CAS No. 3554-93-6
Batch:
Purity:98.34
Chemical Structure
Check the
Benzyl-α-GalNAc
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 3554-93-6 | |
|---|---|---|
| Molecular Formula |
C15H21NO6 |
|
| Molecular Weight (MW) | 311.33 |
Benzyl-α-GalNAc is a cell-permeable inhibitor of mucin-type O-glycosylation. By blocking O-glycan elongation, it impairs mucin biosynthesis and suppresses downstream cellular processes such as hepatic stellate cell proliferation and extracellular matrix deposition, including α-SMA and collagen I/III production. Furthermore, attenuation of mucin expression by Benzyl-α-GalNAc overcomes chemoresistance and enhances the therapeutic efficacy of 5-Fluorouracil in cancer models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
62 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 2 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.