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Dimethyl pimelimidate dihydrochloride

Name: Dimethyl pimelimidate dihydrochloride
Brand: Selleck Chemicals
SKU: E2999
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E2999

Dimethyl pimelimidate dihydrochloride (DMP) is a homobifunctional amine-reactive crosslinker which is readily hydrolyzed at neutral pH.

Chemical Structure

Molecular Weight: 259.17

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Quality Control

Batch: E299901 DMSO]45 mg/mL]false]Water]45 mg/mL]false]Ethanol]45 mg/mL]false Purity: 99.00%

Cited in Nature Medicine for its top-tier quality
COA
SDS
Datasheet

99.00

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Solubility

In vitro
Batch:

DMSO : 45 mg/mL (173.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 45 mg/mL

Ethanol : 45 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	259.17	Formula	C₉H₁₈N₂O₂.2ClH	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	58537-94-3	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/11326019/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05622643	Recruiting	Multiple Sclerosis	EDMUS Foundation	January 19 2023	--
NCT04600726	Unknown status	Older Adults With Mild Neurocognitive Disorders\|Older Adults With Non-communicable Diseases\|Healthy Age-matched Older Adults	The Hong Kong Polytechnic University\|Department of Neuroscience Psychology and Behavior. The University of Leicester\|School of Psychology The University of Nottingham\|The Alice Ho Miu Ning Nethersole Hospital	February 1 2021	--
NCT04098575	Completed	Diabetes Mellitus Type 2	Boehringer Ingelheim	September 16 2019	--
NCT02809417	Completed	Polypathology	Centre Hospitalier Universitaire de Nice	January 28 2016	--

Tech Support

Handling Instructions

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