research use only

Benzyl-α-GalNAc

Name: Benzyl-α-GalNAc
Brand: Selleck Chemicals
SKU: E8054
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.E8054

Benzyl-α-GalNAc is an inhibitor of O-glycosylation. It can be used in research to study antifibrotic strategies by decreasing α-SMA, collagen I/III, and hepatic stellate cells proliferation, and to enhance 5-Fluorouracil (5-FU) efficacy in pancreatic cancer by reducing mucin and overcoming drug resistance.

Chemical Structure

Molecular Weight: 311.33

Jump to Mechanism of Action Chemical Information, Storage & Stability

Quality Control

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Chemical Information, Storage & Stability

Molecular Weight	311.33	Formula	C₁₅H₂₁NO₆	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	3554-93-6	Download SDF Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References	[1] https://pubmed.ncbi.nlm.nih.gov/17912239/ [2] https://pubmed.ncbi.nlm.nih.gov/23743764/

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