Adenosine Cyclophosphate

Catalog No.S9370 Synonyms: Cyclic adenosine monophosphate, cAMP, cyclic AMP, 3',5'-cyclic adenosine monophosphate

For research use only.

Adenosine Cyclophosphate (Cyclic adenosine monophosphate, cAMP, cyclic AMP, 3',5'-cyclic adenosine monophosphate) is useful for improving myocardial hypoxia, dilating coronary artery and strengthening myocardiac contraction.

Adenosine Cyclophosphate Chemical Structure

CAS No. 60-92-4

Purity & Quality Control

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Biological Activity

Description Adenosine Cyclophosphate (Cyclic adenosine monophosphate, cAMP, cyclic AMP, 3',5'-cyclic adenosine monophosphate) is useful for improving myocardial hypoxia, dilating coronary artery and strengthening myocardiac contraction.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO Insoluble


* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 329.21
Formula

C10H12N5O6P

CAS No. 60-92-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(O1)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04945681 Not yet recruiting Biological: Pneumococcal conjugate vaccine Pneumococcal Infections London School of Hygiene and Tropical Medicine|Save the Children|Murdoch Children''s Research Institute|Ministry of Health Development Somaliland November 2021 Phase 4
NCT04921124 Completed Drug: Teriparatide Stress Fracture Norfolk and Norwich University Hospitals NHS Foundation Trust|University of East Anglia|Ministry of Defence United Kingdom May 24 2021 Phase 3
NCT04581629 Active not recruiting Drug: CLTX-305 Autosomal Dominant Hypocalcemia (ADH) Calcilytix Therapeutics Inc. a BridgeBio company September 15 2020 Phase 2
NCT04209179 Terminated Drug: PCO371|Drug: Placebo Hypoparathyroidism Chugai Pharmaceutical July 23 2020 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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