Ferulic Acid

Catalog No.S2300 Synonyms: Fumalic Acid

For research use only.

Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.

Ferulic Acid Chemical Structure

CAS No. 1135-24-6

Selleck's Ferulic Acid has been cited by 3 Publications

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Biological Activity

Description Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong. Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3.78 μM and 12.5 μM for FGFR1 and FGFR2, respectively.
Targets
FGFR1 [1]
(Cell-free assay)
FGFR2 [1]
(Cell-free assay)
3.78 μM 12.5 μM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 194.19
Formula

C10H10O4

CAS No. 1135-24-6
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=C(C=CC(=C1)C=CC(=O)O)O

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02731755 Completed Other: Oat|Other: Control Healthy University of Reading|Biotechnology and Biological Sciences Research Council|Rothamsted Research|PepsiCo Global R&D|University of Roehampton January 2016 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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