Desogestrel

Catalog No.S4638 Synonyms: Cerazette, Desogen, Desogestrelum, Org-2969

Desogestrel Chemical Structure

Molecular Weight(MW): 310.47

Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.

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Biological Activity

Description Desogestrel is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
In vivo Desogestrel is extensively metabolized after oral administration to rats and dogs; In rats, desogestrel is metabolized mainly at the C3, C5, C11, and C15 positions. An hydroxy group is introduced at the 15α-position of desogestrel, followed by conjugation with glucuronic acid. In dogs, desogestrel is mainly metabolized at the C3- and C17-positions[1].

Protocol

Animal Research:

[1]

- Collapse
  • Animal Models: Female Wistar rats, Female beagle dogs
  • Formulation: gelatin (0.5%, w/v) and mannitol (5%, w/v)
  • Dosages: 56 μg/kg, 106 mg/kg (Rats); 67 μg/kg, 9.6 mg/kg(Dogs)
  • Administration: oral administration
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 62 mg/mL (199.69 mM)
Ethanol 62 mg/mL (199.69 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 310.47
Formula

C22H30O

CAS No. 54024-22-5
Storage powder
in solvent
Synonyms Cerazette, Desogen, Desogestrelum, Org-2969

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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