Citric acid

Catalog No.S5761

For research use only.

Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.

Citric acid Chemical Structure

CAS No. 77-92-9

Purity & Quality Control

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Biological Activity

Description Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 38 mg/mL
(197.79 mM)


* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 192.12
Formula

C6H8O7

CAS No. 77-92-9
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(C(=O)O)C(CC(=O)O)(C(=O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02919631 Unknown status Drug: Triheptanoin|Drug: Placebo oil Glycogen Storage Disease Type V Institut National de la Santé Et de la Recherche Médicale France|Rigshospitalet Denmark October 2016 Phase 2
NCT03007160 Unknown status Drug: Potassium Citrate Extended-release Tablets Urolithiasis Dawnrays Pharmaceutical (Holdings) Limited July 2016 Phase 4
NCT02476890 Completed Drug: Gefapixant 100 mg|Drug: Placebo Refractory Chronic Cough Afferent Pharmaceuticals Inc. October 28 2015 Phase 2
NCT02482818 Recruiting Drug: Pregabalin|Drug: Control-Placebo Cough Ottawa Hospital Research Institute September 2015 Phase 1|Phase 2

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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