CAS No. 58-64-0
Batch:
Purity:99.59
Chemical Structure
Check the
ADP
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate | |
|---|---|---|
| CAS Number | 58-64-0 | |
| Molecular Formula |
C10H15N5O10P2 |
|
| Molecular Weight (MW) | 427.20 | |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N | |
| InChIKey | XTWYTFMLZFPYCI-KQYNXXCUSA-N |
Biological Activity
ADP is an endogenous nucleotide and purinergic receptor agonist that activates P2Y1, P2Y12, and P2Y13 receptors. Extracellular binding of ADP to purinergic receptors stimulates intracellular calcium mobilization and inhibits adenylyl cyclase, driving platelet activation, shape change, and aggregation. In addition, ADP serves as a vital intermediate in cellular energy metabolism and mitochondrial ATP synthesis. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 43 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 85 mg/mL |
| DMSO |
6 mg/mL
(14.04 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
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Note: Technical data last updated: Sep 1, 2026.