(-)-Catechin gallate

Synonyms: (-)-CG

(-)-Catechin gallate ((-)-CG) is a catechin polyphenol that has been found in green tea extracts with diverse biological activities.

(-)-Catechin gallate Chemical Structure

(-)-Catechin gallate Chemical Structure

CAS: 130405-40-2

Purity & Quality Control

Batch: E023901 DMSO] 88 mg/mL] false] ] ] false] ] ] false Purity: 99.81%
99.81

(-)-Catechin gallate Related Products

Biological Activity

Description (-)-Catechin gallate ((-)-CG) is a catechin polyphenol that has been found in green tea extracts with diverse biological activities.
In vitro
In vitro

(-)-Catechin gallate is a minor polyphenolic constituent in green tea, which induces apoptosis of cells derived from tissues of the human oral cavity by the more specific TUNEL procedure.[1]

Cell Research Cell lines Immortalized epithelioid gingival S-G cells, salivary gland squamous carcinoma HSG cells, normal gingival HGF-1 fibroblasts, tongue squamous carcinoma CAL27 cells
Concentrations 50, 100, 150, 200 µM
Incubation Time 3 days
Method

Individual wells of a 96-well microtiter tissue culture plate are inoculated with 0.2 ml of the growth medium containing 2×10<sup>4</sup>cells/well for a 1-day exposure, 1.5×10<sup>4</sup>cells/ well for a 2-day exposure and 1×10<sup>4</sup>cells/well for a 3-day exposure to the test agents. After 1 day of incubation, the growth medium is removed and replaced with exposure medium, with or without varied concentrations of the test agents. In some studies the cells are coexposed to CG and 100 Units/ml catalase. After 1-3 days of exposure to the test agents, viability is assessed with the neutral red (NR) assay.

Chemical Information & Solubility

Molecular Weight 442.37 Formula

C22H18O10

CAS No. 130405-40-2 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 88 mg/mL ( (198.92 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy (-)-Catechin gallate | (-)-Catechin gallate supplier | purchase (-)-Catechin gallate | (-)-Catechin gallate cost | (-)-Catechin gallate manufacturer | order (-)-Catechin gallate | (-)-Catechin gallate distributor