CAS No. 137-66-6
| CAS Number | 137-66-6 | |
|---|---|---|
| Molecular Formula |
C22H38O7 |
|
| Molecular Weight (MW) | 414.53 | |
| SMILES | CCCCCCCCCCCCCCCC(=O)OCC(C1C(=C(C(=O)O1)O)O)O |
L-Ascorbyl 6-palmitate is a synthetic lipophilic derivative of L-ascorbic acid that acts as an antioxidant and dietary inhibitor of tumor promotion. Treatment with L-ascorbyl 6-palmitate significantly inhibits 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor promotion in murine models. Mechanistically, L-ascorbyl 6-palmitate suppresses epidermal lipid peroxidation and ornithine decarboxylase activity, thereby mitigating oxidative stress, attenuating downstream inflammatory pathways, and reducing epidermal hyperproliferation. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(200.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 83 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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