CA-4948 S-Isomer
For research use only.
Catalog No.S9779
1 publication
CAS No. 1801344-14-8
CA-4948 S-Isomer is a potent and orally bioavailable inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with anti-tumor activity.
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Selleck's CA-4948 S-Isomer has been cited by 1 publication
Purity & Quality Control
Choose Selective IRAK Inhibitors
Biological Activity
| Description | CA-4948 S-Isomer is a potent and orally bioavailable inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with anti-tumor activity. |
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Protocol
References
Solubility (25°C)
Chemical Information
| Molecular Weight | |
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| Formula | |
| CAS No. | 1801344-14-8 |
| Storage |
powder in solvent |
| Synonyms | N/A |
In vivo Formulation Calculator (Clear solution)
| Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment) | ||||||||||
| Dosage | mg/kg |  |
Average weight of animals | g | |
Dosing volume per animal | ul | |
Number of animals | |
| Step 2: Enter the in vivo formulation () | ||||||||||
| % DMSO % % Tween 80 % ddH2O | ||||||||||
| CalculateReset | ||||||||||
Calculation results:
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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