MG-132

Catalog No.S2619

MG-132 Chemical Structure

Molecular Weight(MW): 475.62

MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.

Size Price Stock Quantity  
USD 50 In stock
USD 170 In stock
USD 470 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Selleck's MG-132 had a noticeably greater effect when compared with similar products from Sigma: This is directly due to using the (S, R, S) - (-) - 2 configuration.

P21 protein can be degraded through ubiquitylation pathway. Inhibition of proteasome activities results in the accumulation of P21 protein, therefore, the more powerful the inhibiting effect, the more P21 protein is accumulated. (testing protein: P21; Cell line: Hela; treatment condition: final concentration of MG-132 is 5μM, with a 6 hour treatment time)

Cited by 48 Publications

11 Customer Reviews

  • Western blot of IκBζ expression in BMDMs treated with DI and stimulated with LPS for 1 h. MG132 or bafilomycin A (BafA) were added 30 min before LPS stimulation.

    Nature, 2018, 556(7702):501-504. MG-132 purchased from Selleck.

    MDA-MB-231 cells were treated with 10 uM MG132 and incubated under normoxia or hypoxia for 4 h. Endogenous interaction between LATS2 and SIAH2 was analysed by immunoprecipitation.

    Nat Cell Biol 2015 17(1), 95-103. MG-132 purchased from Selleck.

  • HeLa cells were transfected with control mimic, RMND5A siRNA or miR-138 mimic. After transfection for 36 h, cells were treated with proteasome inhibitor MG132 (20 uM) or Dimethyl sulfoxide (DMSO) for 8 h. Endogenous Exportin-5 protein and RMND5A protein expression was measured by western blotting.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

    HeLa cells were transfected with negative control mimic, miR-138 mimic or RMND5A siRNA. After transfection for 36 h, cells were treated with MG132 (20 uM) or DMSO for 8 h. RMND5A and Exportin-5 protein expression were analyzed by immunocytochemistry. Nuclei were counterstained with DAPI.

    Nucleic Acids Res 2014 42(1), 458-74. MG-132 purchased from Selleck.

  •  

    TFEB induced autophagy dependent ATZ clearance in vitro. MEF transiently co-transfected with either ATZ plus GFP expressing plasmids or ATZ plus TFEB expressing plasmids were incubated with proteasome inhibitor MG132 or with DMSO for 6 h. Upon MG132 treatment, steady state levels of 52 kDa ATZ band increased in both cells transfected with ATZ plus GFP and with ATZ plus TFEB expressing plasmids. Quantification of band intensities showed a 48% reduction of ATZ in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP, in the absence of the proteasome inhibitor. In MG132 treated cells, a 61% decrease of ATZ was detected in cells transfected with ATZ plus TFEB compared to cells transfected with ATZ plus GFP.

    EMBO Mol Med 2013 5, 397-412. MG-132 purchased from Selleck.

    JAK1 expression was analyzed in A375 cells expressing scrambled shRNA or shRNF125 (#2) and treated with MG132 (5 uM, 10 hr), and in Lu1205 cells expressing WT RNF125 and treated with MG132.

    Cell Rep 2015 11(9), 1458-73. MG-132 purchased from Selleck.

  • LRB1 and LRB2 regulate phyB protein levels. PhyB protein levels in crude extracts from the wild type (WT) and the indicated mutant backgrounds were assayed by immunoblot analysis with anti-phyB monoclonal antibodies. Anti-PBA1 and anti-histone H3 antibodies were used to confirm equal protein loading. Rc-induced loss of phyB in the wild type is inhibited by 100 uM MG132.

    Plant Physiol 2012 60(1), 118-34. MG-132 purchased from Selleck.

    Representative images for γ-H2AX-stained cells treated with 100 uM FA for 3 h without or with MG132. Fluorescence was measured in at least 50 nuclei in each of three experiments.

    Toxicol Appl Pharmacol 2015 286(2), 135-41. MG-132 purchased from Selleck.

  • Nek2A impedes SuFu ubiquitination. HEK293T cells transfected with Nek2A-Myc and Flag-SuFu for 48 h were treated with MG-132 to enrich ubiquitinated proteins, and subsequently subjected to co-immunoprecipitation assay. Precipitated proteins were probed using anti-Ub antibody.

    Int J Oncol, 2017, 50(2):373-380. MG-132 purchased from Selleck.

    GSK-3β phosphorylation at Ser9 is enhanced in NOK-overexpressed stable cell lines. The proteasome inhibitor, MG132, was added in medium of HeLa-HA and HeLa-NOK-HA cells for 12 h and then the p-GSK-3b(Ser9) was assayed by western blotting.

    FEBS Lett 2012 586, 3787–3792. MG-132 purchased from Selleck.

  • Truncated mouse Period2 (Per2) protein was expressed in NIH3T3 cells, treated by cycloheximide with or without MG132 for 1-4 hours.Per2 was reported to be degraded by the proteasome proteolysis. By adding MG132 (25 μM), a proteasome inhibitor, the degradation of Per2 was dramatically decreased within 4 hours treatment (shown by western blot).

    2012 Dr. Edison DUKE-NUS Graduate Medical School Singapore.. MG-132 purchased from Selleck.

Purity & Quality Control

Choose Selective Proteasome Inhibitors

Biological Activity

Description MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50s of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.
Targets
20S proteasome [9]
(Cell-free assay)
100 nM
In vitro

MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM. MG-132 also inhibits calpain with IC50 of 1.2 μM. MG-132 induces neurite outgrowth in PC12 cells at an optimal concentration of 20 nM, displaying 500 times more potency than ZLLal. [1] MG-132 (10 μM) potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. [2] MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition. [3] Unlike BzLLLCOCHO or PS-341, MG-132 treatment results in weak inhibition of the chymotrypsinlike (CT-L) and peptidylglutamyl peptide hydrolysing (PGPH) activities of the 26S proteasome, whereas multiple myeloma cells (U266 and OPM-2) are more sensitive to induction of apoptosis by MG-132 than BzLLLCOCHO. [4] MG-132 (1 μM) sensitizes TRAIL-resistant prostate cancer cells by activating the AP-1 family members c-Fos and c-Jun, which, in turn, repress the antiapoptotic molecule c-FLIP(L). [5] MG-132 significantly enhances the ability of inositol hexakisphosphate (IP6) to reduce cellular metabolic activity in both PC3 and DU145 androgen-independent prostate cancer (AIPCa) cell lines. [6]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
LPS-stimulated RAW264.7 cells NIPNOZZHfW6ldHnvckBCe3OjeR?= M{DCU|I2KM7:TR?= MVjEUXNQ M1XIfGlvcGmkaYTzJI5qfHKrYzDvfIll\SCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAxNjFizszN MofsNlQ3QTd2OU[=
HL-60 NVL6[IJOS3m2b4TvfIlkKEG|c3H5 MmPpOFAh|ryP NFTzfHM1QCCq NFPpUFBFVVOR M33ES2lEPTB:MUCg{txO NIHMc4ozPDZ7N{S5Oi=>
SMMC-7721 NYTK[I1qS3m2b4TvfIlkKEG|c3H5 MnXmOFAh|ryP NV74c25NPDhiaB?= MVLEUXNQ NGHWdodKSzVyPUeuNUDPxE1? M2f0T|I1Pjl5NEm2
A-549 M1S1NWN6fG:2b4jpZ{BCe3OjeR?= NEPIdFc1OCEQvF2= MXG0PEBp MXTEUXNQ NHjMXHNKSzVyPEGwJO69VQ>? MUeyOFY6PzR7Nh?=
MCF-7 MVLDfZRwfG:6aXOgRZN{[Xl? NYDk[YZHPDBizszN M{foTVQ5KGh? NWD6Z5BrTE2VTx?= M3HLZWlEPTB;Nz6zJO69VQ>? Mn22NlQ3QTd2OU[=
SW-480 NGLCeHBEgXSxdH;4bYMhSXO|YYm= NF23PHg1OCEQvF2= M{DlUFQ5KGh? NYLoeZpqTE2VTx?= MnnuTWM2OD12IN88US=> MlLvNlQ3QTd2OU[=
NCI-H929 NEi5bWlEgXSxdH;4bYMhSXO|YYm= MX[xJO69VQ>? NX[0T5d4PzJiaB?= M{XxXWROW09? NXvl[VBYUUN3ME2wMlE4KM7:TR?= Ml3BNlQ3OjVyOEi=
293T MWPDfZRwfG:6aXOgRZN{[Xl? NHLXUXMyOCEQvF2= Ml7uO|IhcA>? M2Pp[GROW09? MoPFTWM2ODx{IN88US=> M{G0O|I1PjJ3MEi4
293T M1\aUWZ2dmO2aX;uJGF{e2G7 MnjZNVAh|ryP NULr[HR[OjRiaB?= M3LwXWROW09? NGrySlZOd2SncnH0[Yx6KGmwZIXj[ZMhcGWjdD3zbI9kcyBi NHrlPGMzPDZ{NUC4PC=>
HeLa MU\LbY5ie2ViQYPzZZk> Ml;WNVAh|ryP MXSxJIg> NYm4[ItJTE2VTx?= MUPJcoR2[2W|IGDBVnAh[2ynYY\h[4Uh[nliaX7obYJqfGmwZzDwdo9{\WG|b33lJIFkfGm4aYT5 NULUbYhzOjR|MkG4N|M>
MDA-MB-231 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGnjV5oyKM7:TR?= NGPaO|c4OiCq M2D5bmROW09? NEmyPJVKSzVyPUCuNVgh|ryP MXKyOFE2OzJyNh?=
MCF-7 Ml3LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH;KbZoyKM7:TR?= M4rrbFczKGh? MlP5SG1UVw>? M2\YfWlEPTB;MD6xN{DPxE1? NIX5XFIzPDF3M{KwOi=>
MCF10A NHO0dFVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVTJPY1GOSEQvF2= M3LyS|czKGh? MnvWSG1UVw>? NHXM[mZKSzVyPUCuNlkh|ryP M{fQOlI1OTV|MkC2
HEK-293 NGmyRmtMcW6jc3WgRZN{[Xl? Mmn0NkBidmRiMkCg{txO NYfjfpJlOiCq NF[1d|RFVVOR MlzBTY5pcWKrdIOgR4hVNUxiYXP0bZZqfHlid3n0bEBKSzVyIH;mJFkhdk1i NUPz[m5ROjN3NEC3PVA>
Calu6 MULGeY5kfGmxbjDBd5NigQ>? NX3KWXhDOTBizszN M2XyNlE5KGh? MkD2SG1UVw>? NFr0PYhUcWewaX\pZ4FvfGy7IHHjZ5VufWyjdHXzJIZz[XSjeHnuJJBz\WO3coPvdi=> MXmyN|UxPjR6Nh?=
IFN-gamma-induced RAW264.7 MoDMSpVv[3Srb36gRZN{[Xl? Mn\hSG1UVw>? NGTpTGVKdmirYnn0d{BvcXS{aXOgc5hq\GVicILv[JVkfGmxbjD3bZRpKEmFNUCgc4YhOC5yN{eg{txO M3PkR|IzOjd5Mke3
IPC227F NX33V4xjS3m2b4TvfIlkKEG|c3H5 M1;yNFEh|ryP NU\KV2pTPDhiaB?= NXK3e4xbTE2VTx?= M2XNW2lEPTB;MD6wO|ch|ryP NWfo[YExOjF7MkS1Nlg>
Hepa-1c1c7 MWXGeY5kfGmxbjDBd5NigQ>? NVjDXGRsOjVizszN MmLQOkBp M3jITGROW09? NWGxPJhKUW6lcnXhd4V{KE6{ZkKgdJJwfGWrbjDs[ZZmdA>? M1rxXlIxOzl{NUS0
COS-7 MoK5R5l1d3SxeHnjJGF{e2G7 NXL6cZRDOTBizszN MYfEUXNQ MYjJR|UxRDFyIN88US=> M1\LS|E5ODh6MEm3
HuH-7 M1\ESmN6fG:2b4jpZ{BCe3OjeR?= M{jZcVExKM7:TR?= NVfKOVhtTE2VTx?= NXyzXVhKUUN3MEyxNEDPxE1? MkDqNVgxQDhyOUe=
OCI-Ly3 M13xTmZ2dmO2aX;uJGF{e2G7 MUCxNEDPxE4EoB?= NHzWZmw1KGh? M4XEUGROW09? NXXkVGY5UW6mdXPld{BpfW2jbjDJb4FxeGGEYXzwbIEhe3SjYnnsbZpifGmxbjD3bZRpKEWFNUCgc4YhOSEQvF2= NIf3ZVkyQDB{NEGxNy=>
A2780 cDDP NILsb2ZCeG:ydH;zbZMhSXO|YYm= MVGyOEBp M2TkTWROW09? NVz4Tnp{UW6mdXPld{BieG:ydH;zbZMh[nliaX7obYJqfGmwZzDQWGVPKGSnZ4Lh[IF1cW:w MVGxO|Y5PDBzOB?=
LPS-stimulated RAW264.7 cells NH\6cmNHfW6ldHnvckBCe3OjeR?= MWXEUXNQ NVG0eHp2UW6qaXLpeJMhVkZva3HwdIFDKESQQTDibY5lcW6p NGnTR20yPzRyN{K3Oy=>
PC12 MVXGeY5kfGmxbjDBd5NigQ>? MUexNFAh|ryPwrC= M{fiT|I1KGh? NIWySpZFVVOR MUDJcohq[mm2czC2MW9JTEFvIHHu[EBJOk9{LXnu[JVk\WRiY4n0c5RwgGmlaYT5 NVvJepl3OTdzNUi0OVQ>
PC3 NHXlcpNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYmyNEDPxE1? NWDabYZqPDhiaB?= NHq0VnJFVVOR MkPnTWM2OD1yLk[g{txO NX;CWXptOTZ4OE[1N|c>
LP-1 MYXBdI9xfG:|aYOgRZN{[Xl? NVLHU|JkOzByIH7N M3vOPVI1KGh? MYTEUXNQ M2rYb2lv\HWlZYOgZZBweHSxc3nzJIJ6KGmwY4LlZZNqdmdiY3zlZZZm\CCSQWLQJIxmfmWuIHHu[EBz\WS3Y3nu[{BO[2xvMTDwdo91\WmwIHzleoVt M1jI[lE2QTV6NUi5
ES6 NIGzO|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3G4dWlEPTB;MD6wNVMxPiEQvF2= M1HqbnNCVkeHUh?=
A101D M2j3eGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjYT2dKSzVyPUCuNFMzPzlizszN NIjqbJNUSU6JRWK=
OCUB-M M2TGZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELBTIdKSzVyPUCuNFM4OzdizszN M{XoTXNCVkeHUh?=
LB2518-MEL MofRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlKyTWM2OD1yLkCzO|Yh|ryP NHfuT|lUSU6JRWK=
SH-4 NV3lWlA2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nrPWlEPTB;MD6wOFMyKM7:TR?= MlzaV2FPT0WU
KNS-42 NIfQcWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3jzOWlEPTB;MD6wOFQ1OSEQvF2= NFO0OGxUSU6JRWK=
DSH1 NF3YZW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MljnTWM2OD1yLkC1Nlg6KM7:TR?= NWfEZmRbW0GQR1XS
NTERA-S-cl-D1 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXT1c2g5UUN3ME2wMlA2Pzd{IN88US=> MYDTRW5ITVJ?
D-542MG MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\KTWM2OD1yLkC1PVU4KM7:TR?= MlmyV2FPT0WU
KS-1 NV:0Z2dkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mk\lTWM2OD1yLkC2OFU5KM7:TR?= MXTTRW5ITVJ?
BL-41 MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1\HZmlEPTB;MD6wOlk1PyEQvF2= M3O4XHNCVkeHUh?=
LXF-289 M1vxVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVTnRVV3UUN3ME2wMlA4ODZ4IN88US=> M{XkcHNCVkeHUh?=
D-247MG NGnjWo9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlGxTWM2OD1yLkC3NlA6KM7:TR?= MkX6V2FPT0WU
MMAC-SF MnjsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{PhXmlEPTB;MD6wO|I3QCEQvF2= NHvjWWlUSU6JRWK=
CP66-MEL NEPlW2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUf1WWpIUUN3ME2wMlA4PSEQvF2= M2PWdnNCVkeHUh?=
LB771-HNC NGrPZmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVfOOm14UUN3ME2wMlA5ODN4IN88US=> NWDje4M4W0GQR1XS
no-10 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4jF[2lEPTB;MD6wPFkxQSEQvF2= M{fKNXNCVkeHUh?=
A388 NXXxUZpiT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2\rdWlEPTB;MD6wPVA3PSEQvF2= M3rX[3NCVkeHUh?=
OPM-2 MoHHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1XsdmlEPTB;MD6xNFQ4PCEQvF2= NX3qb|BNW0GQR1XS
OVCAR-4 MlrKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUDJR|UxRTBwMUC5N|gh|ryP MX\TRW5ITVJ?
HOP-62 M4rabWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVnJR|UxRTBwMUC5OFkh|ryP NGDV[YRUSU6JRWK=
ML-2 MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M32wNmlEPTB;MD6xNVgxPiEQvF2= MUHTRW5ITVJ?
UACC-257 M1\weGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEHIcVFKSzVyPUCuNVE6OjdizszN MoLlV2FPT0WU
NEC8 Mo\SS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1rodWlEPTB;MD6xNVk6PSEQvF2= NX2zTW45W0GQR1XS
ONS-76 NXTpO5pWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mnv4TWM2OD1yLkGyPVM2KM7:TR?= M4XzfXNCVkeHUh?=
KE-37 NV;YRXFIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml7LTWM2OD1yLkGzNlc5KM7:TR?= M4XIdnNCVkeHUh?=
HT-144 NHXTfmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\TXIVKSzVyPUCuNVM5QTVizszN NGPFXIFUSU6JRWK=
LB2241-RCC NGrj[INIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nVe2lEPTB;MD6xOFI1PyEQvF2= MkjrV2FPT0WU
TE-5 NEXqfIpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFrjR|BKSzVyPUCuNVQzPzhizszN MoDKV2FPT0WU
KINGS-1 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGHRblBKSzVyPUCuNVQ4QSEQvF2= MWHTRW5ITVJ?
NCI-H69 MlzQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{HWbGlEPTB;MD6xOVE1OSEQvF2= M3rRfHNCVkeHUh?=
CAS-1 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF;TOYdKSzVyPUCuNVU1QDJizszN MVnTRW5ITVJ?
D-263MG MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYr2OpNTUUN3ME2wMlE3ODB4IN88US=> NUL3V44xW0GQR1XS
A253 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTBwMU[xNlgh|ryP NEHEcGFUSU6JRWK=
PF-382 MoXsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV\2[ZFxUUN3ME2wMlE3PzB4IN88US=> NG\SNHBUSU6JRWK=
CESS NHzKcY5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NY\4NJFmUUN3ME2wMlE4ODZizszN NIS3Z2JUSU6JRWK=
MZ2-MEL M1G4dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX7iXHNPUUN3ME2wMlE4PTV7IN88US=> NVfEUVFTW0GQR1XS
HEL MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULvUGJNUUN3ME2wMlE5PTF5IN88US=> NV7yOYtPW0GQR1XS
D-392MG NUDNeo5vT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3XIZWlEPTB;MD6xPVEyPSEQvF2= NXvNflBbW0GQR1XS
SK-LMS-1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1XvWmlEPTB;MD6xPVMxOyEQvF2= NW\kS3dkW0GQR1XS
GI-ME-N M3PXOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxRTBwMUmzNFYh|ryP NIDFVZdUSU6JRWK=
LB831-BLC M{fHd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFvsN3pKSzVyPUCuNVk{PCEQvF2= M3ToWHNCVkeHUh?=
DU-4475 Mo\kS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXXtZ3VWUUN3ME2wMlE6PjV6IN88US=> MWrTRW5ITVJ?
IST-SL1 MoPqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkfNTWM2OD1yLkKwNFk1KM7:TR?= M1TkVXNCVkeHUh?=
GAK M3P1c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmDVTWM2OD1yLkKwOVM1KM7:TR?= MlznV2FPT0WU
EW-1 MlfyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjZRXpKSzVyPUCuNlExPDdizszN MojQV2FPT0WU
LAMA-84 MlfDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2rZe2lEPTB;MD6yNVg2OSEQvF2= NEO1WmtUSU6JRWK=
SK-UT-1 MnmwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEe1XYFKSzVyPUCuNlIxPDlizszN NGe0S4dUSU6JRWK=
VA-ES-BJ MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXTJR|UxRTBwMkKyOVch|ryP M3\uNHNCVkeHUh?=
ACN MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\UTWM2OD1yLkKyOlM5KM7:TR?= NVLMTIEyW0GQR1XS
SK-PN-DW Mlj0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1fyNmlEPTB;MD6yN|E6KM7:TR?= M2roW3NCVkeHUh?=
HD-MY-Z NY\P[ZNJT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHGUItkUUN3ME2wMlI{OzB|IN88US=> NFX0V|RUSU6JRWK=
LB373-MEL-D MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M121ZmlEPTB;MD6yOFE6QCEQvF2= NIfzcplUSU6JRWK=
COLO-829 M176WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mny2TWM2OD1yLkK0NlU4KM7:TR?= MlzEV2FPT0WU
ES8 MW\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mo\lTWM2OD1yLkK0O|Y{KM7:TR?= MlKzV2FPT0WU
RXF393 MkPTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUPEWWlGUUN3ME2wMlI2ODF3IN88US=> M2T3TnNCVkeHUh?=
TK10 NH3qRppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2nVfWlEPTB;MD6yOVQ{PSEQvF2= MnP1V2FPT0WU
LOUCY MnvsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXjlW4pQUUN3ME2wMlI2PDV4IN88US=> NYHXPIxzW0GQR1XS
MZ7-mel MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUTJR|UxRTBwMk[zO|Qh|ryP NEDlV2xUSU6JRWK=
CP67-MEL MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoG3TWM2OD1yLkK2O|Mh|ryP M2\hb3NCVkeHUh?=
C2BBe1 M33Yemdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUfJR|UxRTBwMke5NFch|ryP MWnTRW5ITVJ?
K052 NGLTfVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2jxd2lEPTB;MD6yPFk6KM7:TR?= NE\PNoNUSU6JRWK=
MOLT-16 NVzqXZd5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWLJR|UxRTBwMkm1NlQh|ryP MX\TRW5ITVJ?
KNS-81-FD M3izW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWewfJBLUUN3ME2wMlMxOzJ|IN88US=> MWHTRW5ITVJ?
CMK M{e4dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmrxTWM2OD1yLkOxNVIh|ryP NXXwXZhyW0GQR1XS
LAN-6 M1;KVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYntdlVSUUN3ME2wMlMyOyEQvF2= NF3jXY5USU6JRWK=
KLE NXnMVo5kT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH20dI9KSzVyPUCuN|E{ODZizszN NFj6bm1USU6JRWK=
NCCIT MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXXJR|UxRTBwM{G3PFMh|ryP NEGyepVUSU6JRWK=
HH M{S4fWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2f6Z2lEPTB;MD6zNlg6PyEQvF2= MkDIV2FPT0WU
TE-8 MnvtS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn62TWM2OD1yLkO0Nlc6KM7:TR?= MmHVV2FPT0WU
GDM-1 NH;neYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPJTWM2OD1yLkO1NVA1KM7:TR?= NWnsR5EyW0GQR1XS
NCI-H747 MYLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxRTBwM{exNFMh|ryP MU\TRW5ITVJ?
NCI-H1092 MoLLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmn3TWM2OD1yLkO4PFQ1KM7:TR?= NF3kcHBUSU6JRWK=
8-MG-BA NF;vUYZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2\nfmlEPTB;MD6zPVg{PyEQvF2= Mnf6V2FPT0WU
NB17 NGHiclBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MWjJR|UxRTBwNEK5O{DPxE1? MojwV2FPT0WU
LC4-1 NV7UPGkyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV7JR|UxRTBwNEO2NFch|ryP NXT4VZF2W0GQR1XS
TE-1 M2PSTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYnwb2RIUUN3ME2wMlQ2OTF7IN88US=> NXrFOJZQW0GQR1XS
KALS-1 NIHudYFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDCUWVKSzVyPUCuOFY2QDRizszN NFyzN5JUSU6JRWK=
CCRF-CEM NVTqcHJ4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1fpeWlEPTB;MD60O|Y4PCEQvF2= MkLoV2FPT0WU
OS-RC-2 NITseW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4HhRWlEPTB;MD60O|k4OiEQvF2= NVP5cFdwW0GQR1XS
A704 NVvXT4ZKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV;sSodsUUN3ME2wMlQ5Pjl{IN88US=> Ml30V2FPT0WU
BB49-HNC M2DmWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2nu[WlEPTB;MD60PVA6PiEQvF2= NVO5V2RZW0GQR1XS
EVSA-T NX\URmlVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTBwNEm5NVEh|ryP M2jMbnNCVkeHUh?=
Mo-T NY[yUlIzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlfPTWM2OD1yLkWxO|YzKM7:TR?= MVHTRW5ITVJ?
MONO-MAC-6 M4ewZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3SwNGlEPTB;MD61N|YyOSEQvF2= NIrOSXBUSU6JRWK=
BB65-RCC MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTjNIxxUUN3ME2wMlU3QDFzIN88US=> M3;MTnNCVkeHUh?=
NCI-H1882 NIO5V|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEPYRVZKSzVyPUCuOVkxOzZizszN NELFZZBUSU6JRWK=
TE-9 M1TYS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGD1UHlKSzVyPUCuOlExOzNizszN M1LOenNCVkeHUh?=
NCI-H2126 M2L5V2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NH7COY1KSzVyPUCuOlI3PjlizszN MVTTRW5ITVJ?
SF268 M17tXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mk\YTWM2OD1yLk[1OlQyKM7:TR?= NFj1SIVUSU6JRWK=
SW872 MnvjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoH0TWM2OD1yLk[1O|I6KM7:TR?= MV;TRW5ITVJ?
LS-513 MlLDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NW\vVXd1UUN3ME2wMlY3PzVzIN88US=> M2\Ub3NCVkeHUh?=
NCI-H1355 MVTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M33QS2lEPTB;MD62PFYyQSEQvF2= NVi5OnVEW0GQR1XS
BL-70 M4TJSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkmwTWM2OD1yLk[5N|g5KM7:TR?= MV7TRW5ITVJ?
NCI-SNU-5 M{joXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\CW3VKSzVyPUCuOlk2PDVizszN NYHlWYg{W0GQR1XS
SNU-C2B MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHLMfZdKSzVyPUCuO|A4OzlizszN M1[1WHNCVkeHUh?=
GB-1 MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWTYOY05UUN3ME2wMlczOTJ2IN88US=> MWrTRW5ITVJ?
CTB-1 NHW5XGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2SwNWlEPTB;MD63O|k2PSEQvF2= MUDTRW5ITVJ?
Becker NH;MV|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnPzTWM2OD1yLke5OlIyKM7:TR?= M1H6RXNCVkeHUh?=
KM12 NEf0TVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGjpXohKSzVyPUCuPFU1PjZizszN MoLBV2FPT0WU
ES7 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTBwOEm2OUDPxE1? MWjTRW5ITVJ?
COLO-684 NG[2boFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXrJR|UxRTBwOUC2OVgh|ryP MlTHV2FPT0WU
HCC2998 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnjQTWM2OD1yLkmzPFU1KM7:TR?= MmHsV2FPT0WU
TE-10 NUfN[FZqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUn1N3RWUUN3ME2wMlk3PDNizszN MUXTRW5ITVJ?
SF126 NGfve4xIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVHJR|UxRTBwOUi5O|Eh|ryP NFrZSphUSU6JRWK=
EKVX NWnmNZpvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXizZpRbUUN3ME2xMlA{PDR{IN88US=> MYfTRW5ITVJ?
KARPAS-45 MoXwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYTJR|UxRTFwMESwNVYh|ryP MYTTRW5ITVJ?
KGN NW\Ed2NnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\lTWM2OD1zLkC1NFQ2KM7:TR?= MULTRW5ITVJ?
ES1 MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYTXV|dEUUN3ME2xMlA4QTJzIN88US=> NUnTU5BsW0GQR1XS
L-540 M4K1W2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI[4bXhKSzVyPUGuNVE5OzlizszN M1XRV3NCVkeHUh?=
KURAMOCHI MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGjsRYlKSzVyPUGuNVI{PzRizszN NHHLN3FUSU6JRWK=
LU-65 M4f4cWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXBTWM2OD1zLkGyO|U{KM7:TR?= M3\a[nNCVkeHUh?=
MFH-ino M4\G[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3LhdmlEPTB;MT6xO|UxOSEQvF2= M2Xk[XNCVkeHUh?=
NCI-H23 NXzPTmp7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LMOWlEPTB;MT6yNFQyKM7:TR?= NFfMblNUSU6JRWK=
IA-LM Mn24S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHjXUXlKSzVyPUGuNlQyOTZizszN M2nDd3NCVkeHUh?=
PSN1 M133c2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoDMTWM2OD1zLkK3NFE3KM7:TR?= M3jGW3NCVkeHUh?=
NCI-H719 M4fQZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYThfnNVUUN3ME2xMlI4PDFzIN88US=> NFzZ[4RUSU6JRWK=
SW684 MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3LveWlEPTB;MT6yPFY2QSEQvF2= M3fqfnNCVkeHUh?=
HCE-4 NVnhWVM1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVO5flNYUUN3ME2xMlMxOjJzIN88US=> MVjTRW5ITVJ?
EW-16 NF;idmJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFfhfoNKSzVyPUGuN|E{PDdizszN Moq4V2FPT0WU
NCI-H128 MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmTrTWM2OD1zLkO1PFE1KM7:TR?= NETUNmpUSU6JRWK=
HC-1 NX;0TItWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWPLVWxrUUN3ME2xMlM5OTdizszN MWPTRW5ITVJ?
IST-MES1 M2e1U2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWnzbWZ5UUN3ME2xMlQxOjB6IN88US=> M3\xd3NCVkeHUh?=
Raji MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nMWGlEPTB;MT60NVg2KM7:TR?= MVHTRW5ITVJ?
DMS-114 M1HIVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XzVWlEPTB;MT60OFU{QSEQvF2= M{XUXXNCVkeHUh?=
GI-1 NXPudFQ{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXCO2R6UUN3ME2xMlQ4OTNzIN88US=> NELicY9USU6JRWK=
NCI-H2081 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXvJR|UxRTFwNUWxPVYh|ryP MYnTRW5ITVJ?
LC-1F M4\MNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYjJR|UxRTFwNUWxPVgh|ryP MljvV2FPT0WU
NCI-H2227 MnnXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn:5TWM2OD1zLk[xOVYyKM7:TR?= MWXTRW5ITVJ?
D-502MG NGLSb3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4TkSWlEPTB;MT62O|IyOSEQvF2= NETaOXhUSU6JRWK=
NCI-H2141 NYSxdWNzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmjKTWM2OD1zLk[3N|E4KM7:TR?= MYPTRW5ITVJ?
LS-411N M4\hPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jSbGlEPTB;MT62PVgxPyEQvF2= MnWwV2FPT0WU
SU-DHL-1 Ml21S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnLwTWM2OD1zLkexNlgyKM7:TR?= M4j0fnNCVkeHUh?=
BB30-HNC NYHtNoF6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYnJR|UxRTFwN{K2PFUh|ryP MVfTRW5ITVJ?
TE-15 NYC4V4RuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTFwOUKzO|Mh|ryP MV;TRW5ITVJ?
JVM-3 NFP2OXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlGzTWM2OD1zLkmzPVA1KM7:TR?= M2OyNXNCVkeHUh?=
IST-SL2 NGnsSVRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHfQT|lKSzVyPUKuNFEzPTJizszN MWPTRW5ITVJ?
EW-18 NV36R3l[T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGf2dnJKSzVyPUKuNFI{OzdizszN M2LscXNCVkeHUh?=
DJM-1 MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4nwTmlEPTB;Mj6wNlU2OiEQvF2= M4XPOHNCVkeHUh?=
no-11 M2jvTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2D0WmlEPTB;Mj6wN|ExPCEQvF2= MYTTRW5ITVJ?
QIMR-WIL M{Pqd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYXJR|UxRTJwMU[3OlIh|ryP M{CxTXNCVkeHUh?=
MC-CAR MmPDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGnVcmJKSzVyPUKuNlI6PSEQvF2= M3PkOXNCVkeHUh?=
KM-H2 NEH1ZWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2TnO2lEPTB;Mj6yPVA1OyEQvF2= NWLmfmxXW0GQR1XS
ECC12 NWLncpliT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEnES3RKSzVyPUKuN|c6PCEQvF2= MlHNV2FPT0WU
HCE-T M3u2PWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PVVWlEPTB;Mj60OFg5OyEQvF2= MX\TRW5ITVJ?
MFM-223 MlfBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MnnkTWM2OD1{LkWwPFcyKM7:TR?= NFf3SplUSU6JRWK=
SW982 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HGd2lEPTB;Mj61NVQ5KM7:TR?= NULVdGx{W0GQR1XS
KG-1 NETRbHdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVPaenRDUUN3ME2yMlg5PzlzIN88US=> M2DvcHNCVkeHUh?=
ES4 MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV74dIN{UUN3ME2zMlA3OTFzIN88US=> M3rifnNCVkeHUh?=
SCC-3 NXy3O|lsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrlTWM2OD1|LkGwPFQ5KM7:TR?= M3XDbHNCVkeHUh?=
RH-1 MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlu4TWM2OD1|LkO4O|Q5KM7:TR?= NIjzXmlUSU6JRWK=
NCI-H748 NYTBRnNxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFflWXdKSzVyPUOuOFQzPjZizszN NHK5dZVUSU6JRWK=
HCC2218 MnHBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlTFTWM2OD1|LkS2PVM4KM7:TR?= NIOxfm5USU6JRWK=
MEG-01 M2[zTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUPJR|UxRTNwNUm2PEDPxE1? NVvVbIFpW0GQR1XS
NB12 NXjnV2NWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHTDXYJKSzVyPUOuOVk5QDhizszN MUnTRW5ITVJ?
SNB75 MWPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYPhc2w2UUN3ME2zMlYxOTB|IN88US=> MYXTRW5ITVJ?
KMS-12-PE NWHFVo5GT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnjHTWM2OD1|Lk[3O|I{KM7:TR?= M3jUdXNCVkeHUh?=
SKM-1 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVvJR|UxRTNwN{GzO|Yh|ryP MVnTRW5ITVJ?
COLO-320-HSR NGnFOW1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUnJR|UxRTNwN{W2N|Qh|ryP NY[5NGE3W0GQR1XS
NKM-1 M{PHbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfJeWNKSzVyPUOuO|c{PzhizszN MnfjV2FPT0WU
TE-6 MoLPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnNT3JOUUN3ME2zMlk1PTZzIN88US=> NV7hRndHW0GQR1XS
D-336MG MoHFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVPJSohLUUN3ME20MlAyOTZ4IN88US=> MXHTRW5ITVJ?
NCI-H1650 MlPHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX3TblVwUUN3ME20MlE2Pzl5IN88US=> NFuxcIpUSU6JRWK=
ES3 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWTJR|UxRTRwM{K4NlQh|ryP MXPTRW5ITVJ?
YT M1:2WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NV:3fVZ[UUN3ME20MlM2PDJ2IN88US=> MoXDV2FPT0WU
ES5 NXzxcmNMT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1LlXWlEPTB;ND60NFI2PSEQvF2= MnKzV2FPT0WU
LB647-SCLC MlXSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrJR|UxRTRwNU[zNFgh|ryP MYDTRW5ITVJ?
HAL-01 NFvwU4NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml\VTWM2OD12LkW3NFM1KM7:TR?= NXrLSHF1W0GQR1XS
LP-1 NH7H[GhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTRwN{KzO|Eh|ryP NWrv[5NLW0GQR1XS
BC-1 NHPpNXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXrie|hrUUN3ME21MlAxPDR5IN88US=> M1XZRXNCVkeHUh?=
EB-3 M3uyOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkOyTWM2OD13LkCzNFQyKM7:TR?= NWHXVW9DW0GQR1XS
GT3TKB MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVrJR|UxRTVwMUe2OlIh|ryP NH7DWldUSU6JRWK=
NCI-H209 NYO2c2tpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nrV2lEPTB;NT6xPVM2OiEQvF2= NVzPTJdrW0GQR1XS
BT-474 M1HKO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NILoO4NKSzVyPUWuNlMyODJizszN MVXTRW5ITVJ?
RKO NEDqO3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2XPR2lEPTB;NT6yN|QzOiEQvF2= NVjqV5d1W0GQR1XS
SIMA NF61[phIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEDGPVhKSzVyPUWuN|A4PjVizszN MoPnV2FPT0WU
RL MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUXC[ot[UUN3ME21MlM4PTRzIN88US=> NXzHXIxrW0GQR1XS
GCIY MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoHITWM2OD13LkS3NlM3KM7:TR?= M{Ph[nNCVkeHUh?=
Calu-6 M4rZVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXzJR|UxRTVwNkKyJO69VQ>? NXy5boNiW0GQR1XS
ALL-PO M2nXO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFPuPZdKSzVyPUWuOlM4QTVizszN MV7TRW5ITVJ?
ARH-77 MlOzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWjJR|UxRTVwNkewPFch|ryP NIPzVHdUSU6JRWK=
A4-Fuk NX;tdVhVT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\ITWM2OD14LkC4NVE5KM7:TR?= MkPnV2FPT0WU
NCI-H1581 Mle2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFfTfVVKSzVyPU[uNlM5PDlizszN NIPRXVlUSU6JRWK=
HUTU-80 NFTNb2FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4\XN2lEPTB;Nj6zOlg6PyEQvF2= NH20U5ZUSU6JRWK=
TGW NYPHW29FT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVv3fIl3UUN3ME22MlQ2PTl|IN88US=> M4nsUXNCVkeHUh?=
SK-N-FI NWLsV2VsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmH4TWM2OD14LkS1PFU1KM7:TR?= NGLzXmZUSU6JRWK=
U-266 NGrqUo1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;lfFFKSzVyPU[uOVE6OjZizszN NYnHfGlHW0GQR1XS
EM-2 M2GySWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmfWTWM2OD14Lk[3NFk6KM7:TR?= NYr2ZmhFW0GQR1XS
NMC-G1 NWXEOGZET3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{[xWmlEPTB;Nj63NVg6PSEQvF2= NUfpWlcxW0GQR1XS
KASUMI-1 NVjkZlNCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWHsc403UUN3ME22Mlg1Pzh5IN88US=> NWfKZotNW0GQR1XS
NALM-6 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVHYfWJpUUN3ME22Mlg3PzV2IN88US=> NH3iXlVUSU6JRWK=
OCI-AML2 NUjJVGJuT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3HXTmlEPTB;Nz6wNFMzPiEQvF2= NHf2SWxUSU6JRWK=
SHP-77 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFnGXWdKSzVyPUeuNlI1OyEQvF2= Ml21V2FPT0WU
NOMO-1 Mn;QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmTKTWM2OD15LkK0NlU1KM7:TR?= NWi5foxZW0GQR1XS
SK-N-DZ NYC2[25LT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYjJR|UxRTdwN{GwPFkh|ryP M3n2O3NCVkeHUh?=
LB1047-RCC NYf5V2Z2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2OzRWlEPTB;Nz63NlI{OSEQvF2= M{PSV3NCVkeHUh?=
MZ1-PC NVTPcnV{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTdwOE[1OVgh|ryP MlPYV2FPT0WU
NB10 M{LiW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mne2TWM2OD15Lkm5OVU3KM7:TR?= MVnTRW5ITVJ?
RL95-2 NHHvUHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYPJR|UxRThwMUC4OFIh|ryP M3rpcXNCVkeHUh?=
OMC-1 NXH4c5dnT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUPxXGNOUUN3ME24MlUzOTlzIN88US=> NGDBOnNUSU6JRWK=
D-283MED MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NF70cZhKSzVyPUiuPVE4OTlizszN MV3TRW5ITVJ?
MC116 NGmybJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWfVcFRVUUN3ME24Mlk4QTRizszN MULTRW5ITVJ?
SJSA-1 M2HKNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHfQNoZKSzVyPUmuNFkxQTFizszN NF:xbWRUSU6JRWK=
JiyoyeP-2003 M2Hwb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1O1N2lEPTB;OT6yPVMyPyEQvF2= NWT6SnZwW0GQR1XS
IST-MEL1 M33obmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoTsTWM2OD17Lke0NVk5KM7:TR?= M2Xxe3NCVkeHUh?=
CTV-1 NVTvWnhHT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXKwdI5sUUN3ME2xNE4xQTd7IN88US=> NVnwSYdLW0GQR1XS
NH-12 M3XG[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWLkfnRbUUN3ME2xNE4zPDN|IN88US=> NGjaW5BUSU6JRWK=
CA46 M36wXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE\BfmRKSzVyPUGwMlM3OSEQvF2= M{HBdXNCVkeHUh?=
NCI-SNU-1 NUezZVZ1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxRTFyLkS5Olkh|ryP NVjUPYZoW0GQR1XS
SCLC-21H M2Lr[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYDkeIVjUUN3ME2xNE43PTl4IN88US=> MV\TRW5ITVJ?
EC-GI-10 NUDCfVR2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVTJR|UxRTFyLkewN|Eh|ryP NGnYSJFUSU6JRWK=
SR M2jiS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MXvJR|UxRTFzLkCxPFUh|ryP NWLLc3VWW0GQR1XS
NCI-H1648 NIXaPHNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn35TWM2OD1zMT6wPVY2KM7:TR?= MlHyV2FPT0WU
TGBC1TKB Mmn3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYLCT4xiUUN3ME2xNU41OTB{IN88US=> NH\EdFJUSU6JRWK=
EW-11 M{HmZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3rwRWlEPTB;MUGuOVE5PiEQvF2= NULJeVl7W0GQR1XS
SK-MM-2 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFLHXo5KSzVyPUGxMlgxPjFizszN M1;WTHNCVkeHUh?=
NCI-H524 MnnRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXLJR|UxRTFzLkm4NlIh|ryP Mmn0V2FPT0WU
NOS-1 NGXUUWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfDVYFKSzVyPUGyMlA{PDVizszN M2L1bHNCVkeHUh?=
AM-38 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MVnJR|UxRTF{LkW2N|Mh|ryP MU\TRW5ITVJ?
A498 NES3bJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHLlOmdKSzVyPUGyMlcxPjlizszN MXHTRW5ITVJ?
KARPAS-422 NYHwW4drT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWjGfJVnUUN3ME2xNk44PDl4IN88US=> M1TjWnNCVkeHUh?=
LU-139 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLES5l{UUN3ME2xNk46ODJ4IN88US=> MnzYV2FPT0WU
COR-L88 MljzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MofXTWM2OD1zMj65N|gzKM7:TR?= MUHTRW5ITVJ?
K5 NWLCSXJOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWPJR|UxRTF{Lkm0OlIh|ryP MXfTRW5ITVJ?
NB13 M1zLb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGmyTY1KSzVyPUGyMlk4QDNizszN NV;PdIdQW0GQR1XS
MRK-nu-1 MnTWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYDJR|UxRTF|LkG5OUDPxE1? MmHlV2FPT0WU
MHH-NB-11 NWHRW4prT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYXJR|UxRTF|LkK5NFIh|ryP MYXTRW5ITVJ?
KU812 NXHLR4ZwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2PiVWlEPTB;MUOuOlEzPCEQvF2= MWTTRW5ITVJ?
TE-12 NEmz[ZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIr6XFhKSzVyPUGzMlY6QTRizszN M{nnPHNCVkeHUh?=
NCI-N87 NX3hZVQ3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mkf3TWM2OD1zMz63N|Yh|ryP NUXENVZkW0GQR1XS
EB2 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGP0NFhKSzVyPUGzMlg2ODVizszN MYnTRW5ITVJ?
DB NGjZdnJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHTYXINKSzVyPUGzMlk5QDVizszN NV;QbmN1W0GQR1XS
697 NXPTWXB7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUTJR|UxRTF2LkS1NVEh|ryP NUf3V2trW0GQR1XS
MSTO-211H M2jJPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M130SWlEPTB;MUSuO|Q1QCEQvF2= M2rxS3NCVkeHUh?=
JVM-2 MmrCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUj3c3ZrUUN3ME2xOE44PzN3IN88US=> MoTDV2FPT0WU
COLO-824 NWi0RlFKT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1q1bGlEPTB;MUSuO|k6PCEQvF2= MoT0V2FPT0WU
BC-3 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGCzTpJKSzVyPUG1MlM6QCEQvF2= M1nFPXNCVkeHUh?=
BOKU MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV;JR|UxRTF3Lkm2NFgh|ryP NFLGdVVUSU6JRWK=
GOTO M4nCZWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MUnJR|UxRTF4Lkm2NVch|ryP NWO0ZnJKW0GQR1XS
HCC2157 NHryUHFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXXJR|UxRTF5LkS3OVUh|ryP NXHqTGZPW0GQR1XS
LS-1034 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NH;WPG1KSzVyPUG3MlY5OThizszN MV3TRW5ITVJ?
CAL-148 M{P5dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLFNFFKSzVyPUG3Mlk4QTZizszN NF:yfIZUSU6JRWK=
MOLT-4 NX3PdWR3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUnmOmtnUUN3ME2xPE45OjB6IN88US=> NXzycmRtW0GQR1XS
Daudi M1\KU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmToTWM2OD1zOD65NlMyKM7:TR?= NW\YU4xJW0GQR1XS
J-RT3-T3-5 NETiOZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlnyTWM2OD1zOT60NFY3KM7:TR?= NEWydXNUSU6JRWK=
KMOE-2 M3\XOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MWfJR|UxRTF7Lk[0PFIh|ryP MknGV2FPT0WU
HL-60 M37rRmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlXHTWM2OD1{MD6xPVY2KM7:TR?= NWn3[GpHW0GQR1XS
P31-FUJ Mn3lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXroVVVjUUN3ME2yNE41PzV|IN88US=> MWHTRW5ITVJ?
IM-9 MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MUnJR|UxRTJyLk[yNlQh|ryP MV7TRW5ITVJ?
HDLM-2 NGrJXFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2DUNGlEPTB;MkCuPFgzOSEQvF2= NYCxcZFQW0GQR1XS
NCI-H1304 M{XIXGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4ewSWlEPTB;MkGuNFMyOSEQvF2= MlzDV2FPT0WU
NCI-H345 NE\KbmpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3LvfmlEPTB;MkGuNFY1OyEQvF2= NHfHRVVUSU6JRWK=
RPMI-6666 MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4TKeGlEPTB;MkGuN|YxOiEQvF2= MXnTRW5ITVJ?
GR-ST MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYDJR|UxRTJzLkSxO{DPxE1? MXzTRW5ITVJ?
CHP-126 MoW4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Ml:5TWM2OD1{MT62NVgyKM7:TR?= M1XoPXNCVkeHUh?=
EHEB NVHFR|Y5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYDqfG5NUUN3ME2yNU43PzNzIN88US=> MXTTRW5ITVJ?
CPC-N NGPkXnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnHTWM2OD1{ND6wNlAyKM7:TR?= MXXTRW5ITVJ?
NB1 M4[yXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoO0TWM2OD1{ND62PVM6KM7:TR?= MXLTRW5ITVJ?
LS-123 NYnEWIhmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYiy[GlmUUN3ME2yOE46ODF{IN88US=> MlzJV2FPT0WU
ST486 NY\QWlQ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoDsTWM2OD1{NT6xNVE{KM7:TR?= Mnz0V2FPT0WU
NCI-H1963 MknNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1\IXmlEPTB;Mk[uNFYzOyEQvF2= MY\TRW5ITVJ?
U-87-MG NUjMXWg5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWmxUIRSUUN3ME2yOk44PjR2IN88US=> M1L5V3NCVkeHUh?=
COR-L279 Mmn1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkXUTWM2OD1{Nj63PVIzKM7:TR?= MoHvV2FPT0WU
LU-165 MlnrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV7XOnY4UUN3ME2yPE4xQDZzIN88US=> NGHycG5USU6JRWK=
COLO-800 M3u4fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlPqTWM2OD1{OD6yPVU3KM7:TR?= MYLTRW5ITVJ?
ETK-1 MmDQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkW1TWM2OD1{OD6zOFQ3KM7:TR?= NUGwb2NSW0GQR1XS
LNCaP-Clone-FGC Ml\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYrJR|UxRTJ7LkmyPFEh|ryP Mo\RV2FPT0WU
SIG-M5 NEXaUJVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml;WTWM2OD1|MD63PVUzKM7:TR?= MWTTRW5ITVJ?
NB6 NXXsRo1oT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{\PS2lEPTB;M{CuPVUxOyEQvF2= NYnVcFc3W0GQR1XS
NCI-H2107 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoPLTWM2OD1|MT6yN|M5KM7:TR?= MmjzV2FPT0WU
SNU-C1 MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYrJR|UxRTNzLkOxNlYh|ryP NHXQRWhUSU6JRWK=
JAR NGfWZ21Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1Tvb2lEPTB;M{GuN|c6QSEQvF2= M4TodXNCVkeHUh?=
L-363 MWfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX;JR|UxRTN{LkKxOFQh|ryP M2TzR3NCVkeHUh?=
EW-24 NXHpcJBtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3rMV2lEPTB;M{KuN|Q4PCEQvF2= NILsS|RUSU6JRWK=
NB69 MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmHqTWM2OD1|Mz62OFU1KM7:TR?= M2Pxd3NCVkeHUh?=
EW-13 NIXXfVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHXIR5RKSzVyPUOzMlg6PjlizszN MnX6V2FPT0WU
Ramos-2G6-4C10 M1S1eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEH3VnpKSzVyPUO0MlI6QTNizszN NUnZfFh5W0GQR1XS
TE-11 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmjXTWM2OD1|ND60PFIzKM7:TR?= M1z4O3NCVkeHUh?=
L-428 MmizS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUXJR|UxRTN2Lke1N|Yh|ryP NVH4PZBMW0GQR1XS
KP-N-YN MUjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{i2dWlEPTB;M{SuPVA2PyEQvF2= NVThXo86W0GQR1XS
CGTH-W-1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV;hRo9FUUN3ME2zOk46ODR6IN88US=> MY\TRW5ITVJ?
K-562 MonWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M33jemlEPTB;M{euNFg3PCEQvF2= MUjTRW5ITVJ?
NCI-H1299 NH7UfWVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFXrPI1KSzVyPUO4MlE3ODNizszN M4T2[nNCVkeHUh?=
RCC10RGB NH7iO4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUHDV5g3UUN3ME2zPE4zODh|IN88US=> M4fFN3NCVkeHUh?=
NCI-SNU-16 NXrxNW5CT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkPPTWM2OD1|OD61OlU{KM7:TR?= MnjTV2FPT0WU
LC-2-ad NILXfoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHHvXFJKSzVyPUO5MlQ{OzdizszN NFPKeItUSU6JRWK=
MHH-PREB-1 M2\RTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEjBV3ZKSzVyPUO5Mlc{QDhizszN NGLCR2pUSU6JRWK=
NCI-H64 NYDJcYQ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1q4TWlEPTB;NECuNFk1QCEQvF2= NVL0c|dUW0GQR1XS
LB996-RCC MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnTMTWM2OD12MD64O|E3KM7:TR?= MWnTRW5ITVJ?
DEL MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWXJR|UxRTRzLkS0NFUh|ryP M1zpNXNCVkeHUh?=
MLMA MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEf5eW1KSzVyPUSxMlc2QTVizszN M37YOnNCVkeHUh?=
SBC-1 Ml\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2X0OWlEPTB;NEKuNVgxPiEQvF2= NEDqOYxUSU6JRWK=
MPP-89 NWDqe45xT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NIDWVJBKSzVyPUSyMlU5PzVizszN NUfUeohJW0GQR1XS
MV-4-11 NXm0b2E6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1nVfWlEPTB;NEKuPVA3PyEQvF2= M{DHOHNCVkeHUh?=
EoL-1- NWnLZ2d5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGj4e4lKSzVyPUS0MlE2PjhizszN MXfTRW5ITVJ?
CW-2 M{Py[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXvUVG1EUUN3ME20OE45OzR{IN88US=> MoDMV2FPT0WU
HT NWrWXWZ2T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWHJR|UxRTR3LkewNFch|ryP MmHGV2FPT0WU
SW954 MkL0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUDuempSUUN3ME20O{41OTJ6IN88US=> M1HUXnNCVkeHUh?=
A3-KAW NV7kU5pLT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MorRTWM2OD12OT64NFYyKM7:TR?= NX62b3JrW0GQR1XS
TC-YIK NYrLbokxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWP1NIZ6UUN3ME21NE4xOzZ|IN88US=> MX;TRW5ITVJ?
SW962 NWLXc4M6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MV\JR|UxRTV2LkizOVch|ryP M{jBOHNCVkeHUh?=
KP-N-RT-BM-1 M3vWR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVHW[4t3UUN3ME21Ok43PjN6IN88US=> MYjTRW5ITVJ?
NCI-H1395 NIfUZ4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M2W5SGlEPTB;NUiuPFE4OiEQvF2= NGKweYRUSU6JRWK=
RPMI-8402 M1;MXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHzP[VFKSzVyPUW4Mlk2OjZizszN MnvKV2FPT0WU
SCH MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIHTcnhKSzVyPU[wMlk3OzhizszN MYHTRW5ITVJ?
NCI-H2196 NWHaZWI5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWDJR|UxRTZzLkKzNUDPxE1? NXXhN3VVW0GQR1XS
LOXIMVI Mo\YS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWHINHFyUUN3ME22NU45OjZ4IN88US=> M3PlNHNCVkeHUh?=
TGBC24TKB MX3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXLmS2h3UUN3ME22Nk4yPDlzIN88US=> MU\TRW5ITVJ?
SK-MEL-2 NGLWNWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYjITFU3UUN3ME22N{46QDl{IN88US=> M{HjT3NCVkeHUh?=
U-698-M MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEnnVHhKSzVyPU[4MlU3QDdizszN MmPCV2FPT0WU
NCI-H1522 M37YNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFLlfm9KSzVyPU[5MlAxPDdizszN M3vTO3NCVkeHUh?=
UACC-812 NXv3flhST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV[zdnk1UUN3ME22PU42OjB7IN88US=> MW\TRW5ITVJ?
MHH-CALL-2 MoPIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXHJR|UxRTdyLkC2JO69VQ>? NHHHUYdUSU6JRWK=
NB5 NF7mWWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1\1fWlEPTB;N{CuN|Q3QCEQvF2= MUfTRW5ITVJ?
KARPAS-299 NHzUNZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NV\1TnVRUUN3ME23NE41PDR5IN88US=> NG\PS|VUSU6JRWK=
NCI-H1694 NFf5c2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYjJR|UxRTdzLkCzNkDPxE1? NYPq[mVuW0GQR1XS
NCI-H82 NWfKU211T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxRTdzLkm1NFch|ryP M{G2eHNCVkeHUh?=
SCC-15 MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXrJR|UxRTd{LkO0JO69VQ>? NWrNTGx2W0GQR1XS
NCI-H1436 NX;PR5FRT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWLJNVJJUUN3ME23Nk44PDV4IN88US=> NU[3SY9kW0GQR1XS
ATN-1 MmS4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NYnvTlJMUUN3ME23OE42ODVizszN MWTTRW5ITVJ?
RPMI-8866 NYr1WmdxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jpXWlEPTB;N{SuO|UxQSEQvF2= MlvWV2FPT0WU
HCC1599 NWnVfVkxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWfJR|UxRTd2Lki3N|Ih|ryP NVH3cVNIW0GQR1XS
NCI-H1155 NU\jbVVyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkHVTWM2OD15ND65N|Y4KM7:TR?= MX\TRW5ITVJ?
DOHH-2 M{TxTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlzrTWM2OD15ND65OVE1KM7:TR?= M3yxNXNCVkeHUh?=
SK-NEP-1 M2nUcWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmjNTWM2OD15NT6wO|U1KM7:TR?= NXrrfllpW0GQR1XS
HCC1187 MkXUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHnw[npKSzVyPUe3MlYyOjJizszN MYHTRW5ITVJ?
NCI-H322M MWHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVPIboNyUUN3ME23PE4{PzB7IN88US=> M3;VXHNCVkeHUh?=
NCI-H526 NYPCRWpNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVjJR|UxRTd6LkW4O|ch|ryP MXvTRW5ITVJ?
NCI-H2171 MkLIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWLhdndEUUN3ME23PU41OTN4IN88US=> M3PBPXNCVkeHUh?=
COLO-668 M3XxR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3XocWlEPTB;OEGuOVg5PCEQvF2= NWH6OmYzW0GQR1XS
RS4-11 M2frV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYPQc5lvUUN3ME24Nk4zPTB3IN88US=> M2SxT3NCVkeHUh?=
NCI-H716 NYnWbFZmT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEfZcWxKSzVyPUiyMlkxPzVizszN MV;TRW5ITVJ?
LU-134-A NF;3foxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVXJR|UxRTh|LkGzOVEh|ryP NGm3U3VUSU6JRWK=
RPMI-8226 MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1rtb2lEPTB;OESuNlExPyEQvF2= NH[2S2tUSU6JRWK=
KY821 MnnWS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoGxTWM2OD17MT62OVUyKM7:TR?= NXSyN5A5W0GQR1XS
ECC4 M3r3VGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUX4Z4ExUUN3ME25N{45OjZ7IN88US=> M1PUd3NCVkeHUh?=
EW-3 NU[5N|F3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGfBcpNKSzVyPUm0MlkxQDFizszN MoLzV2FPT0WU
NB7 NFuzW45Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVLJR|UxRTl3Lke3PFYh|ryP MYDTRW5ITVJ?
NCI-H720 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmPLTWM2OD17OD60NFYyKM7:TR?= NEjYeoZUSU6JRWK=
NCI-H446 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn\UTWM2OD17OT63OVg5KM7:TR?= M3v2NXNCVkeHUh?=
NCI-H889 MkDCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1n4cGlEPTB;MUC0MlI1OiEQvF2= MYfTRW5ITVJ?
EW-22 NYnzOHFqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYrUZZVUUUN3ME2xNFYvOTlizszN M4XnVHNCVkeHUh?=
BV-173 MnTqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MX7JR|UxRTFyOD63Nlgh|ryP MoXJV2FPT0WU
WSU-NHL MonGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1j4d2lEPTB;MUC5MlY4OSEQvF2= MW\TRW5ITVJ?
MN-60 M4O3dWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NInBUoRKSzVyPUGwPU43QSEQvF2= MX3TRW5ITVJ?
DG-75 Mm\mS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFzkSJdKSzVyPUGxN{4{PTJizszN M{\4enNCVkeHUh?=
DMS-79 NITkRppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmPGTWM2OD1zMUeuN|gzKM7:TR?= MUDTRW5ITVJ?
SK-MEL-1 M1rTVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoLzTWM2OD1zMUiuNFA6KM7:TR?= NXrONWpZW0GQR1XS
DMS-153 NGLXXG9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXTJR|UxRTF{MT63OFUh|ryP Ml7yV2FPT0WU
NCI-H510A MkS2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4jKOmlEPTB;MUK3MlMzKM7:TR?= M3HhOXNCVkeHUh?=
BE-13 NUOyW3VNT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NHjBXVNKSzVyPUGzOE4xPDRizszN MVzTRW5ITVJ?
KP-N-YS NYH0ToNzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M13IfWlEPTB;MUO5Mlc{PiEQvF2= M4G3[3NCVkeHUh?=
SUP-T1 MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MYXJR|UxRTF2Mz63NFgh|ryP M{i1UHNCVkeHUh?=
EW-12 MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M13DeWlEPTB;MUS0MlY6QSEQvF2= M1jYWHNCVkeHUh?=
NB14 NHO0dIhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLrV|dKSzVyPUG0O{4xQDJizszN NFnodJlUSU6JRWK=
MDA-MB-134-VI M2HwVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\TU2lEPTB;MUS4MlI3QCEQvF2= M1zhOnNCVkeHUh?=
NCI-H1770 M3Xzbmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYXINIFlUUN3ME2xOVYvOjd7IN88US=> NIniOXFUSU6JRWK=
TUR MnPFS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUfJR|UxRTF4Nz64O{DPxE1? NVOwe5RQW0GQR1XS
NCI-H1417 M1j1[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M3\6WGlEPTB;MUiwMlM{OSEQvF2= NHzVeWpUSU6JRWK=
IMR-5 NF\vPVdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;UN2VKSzVyPUG4NU42PzFizszN NGXQXmdUSU6JRWK=
NCI-H226 NUXFcm5lT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUXJR|UxRTF6OD64OlYh|ryP MX\TRW5ITVJ?
NCI-H187 NELEW2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlPyTWM2OD1zOUCuNFY1KM7:TR?= M2HKeXNCVkeHUh?=
SF539 M2O5VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXrCXVd6UUN3ME2xPVIvPzJ6IN88US=> M{X1VHNCVkeHUh?=
TALL-1 M{m4SWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4XSWWlEPTB;MUm4MlMxPCEQvF2= NIXkd3RUSU6JRWK=
TE-441-T M{HqNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MojpTWM2OD1zOUmuO|M6KM7:TR?= M2rhO3NCVkeHUh?=
REH MmXYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NF3SXGRKSzVyPUKzOk43OjZizszN MUjTRW5ITVJ?
MS-1 NYXEdWRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkO3TWM2OD1{M{muNVIyKM7:TR?= NHPPe3dUSU6JRWK=
THP-1 M2HBdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTHTWM2OD1{NkSuO|M5KM7:TR?= MYjTRW5ITVJ?
NCI-H1838 NH2z[m9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlP1TWM2OD1{N{GuOFU3KM7:TR?= MlrGV2FPT0WU
P30-OHK MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX\JR|UxRTJ6Mz64OFch|ryP NYXLXlVLW0GQR1XS
C8166 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmG0TWM2OD1|NEWuN|M5KM7:TR?= M4\TdXNCVkeHUh?=

... Click to View More Cell Line Experimental Data

In vivo Administration of MG-132 effectively rescues the expression levels and plasma membrane localization of dystrophin, β-dystroglycan, α-bdystroglycan, and α-sarcoglycan in skeletal muscle fibers from mdx mice, reduces muscle membrane damage, and ameliorates the histopathological signs of muscular dystrophy. [7] MG-132 treatment significantly reduces immobilization-induced skeletal muscle atrophy in mice, by downregulating the muscle-specific ubiquitin ligases atrogin-1/MAFbx and MuRF-1 mRNA. [8]

Protocol

Kinase Assay:

[1]

+ Expand

Measurement of inhibitory activities of MG-132 against 20S proteasome:

The reaction mixture for the 20S proteasome inhibitory assay contains 0.1 M Tris-acetate, pH 7.0, 20S proteasome, MG-132, and 25 μM substrate dissolved in dimethyl sulfoxide in a final volume of 1 mL. After incuba tion at 37 °C for 15 minutes, the reaction is stopped by the addition of 0.1 mL of 10% SDS and 0.9 mL of 0.1M Tris acetate, pH 9.0. The fluorescence of the reaction products is measured. To determine the IC50 against 20S proteasome, various concentrations of MG-132 are included in the assay mixture.
Cell Research:

[3]

+ Expand
  • Cell lines: KIM-2, HC11, and ES
  • Concentrations: Dissolved in DMSO, final concentrations ~25 μM
  • Incubation Time: 24 and 48 hours
  • Method:

    Cells are exposed to various concentrations of MG-132 for 24, and 48 hours. Supernatant and monolayer cells are harvested by centrifugation and fixed in 70% ethanol in PBS for staining with acridine orange. Equal volumes of cells and acridine orange (5 mg/mL in PBS) are mixed on a microscope slide and examined by fluorescence microscopy. For annexin V analysis, cells are harvested by centrifugation and stained with annexin V and propidium iodide. For cell cycle analysis, cells are rehydrated in PBS at room temperature for 10 minutes, followed by staining with propidium iodide (5 mg/mL). All samples are analyzed using a Coulter Epics XL flow cytometer.


    (Only for Reference)
Animal Research:

[7]

+ Expand
  • Animal Models: Male mdx (C57BL/10ScSn DMD mdx) mice
  • Formulation: Dissolved in DMSO, and diluted in PBS
  • Dosages: ~10 μg/kg/day
  • Administration: Injection
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 90 mg/mL (189.22 mM)
Ethanol 25 mg/mL (52.56 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
4% DMSO+30% PEG 300+20% propylene glycol+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 475.62
Formula

C26H41N3O5

CAS No. 133407-82-6
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    I want to know whether it contains EDTA or other chelating agent in this product(S2619)?

  • Answer:

    Our S2619 MG-132 doesn't contain EDTA or other chelating agent.

Proteasome Signaling Pathway Map

Proteasome Inhibitors with Unique Features

Related Proteasome Products4

Tags: buy MG-132 | MG-132 supplier | purchase MG-132 | MG-132 cost | MG-132 manufacturer | order MG-132 | MG-132 distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID