
NB10 cell MmrFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH3Tb5pKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE{QTF3IN88US=> M4[3U3NCVkeHUh?=
NB12 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2LO[GlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG2MlU3PTZizszN NF25fXhUSU6JRWK=
NB13 cell NFrLfHVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHPjV|VKdmirYnn0bY9vKG:oIHj1cYFvKE6EMUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlMyOjd6IN88US=> NXfIPYJCW0GQR1XS
NB17 cell NYqwXJZyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4TVc2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOVgxPTFizszN MkjlV2FPT0WU
NB6 cell MnPCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoT3TY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkW5NVE1KM7:TR?= NFzSenNUSU6JRWK=
NCCIT cell NYftRohTT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUnJcohq[mm2aX;uJI9nKGi3bXHuJG5ES0mWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEGuPFQ2OyEQvF2= Mo\1V2FPT0WU
NCI-H1155 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M13wfGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixNVU2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTRwM{SwPEDPxE1? MlG2V2FPT0WU
NCI-H1304 cell MWHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV[wWotJUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{ODRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT64PVgzKM7:TR?= M4jrNHNCVkeHUh?=
NCI-H1355 cell M3nIVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mnv3TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzOVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Njl2MUGg{txO MWjTRW5ITVJ?
NCI-H1395 cell NEPMXmdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2Xx[2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|k2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwOEe5OUDPxE1? NXizUmxOW0GQR1XS
NCI-H1417 cell M2HwUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSxO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjd3MkKg{txO NHTBTYRUSU6JRWK=
NCI-H1436 cell M1nvd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M36xNmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFM3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy56NEGwNUDPxE1? MoeyV2FPT0WU
NTERA-S-cl-D1 cell Mm\mS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEjER2FKdmirYnn0bY9vKG:oIHj1cYFvKE6WRWLBMXMu[2xvREGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk45QTN3IN88US=> NGnVW2tUSU6JRWK=
JiyoyeP-2003 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGpqgW:7ZWCtNlAxOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN4Lk[yPFQh|ryP NXy2c3RPW0GQR1XS

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
+ Expand
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

ROCK Signaling Pathway Map

Related ROCK Products0

Tags: buy GSK269962A HCl | GSK269962A HCl supplier | purchase GSK269962A HCl | GSK269962A HCl cost | GSK269962A HCl manufacturer | order GSK269962A HCl | GSK269962A HCl distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID