Taxifolin (Dihydroquercetin)

Catalog No.S2366

For research use only.

Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.

Taxifolin (Dihydroquercetin) Chemical Structure

CAS No. 480-18-2

Selleck's Taxifolin (Dihydroquercetin) has been cited by 3 Publications

Purity & Quality Control

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Biological Activity

Description Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
Targets
VEGFR2 kinase [4]
In vitro

Taxifolin is not mutagenic and low toxic compared to Qercetin. [1] It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism. [2] Taxifolin has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. [3]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 304.25
Formula

C15H12O7

CAS No. 480-18-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC(=C(C=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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