Catalog No.S2433 Synonyms: BSO, DL-Buthionine-(S,R)-sulfoximine

For research use only.

DL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine) is an inhibitor of glutathione (GSH) synthesis.

DL-Buthionine-Sulfoximine Chemical Structure

CAS No. 5072-26-4

Selleck's DL-Buthionine-Sulfoximine has been cited by 1 Publication

Purity & Quality Control

Choose Selective Glutathione Inhibitors

Biological Activity

Description DL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine) is an inhibitor of glutathione (GSH) synthesis.
GSH [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 222.31


CAS No. 5072-26-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCCCS(=N)(=O)CCC(C(=O)O)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01890551 Completed Other: Dynamic kine-mri Affected and Unaffected Knee in Adoloescent Kuopio University Hospital January 1998 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy DL-Buthionine-Sulfoximine | DL-Buthionine-Sulfoximine supplier | purchase DL-Buthionine-Sulfoximine | DL-Buthionine-Sulfoximine cost | DL-Buthionine-Sulfoximine manufacturer | order DL-Buthionine-Sulfoximine | DL-Buthionine-Sulfoximine distributor